C
Chris Gaiteri
Researcher at Rush University Medical Center
Publications - 67
Citations - 4730
Chris Gaiteri is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Cognitive decline & Dementia. The author has an hindex of 25, co-authored 60 publications receiving 3408 citations. Previous affiliations of Chris Gaiteri include Allen Institute for Brain Science & University of Pittsburgh.
Papers
More filters
Journal ArticleDOI
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
Bin Zhang,Chris Gaiteri,Liviu-Gabriel Bodea,Zhi Wang,Joshua J McElwee,Alexei A. Podtelezhnikov,Chunsheng Zhang,Tao Xie,Linh M. Tran,Radu Dobrin,Eugene M. Fluder,Bruce E. Clurman,Stacey Melquist,Manikandan Narayanan,Christine Suver,Hardik Shah,Milind Mahajan,Tammy Gillis,Jayalakshmi S. Mysore,Marcy E. MacDonald,John Lamb,David A. Bennett,Cliona Molony,David J. Stone,Vilmundur Gudnason,Amanda J. Myers,Eric E. Schadt,Harald Neumann,Jun Zhu,Valur Emilsson +29 more
TL;DR: The causal network structure is a useful predictor of response to gene perturbations and presents a framework to test models of disease mechanisms underlying LOAD.
Journal ArticleDOI
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Sara Mostafavi,Sara Mostafavi,Chris Gaiteri,Sarah E. Sullivan,Charles C. White,Shinya Tasaki,Jishu Xu,Mariko Taga,Mariko Taga,Hans-Ulrich Klein,Hans-Ulrich Klein,Ellis Patrick,Vitalina Komashko,Cristin McCabe,Robert V. Smith,Elizabeth M. Bradshaw,Elizabeth M. Bradshaw,David E. Root,Aviv Regev,Lei Yu,Lori B. Chibnik,Lori B. Chibnik,Julie A. Schneider,Tracy L. Young-Pearse,Tracy L. Young-Pearse,David A. Bennett,Philip L. De Jager,Philip L. De Jager +27 more
TL;DR: The construction and validation of a molecular network of the aging human frontal cortex is reported, constructed and validated from RNA sequence data from 478 individuals and identified genes that affect cognitive decline or neuropathology in Alzheimer's disease.
Journal ArticleDOI
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
Bernard Ng,Charles C. White,Hans-Ulrich Klein,Hans-Ulrich Klein,Solveig K. Sieberts,Cristin McCabe,Ellis Patrick,Jishu Xu,Lei Yu,Chris Gaiteri,David A. Bennett,Sara Mostafavi,Sara Mostafavi,Philip L. De Jager,Philip L. De Jager +14 more
TL;DR: A multi-omic resource generated by applying quantitative trait locus (xQTL) analyses to RNA sequence, DNA methylation and histone acetylation data from the dorsolateral prefrontal cortex of 411 older adults who have all three data types is reported.
Journal ArticleDOI
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research
Phillip L De Jager,Phillip L De Jager,Yiyi Ma,Cristin McCabe,Jishu Xu,Badri N. Vardarajan,Daniel Felsky,Daniel Felsky,Hans-Ulrich Klein,Hans-Ulrich Klein,Charles C. White,Mette A. Peters,Ben Lodgson,Parham Nejad,Anna Tang,Lara M. Mangravite,Lei Yu,Chris Gaiteri,Sara Mostafavi,Julie A. Schneider,David A. Bennett +20 more
TL;DR: The systematic profiling of the dorsolateral prefrontal cortex obtained from a subset of autopsied individuals enrolled in the Religious Orders Study or the Rush Memory and Aging Project, which are jointly designed prospective studies of aging and dementia with detailed, longitudinal cognitive phenotyping during life and a quantitative, structured neuropathologic examination after death, is initiated.
Journal ArticleDOI
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Solveig K. Sieberts,Thanneer M. Perumal,Minerva M. Carrasquillo,Mariet Allen,Joseph S. Reddy,Gabriel E. Hoffman,Kristen K. Dang,John N. Calley,Phillip J. Ebert,James A. Eddy,Xue Wang,Anna K. Greenwood,Sara Mostafavi,Sara Mostafavi,S Akbarian,J Bendl,M S Breen,K Brennand,L Brown,A Browne,J D Buxbaum,A Charney,Andrew Chess,Couto L,Gregory E. Crawford,Devillers O,Bernie Devlin,Amanda Dobbyn,E Domenici,M Filosi,E Flatow,Nancy Francoeur,John F. Fullard,S E Gil,Kiran Girdhar,A Gulyás-Kovács,R.E. Gur,C G Hahn,Vahram Haroutunian,Mads E. Hauberg,Laura M. Huckins,Rivka Jacobov,Y Jiang,Jessica S. Johnson,Bibi Kassim,Y Kim,Lambertus Klei,Robin Kramer,Mario Lauria,Thomas Lehner,David A. Lewis,Barbara K. Lipska,Kelsey S. Montgomery,R Park,C Rosenbluh,Panagiotis Roussos,Douglas M. Ruderfer,G Senthil,Hardik Shah,Laura G. Sloofman,L Song,E Stahl,P.F. Sullivan,R Visintainer,J Wang,Y C Wang,Jennifer Wiseman,E Xia,W Zhang,Elizabeth Zharovsky,L Addis,S N Addo,David C. Airey,Matthias Arnold,David A. Bennett,Y Bi,K Biber,Colette Blach,E Bradhsaw,Paul Brennan,R Canet-Aviles,S Cao,A Cavalla,Yooree Chae,W W Chen,J Cheng,David A. Collier,J L Dage,Eric B. Dammer,J W Davis,John B. Davis,Derek Drake,D Duong,Brian J. Eastwood,Michelle E. Ehrlich,B Ellingson,B W Engelmann,S Esmaeelinieh,Daniel Felsky,Cory C. Funk,Chris Gaiteri +100 more
TL;DR: A colocalization analysis is applied to identify genes underlying the GWAS association peaks for schizophrenia and identify a potentially novel gene colocalized with lncRNA RP11-677M14.