M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
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Journal ArticleDOI
Neoadjuvant Radiochemotherapy Significantly Alters the Phenotype of Plasmacytoid Dendritic Cells and 6-Sulfo LacNAc+ Monocytes in Rectal Cancer.
Felix Wagner,Ulrike Hölig,Friederike Wilczkowski,Ioana Plesca,Ulrich Sommer,Rebekka Wehner,Rebekka Wehner,Maximilian Kießler,Armin Jarosch,Katharina Flecke,Maia Arsova,Antje Tunger,Andreas Bogner,Christoph Reißfelder,Jürgen Weitz,Jürgen Weitz,Knut Schäkel,Esther G.C. Troost,Mechthild Krause,Gunnar Folprecht,Gunnar Folprecht,Martin Bornhäuser,Martin Bornhäuser,Michael Bachmann,Daniela E. Aust,Gustavo Baretton,Marc Schmitz,Marc Schmitz +27 more
TL;DR: It is observed that nRCT markedly enhances the percentage of inducible nitric oxide synthase (iNOS)- or tumor necrosis factor (TNF) alpha-producing slanMo in rectal cancer tissues and pDCs locally expressing interferon-alpha was significantly higher in post-nRCT tissues compared to pre-n RCT tumor specimens.
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Expression of the HIV-1 Nef protein in the baculovirus system: investigation of anti-Nef antibodies response in human sera and subcellular localization of Nef.
Norbert Kienzle,M. Enders,Marion Buck,H. Siakkou,S. Jahn,G. Petzold,K. E. Schneweis,Michael Bachmann,W. E. G. Müller,Nikolaus Müller-Lantzsch +9 more
TL;DR: Recombinant Nef protein frequently reacted with seropositive sera of HIV-1 and HIV-2 infected patients and Confocal laser scanning microscopy demonstrated that Nef is present both in the cytoplasm and in the nucleus, indicating thatNef might directly function on gene expression.
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Rigorous assessment of patterning solution of metal layer in 7 nm technology node
Weimin Gao,Weimin Gao,Ivan Ciofi,Yves Saad,Philippe Matagne,Michael Bachmann,Werner Gillijns,Kevin Lucas,Wolfgang Demmerle,Thomas Schmoeller +9 more
TL;DR: In this article, a simulation tool that enables emulation of the whole patterning flow with realistic process-dependent three-dimensional (3-D) profile and topology was used to investigate the impact of process variations on dielectric reliability.
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Structure-Based Design, Optimization, and Development of [18F]LU13: A Novel Radioligand for Cannabinoid Receptor Type 2 Imaging in the Brain with PET.
Daniel Gündel,Winnie Deuther-Conrad,Lea Ueberham,Sarandeep Kaur,Elina Otikova,Rodrigo Teodoro,Magali Toussaint,Thu Hang Lai,Oliver Clauß,Matthias Scheunemann,Guy Bormans,Michael Bachmann,Klaus Kopka,Peter Brust,Rareş Moldovan +14 more
TL;DR: PET imaging with [18F]LU13 in a rat model of vector-based/-related hCB2R overexpression in the striatum revealed a high signal-to-background ratio and the new radioligand showed high CB2R affinity in vitro as well as high metabolic stability in vivo.
Journal ArticleDOI
Tregs activated by bispecific antibodies: Killers or suppressors?
Stefanie Koristka,Marc Cartellieri,Claudia Arndt,Anja Feldmann,Barbara Seliger,Gerhard Ehninger,Michael Bachmann +6 more
TL;DR: Bispecific antibodies for target-specific redirection of T cells in order to eliminate malignant cells and CD3-engaging constructs might also activate T regulatory cells present in the tumor microenvironment.