M
Michel Farnier
Researcher at Regeneron
Publications - 105
Citations - 7627
Michel Farnier is an academic researcher from Regeneron. The author has contributed to research in topics: Alirocumab & PCSK9. The author has an hindex of 28, co-authored 105 publications receiving 4785 citations. Previous affiliations of Michel Farnier include Merck & Co. & French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Safety and Efficacy of Long-Term Co-Administration of Fenofibrate and Ezetimibe in Patients With Mixed Hyperlipidemia
James M. McKenney,Michel Farnier,Kwok-Wing Lo,Harold E. Bays,Inna Perevozkaya,Gary Carlson,Michael J. Davies,Yale B. Mitchel,Barry Gumbiner +8 more
TL;DR: Long-term, 48-week co-administration of F ENO plus EZE was well tolerated and more efficacious than FENO in patients with mixed hyperlipidemia.
Journal ArticleDOI
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Antonio J. Vallejo-Vaz,C. Stevens,Alexander R.M. Lyons,Kanika I. Dharmayat,Tomáš Freiberger,G. Kees Hovingh,Pedro Mata,Frederick J. Raal,Raul D. Santos,Handrean Soran,Gerald F. Watts,Marianne Abifadel,Carlos A. Aguilar-Salinas,Khalid F. AlHabib,Mutaz Alkhnifsawi,Wael Almahmeed,Fahad Alnouri,Rodrigo Alonso,Khalid Al-Rasadi,Ahmad Al-Sarraf,Nasreen Al-Sayed,Francisco Araujo,T.F. Ashavaid,Maciej Banach,Sophie Béliard,Marianne Benn,Christoph J. Binder,Martin P. Bogsrud,Mafalda Bourbon,Krzysztof Chlebus,Pablo Corral,Kairat Davletov,Olivier S. Descamps,Ronen Durst,Marat V. Ezhov,Dan Gaita,Jacques Genest,Urh Groselj,Mariko Harada-Shiba,Kirsten B. Holven,Meral Kayıkçıoğlu,Weerapan Khovidhunkit,Katarina Lalic,Gustavs Latkovskis,Ulrich Laufs,Evangelos Liberopoulos,Marcos M. Lima-Martínez,Jie Lin,Vincent Maher,A. David Marais,Winfried März,Erkin M. Mirrakhimov,André R. Miserez,Olena Mitchenko,Hapizah Nawawi,Børge G. Nordestgaard,Andrie G. Panayiotou,György Paragh,Zaneta Petrulioniene,Belma Pojskic,Arman Postadzhiyan,Katarina Raslova,Ashraf Reda,Željko Reiner,Fouzia Sadiq,Wilson E Sadoh,Heribert Schunkert,Aleksandr B. Shek,Mario Stoll,Erik S.G. Stroes,Ta-Chen Su,Tavintharan Subramaniam,Andrey V. Susekov,Myra Tilney,Brian Tomlinson,Thanh Huong Truong,Alexandros D. Tselepis,Anne Tybjærg-Hansen,Alejandra Vázquez Cárdenas,Margus Viigimaa,Luya Wang,Shizuya Yamashita,John J.P. Kastelein,Eric Bruckert,Branislav Vohnout,Laura Schreier,Jing Pang,C. Ebenbichler,Hans Dieplinger,Reinhold Innerhofer,Yvonne Winhofer-Stöckl,Susanne Greber-Platzer,Konstantin Krychtiuk,Walter Speidl,Hermann Toplak,Kurt Widhalm,Thomas M. Stulnig,Kurt Huber,Florian Höllerl,Gersina Rega-Kaun,Lucas Kleemann,Martin Mäser,Sabine Scholl-Bürgi,Christoph Säly,Florian J. Mayer,Gaelle Sablon,Eric Tarantino,Charlotte Nzeyimana,Lamija Pojskic,Ibrahim Sisic,Azra D. Nalbantic,Cinthia E. Jannes,Alexandre C. Pereira,José Eduardo Krieger,Ivo Petrov,Assen Goudev,Fedya Nikolov,Snejana Tisheva,Yoto Yotov,Ivajlo Tzvetkov,Alexis Baass,Jean Bergeron,Sophie Bernard,Diane Brisson,Liam R. Brunham,Lubomira Cermakova,Patrick Couture,Gordon A. Francis,Daniel Gaudet,Robert A. Hegele,Etienne Khoury,G.B. John Mancini,Brian W. McCrindle,Martine Paquette,Isabelle Ruel,Ada Cuevas,Sylvia Asenjo,Xumin Wang,Kang Meng,Xiantao Song,Qiang Yong,Tao Jiang,Ziyou Liu,Yanyu Duan,Jing Hong,Pucong Ye,Yan Chen,Jianguang Qi,Zesen Liu,Yuntao Li,Chaoyi Zhang,Jie Peng,Ya Yang,Wei Yu,Qian Wang,Hui Yuan,Shitong Cheng,Long Jiang,Mei Chong,Jian Jiao,Yue Wu,Wenhui Wen,Liyuan Xu,Ruiying Zhang,Yichen Qu,Jianxun He,Xuesong Fan,Zhenjia Wang,Elaine Chow,Ivan Pećin,Dražen Perica,Phivos Symeonides,Michal Vrablík,Richard Ceska,Vladimir Soska,Lukas Tichy,Vera Adamkova,Jana Franekova,Renata Cifkova,Pavel Kraml,Katerina Vonaskova,Jana Cepova,Magdalena Dusejovska,Lenka Pavlickova,Vladimir Blaha,Hana Rosolova,Barbora Nussbaumerova,Roman Cibulka,Helena Vaverkova,Lubica Cibickova,Zdenka Krejsova,Katerina Rehouskova,Pavel Malina,Milena Budikova,Vaclava Palanova,Lucie Solcova,Alena Lubasova,Helena Podzimkova,Juraj Bujdak,Jiri Vesely,Marta Jordanova,Tomas Salek,Robin Urbanek,Stanislav Zemek,Jan Lacko,Hana Halamkova,Sona Machacova,Sarka Mala,Eva Cubova,Katerina Valoskova,Lukas Burda,Ahmed Bendary,Ihab Daoud,Sameh Emil,Atef Elbahry,Samir Rafla,Osama Sanad,Ghada Kazamel,Mohamed Ashraf,Mohamed Sobhy,Amro El-Hadidy,Mohamed A. Shafy,Saif Kamal,Mohamed Bendary,Grete Talviste,Denis Angoulvant,Franck Boccara,Bertrand Cariou,Valérie Carreau,Alain Carrié,Sybil Charrieres,Yves Cottin,Mathilde Di-Fillipo,Pierre Henri Ducluzeau,Sonia Dulong,V. Durlach,Michel Farnier,Emile Ferrari,Dorota Ferrieres,Jean Ferrières,Antonio Gallo,Régis Hankard,Jocelyne Inamo,Julie Lemale,Philippe Moulin,F. Paillard,Noël Peretti,Agnes Perrin,Alain Pradignac,Jean Pierre Rabes,Vincent Rigalleau,Ariane Sultan,Francois Schiele,Patrick Tounian,René Valéro,Bruno Vergès,Cécile Yelnik,Olivier Ziegler,Ira A. Haack,Nina Schmidt,Alexander Dressel,Isabel Klein,Jutta Christmann,Antonia Sonntag,Christine Stumpp,Diana Boger,Dana Biedermann,Monica M.N. Usme,F. Ulrich Beil,Gerald Klose,Christel König,Ioanna Gouni-Berthold,Britta Otte,Gereon Böll,Anja Kirschbaum,Jürgen Merke,Johannes Scholl,Thomas Segiet,Marco Gebauer,Florentina Predica,Manfred Mayer,Frank Leistikow,Sabine Füllgraf-Horst,Cornelius Müller,Melanie Schüler,Judith Wiener,Konrad Hein,Peter Baumgartner,Stefan Kopf,Reinhold Busch,Michael Schömig,Stephan Matthias,Nicole Allendorf-Ostwald,Bruno Fink,Dieter Böhm,Alexander Jäkel,Ann-Cathrin Koschker,Rüdiger Schweizer,Anja Vogt,Klaus G. Parhofer,Wolfgang König,Wibke Reinhard,Andrea Bäßler,Alexander Stadelmann,Volker Schrader,Julius Katzmann,Adrienne Tarr,Elisabeth Steinhagen-Thiessen,Ursula Kassner,Gerret Paulsen,Jürgen Homberger,Claudia Zemmrich,Wolfgang Seeger,Kathrin Biolik,Dorothee Deiss,Corinna Richter,Elina Pantchechnikova,Elena Dorn,Ulrike Schatz,Ulrich Julius,Antje Spens,Tobias Wiesner,Michael Scholl,Christos V. Rizos,Nikolaos Sakkas,Moses Elisaf,Ioannis Skoumas,Konstantinos Tziomalos,Loukianos S. Rallidis,Vasileios Kotsis,Michalis Doumas,Vasileios Athyros,Emmanouil Skalidis,Genovefa Kolovou,Anastasia Garoufi,E. Bilianou,Iosif Koutagiar,D. Agapakis,E. Kiouri,Christina Antza,Niki Katsiki,Evangelos A. Zacharis,Achilleas Attilakos,G. Sfikas,Charalambos Koumaras,Panagiotis Anagnostis,Georgia Anastasiou,George Liamis,Amalia-Despoina Koutsogianni,Zsolt Karányi,Mariann Harangi,László Bajnok,Mária Audikovszky,László Márk,Béla Benczúr,István Reiber,Gergely Nagy,András Nagy,Lakshmi L. Reddy,Swarup A.V. Shah,Chandrashekhar K. Ponde,Jamshed J. Dalal,Jitendra P.S. Sawhney,Ishwar C. Verma,Mays Altaey,Khalid Al-Jumaily,Dilshad Rasul,Ali F. Abdalsahib,Amer A. Jabbar,Mohanad Al-ageedi,Ruth Agar,Hofit Cohen,Avishay Ellis,Dov Gavishv,Dror Harats,Yaacov Henkin,Hila Knobler,Leah Leavit,Eran Leitersdorf,Ardon Rubinstein,Daniel Schurr,Shoshi Shpitzen,Auryan Szalat,Manuela Casula,Veronica Zampoleri,Marta Gazzotti,Elena Olmastroni,Riccardo Sarzani,Claudio Ferri,Elena Repetti,Carlo Sabbà,Antonio Bossi,Claudio Borghi,Sandro Muntoni,Francesco Cipollone,Francesco Purrello,Arturo Pujia,Angelina Passaro,Rossella Marcucci,Valerio Pecchioli,Livia Pisciotta,Giuseppe Mandraffino,Fabio Pellegatta,Giuliana Mombelli,Adriana Branchi,A.M. Fiorenza,Cristina Pederiva,Josè Pablo Werba,Gianfranco Parati,Francesca Carubbi,Lorenzo Iughetti,Arcangelo Iannuzzi,Gabriella Iannuzzo,Paolo Calabrò,Maurizio Averna,Giacomo Biasucci,Sabina Zambon,Anna Rita Roscini,Chiara Trenti,Marcello Arca,Massimo Federici,Maria Del Ben,Andrea Bartuli,Andrea Giaccari,Antonio Pipolo,Nadia Citroni,Ornella Guardamagna,Katia Bonomo,Andrea Benso,Gianni Biolo,Lorenzo Maroni,Alessandro Lupi,Luca Bonanni,Maria Grazia Zenti,Kota Matsuki,Mika Hori,Masatsune Ogura,Daisaku Masuda,Takuya Kobayashi,Kumiko Nagahama,Mohammed Al-Jarallah,Mirjana Radovic,Olga Lunegova,Erkayim Bektasheva,Elyor Khodzhiboboev,Andrejs Erglis,Dainus Gilis,Georgijs Nesterovics,Vita Saripo,Ruta Meiere,Arta Upena-RozeMicena,Elizabete Terauda,Selim Jambart,Petra E. Khoury,Sandy Elbitar,Carine Ayoub,Youmna Ghaleb,Urte Aliosaitiene,Sandra Kutkiene,Noor Alicezah Mohd Kasim,Noor Shafina Mohd Nor,Anis Safura Ramli,Suraya Abdul Razak,Alyaa Al-Khateeb,Siti Hamimah Sheikh Abdul Kadir,Suhaila Abd Muid,Thuhairah Hasrah Abdul Rahman,Sazzli Kasim,Ahmad Bakhtiar Md Radzi,Khairul Shafiq Ibrahim,Salmi Razali,Zaliha Ismail,Rohana Abdul Ghani,Muhammad I.A. Hafidz,Ang L. Chua,Marshima M. Rosli,Muthukkaruppan Annamalai,Lay K. Teh,Rafezah Razali,Yung A. Chua,Azhari Rosman,Abdul Rais Sanusi,Nor A.A. Murad,A. Rahman A. Jamal,S.A. Nazli,Aimi Z. Razman,Norhidayah Rosman,Radzi Rahmat,Nur S. Hamzan,C. Azzopardi,Roopa Mehta,Alexandro J. Martagon,Gabriela A.G. Ramirez,Neftali E.A. Villa,Arsenio V. Vazquez,Daniel Elías-López,Gustavo G. Retana,Betsabel Rodriguez,Jose J.C. Macías,Alejandro R. Zazueta,Rocio M. Alvarado,Julieta D.M. Portano,Humberto A. Lopez,Leobardo Sauque-Reyna,Laura G.G. Herrera,Luis E.S. Mendia,Humberto Garcia Aguilar,Elizabeth R. Cooremans,Berenice P. Aparicio,Victoria M. Zubieta,Perla A.C. Gonzalez,Aldo Ferreira-Hermosillo,Nacu C. Portilla,Guadalupe J. Dominguez,Alinna Y.R. Garcia,Hector E.A. Cazares,Jesus R. Gonzalez,Carla V.M. Valencia,Francisco G. Padilla,Ramon M. Prado,Manuel O. De los Rios Ibarra,Ruy D Arjona Villicaña,Karina J.A. Rivera,Ricardo A. Carrera,Jose A. Alvarez,Jose C.A. Martinez,Manuel de los Reyes Barrera Bustillo,Gonzalo C. Vargas,Roberto C. Chacon,Mario H.F. Andrade,Ashanty F. Ortega,Hector G. Alcala,Laura E.G. de Leon,Berenice G. Guzman,Jose J.G. Garcia,Juan C.G. Cuellar,José Ramiro Cruz,Anell Hernandez Garcia,Jesus R.H. Almada,Ursulo J. Herrera,Fabiola L. Sobrevilla,Eduardo M. Rodriguez,Cristina M. Sibaja,Alma B.M. Rodriguez,Jose C.M. Oyervides,Daniel I.P. Vazquez,Eduardo A.R. Rodriguez,Ma L.R. Osorio,Juan R. Saucedo,Margarita T. Tamayo,Luis A.V. Talavera,Luis E.V. Arroyo,Eloy A.Z. Carrillo,Alphonsus Isara,Darlington E. Obaseki,Khalid Al-Waili,Fahad Al-Zadjali,Ibrahim Al-Zakwani,Mohammed Al-Kindi,Suad Al-Mukhaini,Hamida Al-Barwani,Asim Rana,Lahore S.U. Shah,Ewa Starostecka,Agnieszka Konopka,Joanna Lewek,Marcin A. Bartlomiejczyk,Mariusz Gąsior,Krzysztof Dyrbuś,Jacek Jóźwiak,Marcin Gruchała,Marcin Pajkowski,Marzena Romanowska-Kocejko,Marta Żarczyńska-Buchowiecka,Magdalena Chmara,Bartosz Wasąg,Aleksandra Parczewska,Natasza Gilis-Malinowska,Justyna Borowiec-Wolna,Aneta Stróżyk,Marlena Woś,Aleksandra Michalska-Grzonkowska,Ana M. Medeiros,Ana C. Alves,Francisco Silva,Goreti Lobarinhas,Isabel Palma,Jose P. de Moura,Miguel T. Rico,Quitéria Rato,Patrícia Pais,Susana Correia,Oana Moldovan,Maria J. Virtuoso,Jose M. Salgado,Ines Colaço,Andreea Dumitrescu,Calin Lengher,Svetlana Mosteoru,Alexey Meshkov,Alexandra Ershova,Tatiana Rozkova,Victoria Korneva,Kuznetsova T. Yu,Vitaliy Zafiraki,Mikhail Voevoda,Victor Gurevich,Dmitry Duplyakov,Yulia Ragino,Maya Safarova,Igor Shaposhnik,Fahmi Alkaf,Alia Khudari,Nawal Rwaili,Faisal A. Al-Allaf,Mohammad Alghamdi,Mohammed A. Batais,Turky H. Almigbal,Abdulhalim Jamal Kinsara,Ashraf H.A. AlQudaimi,Zuhier Awan,Omer A. Elamin,Hani Altaradi,Natasa Rajkovic,Ljiljana Popovic,Sandra Singh,Ljubica Stosic,Iva Rasulic,N. Lalic,Carolyn S.P. Lam,Tan J. Le,Eric L.T. Siang,Sanjaya Dissanayake,Justin T. I-Shing,Tai E. Shyong,Terrance C.S. Jin,Karin Balinth,Ingrid Buganova,Lubomira Fabryova,Michaela Kadurova,Alexander Klabnik,Miriam Kozárová,Jana Sirotiakova,Tadej Battelino,Jernej Kovac,Matej Mlinaric,Ursa Sustar,Katarina T. Podkrajsek,Zlatko Fras,Borut Jug,Matija Cevc,Gillian J. Pilcher,Dirk J. Blom,K.H. Wolmarans,B.C. Brice,Ovidio Muñiz-Grijalvo,José Luis Díaz-Díaz,Leopoldo Pérez de Isla,Francisco Fuentes,Lina Badimon,François Martin,Angela Lux,Nien-Tzu Chang,Poranee Ganokroj,Mehmet Akbulut,Gökhan Alici,Fahri Bayram,Levent H. Can,Ahmet Celik,Ceyhun Ceyhan,Fatma Y. Coskun,Mesut Demir,Sabri Demircan,Volkan Dogan,Emre Durakoglugil,Ibrahim E. Dural,Omer Gedikli,Aysa Hacioglu,Muge Ildizli,Salih Kilic,Bahadir Kirilmaz,Merih Kutlu,Aytekin Oguz,Oner Ozdogan,Ersel Onrat,Savas Ozer,Tevfik Sabuncu,Tayfun Sahin,Fatih Sivri,Alper Sonmez,Ahmet Temizhan,Selim Topcu,Abdullah Tuncez,Mirac Vural,Mustafa Yenercag,Dilek Yesilbursa,Zerrin Yigit,Aytul B. Yildirim,Aylin Yildirir,Mehmet B. Yilmaz,Bassam Atallah,Mahmoud Traina,Hani Sabbour,Dana A. Hay,Neama Luqman,Abubaker Elfatih,Arshad Abdulrasheed,See Kwok,Nicolas D. Oca,Ximena Reyes,Rano B. Alieva,Ravshanbek D. Kurbanov,Shavkat U. Hoshimov,Ulugbek I. Nizamov,Adolat V. Ziyaeva,Guzal J. Abdullaeva,Doan L. Do,Mai N.T. Nguyen,Ngoc T. Kim,Thanh T. Le,Hong A. Le,Lale Tokgozoglu,Alberico L. Catapano,Kausik K. Ray +723 more
TL;DR: The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterololaemia through harmonisation and pooling of multinational data as discussed by the authors.
Journal ArticleDOI
The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential
Jean-Charles Fruchart,Raul D. Santos,Carlos A. Aguilar-Salinas,Masanori Aikawa,Khalid Al Rasadi,Pierre Amarenco,Philip J. Barter,Richard Ceska,Alberto Corsini,Jean-Pierre Després,Patrick Duriez,Robert H. Eckel,Marat V. Ezhov,Michel Farnier,Henry N. Ginsberg,Michel P. Hermans,Shun Ishibashi,Fredrik Karpe,Tatsuhiko Kodama,Wolfgang Koenig,Wolfgang Koenig,Michel Krempf,Michel Krempf,Soo Lim,Alberto J. Lorenzatti,Ruth McPherson,Jesús Millán Núñez-Cortés,Børge G. Nordestgaard,Børge G. Nordestgaard,Hisao Ogawa,Chris J. Packard,Jorge Plutzky,Carlos I. Ponte-Negretti,Aruna D. Pradhan,Aruna D. Pradhan,Kausik K. Ray,Željko Reiner,Paul M. Ridker,Massimiliano Ruscica,Shaukat Sadikot,Hitoshi Shimano,Piyamitr Sritara,Jane K Stock,Ta-Chen Su,Andrey V. Susekov,André Tartar,Marja-Riitta Taskinen,Alexander Tenenbaum,Alexander Tenenbaum,Lale Tokgozoglu,Brian Tomlinson,Anne Tybjærg-Hansen,Anne Tybjærg-Hansen,Paul Valensi,Michal Vrablík,Walter Wahli,Walter Wahli,Walter Wahli,Gerald F. Watts,Shizuya Yamashita,Koutaro Yokote,Alberto Zambon,Peter Libby +62 more
TL;DR: In this paper, the authors developed a selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) for the treatment of atherogenic dyslipidemia.
Journal ArticleDOI
Efficacy and safety of the coadministration of ezetimibe/simvastatin with fenofibrate in patients with mixed hyperlipidemia
Michel Farnier,Eli M. Roth,Blas Gil-Extremera,Gustavo F. Mendez,Geraldine Macdonell,Constance Hamlin,Inna Perevozskaya,Michael J. Davies,Debra Kush,Yale B. Mitchel +9 more
TL;DR: Coadministration of EZE/SIMVA + FENO effectively improved the overall atherogenic lipid profile of patients with mixed hyperlipidemia.
Journal ArticleDOI
PCSK9: From discovery to therapeutic applications.
TL;DR: A dramatic decrease in LDL-C up to 70% can be obtained with the most efficacious doses, and large phase III programmes are ongoing to evaluate the long-term efficacy and safety of these very promising new agents.