M
Michael Bachmann
Researcher at Helmholtz-Zentrum Dresden-Rossendorf
Publications - 402
Citations - 16252
Michael Bachmann is an academic researcher from Helmholtz-Zentrum Dresden-Rossendorf. The author has contributed to research in topics: Antigen & Chimeric antigen receptor. The author has an hindex of 63, co-authored 360 publications receiving 14388 citations. Previous affiliations of Michael Bachmann include ACADIA Pharmaceuticals Inc. & University of Southern California.
Papers
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Journal ArticleDOI
HIF2alpha-Associated Pseudohypoxia Promotes Radioresistance in Pheochromocytoma: Insights from 3D Models
Verena Seifert,Verena Seifert,Susan Richter,Nicole Bechmann,Michael Bachmann,Christian G. Ziegler,Jens Pietzsch,Jens Pietzsch,Martin Ullrich +8 more
TL;DR: In this paper, the effects of hypoxia-inducible factor 2 alpha (HIF2α) on the susceptibility of PCCs/PGLs to radiation treatments using spheroids grown from genetically engineered mouse pheochromocytoma (MPC) cells.
Journal ArticleDOI
Enhancing The Efficacy and Specificity Of Antibody-Based T Cell Retargeting Strategies Against Hematological Malignancies
Claudia Arndt,Marc Cartellieri,Roberta Aliperta,Stefanie Koristka,Irene Michalk,Martin Bornhäuser,Gerhard Ehninger,Michael Bachmann,Anja Feldmann +8 more
TL;DR: In vitro and in vivo data clearly underline that the combination of the established effector module with different target modules efficiently activated T cells against hematological malignancies.
Journal ArticleDOI
Analysis of expression of the gene encoding for the nuclear autoantigen La/SS-B using reportergene constructs
TL;DR: Exon 1 and exon 1' transcripts were correctly transcribed and spliced from the La luciferase fusion construct and the 5'-start of the respective transcript allowed to identify those genomic regions in the La gene that were most likely being involved in determining the respective transcription initiation site.
Book ChapterDOI
Use of Nonradioactive Detection Method for North- and South-Western Blot.
TL;DR: The use of a northwestern and southwestern blot protocol is described for the evaluation of the DNA and RNA binding abilities of a novel putative methyl transferase HSPC133 (METTL5).
Journal ArticleDOI
Correlation of anti-cytoskeleton antibody activities in synovial fluid with interleukin-6 in patients with osteoarthritis and inflammatory joint disease.
Werner-Johannes Mayet,Elisabeth Hermann,Michael Bachmann,Michael Manns,K H Meyer zum Büschenfelde +4 more
TL;DR: It is shown for the first time that IL-6 seems to induce synovial fluid antibody activities restricted to cytoskeletal components of synoviocytes (i.e., vimentin and actin) that appear to be markers of activity in patients with inflammatory joint disease.