Michael Bachmann

TL;DR: It is demonstrated that UniCAR T-cells, armed with anti-CD10 TM, can efficiently kill B-ALL cell lines, as well as patient-derived B-all blasts, thereby highlighting the exciting possibility for using CD10 as an emerging therapeutic target for B-cell malignancies.

TL;DR: In this paper, a roll-back stopping process for a motor vehicle is described, where the vehicle driving direction corresponding to the engaged gear stage is determined, the direction of displacement of the vehicle is determined and, should the vehicle displacement be opposite to the driving direction, a driver-independent braking operation is executed on the wheels of at least one axle.

TL;DR: In this paper , a first- or second-generation universal CAR (UniCAR) and target modules (TMs) were generated to target cells with so-called target modules which harbor an ErbB2 (HER2)-specific antibody domain for target cell binding and the E5B9 peptide recognized by the UniCAR.

TL;DR: In this article , the microcanonical inflection point analysis method was employed for the identification and classification of phase transitions in systems of any size, to study the two-dimensional Ising model at various lattice sizes and in the thermodynamic limit.

TL;DR: In this article , a method to generate a large amount of agarose microbeads that mimic the natural culture conditions experienced by bacteria to co-encapsulate two strains of fluorescence-labeled Escherichia coli was introduced.