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Nikos C. Kyrpides
Researcher at Joint Genome Institute
Publications - 735
Citations - 73233
Nikos C. Kyrpides is an academic researcher from Joint Genome Institute. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 96, co-authored 711 publications receiving 62360 citations. Previous affiliations of Nikos C. Kyrpides include University of Crete & Oak Ridge National Laboratory.
Papers
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Journal ArticleDOI
Alive and well at 100
TL;DR: The Genomic Standards Consortium (GSC), with the support of the Michigan State University Foundation and the U.S. Department of Energy, is pleased to announce that it has passed two important milestones and is looking forward to becoming the publication of choice for genome and metagenome articles, SOPs, meeting reports and other articles of interest to the community in the future.
Journal Article
One and two-level regulation patterns affecting NF-kappa B mRNA and nuclear NF-kappa B activity after treatment with TNF-alpha, IFN-gamma and IL-4.
TL;DR: This study employed the well described HL-60 cellular system that expresses constitutively basal amounts of NF-kappa B and is susceptible to NF-Kappa B induction by various biological or chemical agents and witnessed that all three cytokines were able to confer proliferative senescence and down-regulate concomitantly c-myc and NF- kappa B mRNA levels, events chronologically in accord with induction of differentiation.
Patent
Thermostable rna-guided endonucleases and methods of use thereof
TL;DR: In this article, an RNA-guided endonucleases, nucleic acids encoding same, and compositions comprising same were provided. And the present disclosure provides ribonucleoprotein complexes comprising: an RNA guided endonuclease and a guide RNA.
Journal ArticleDOI
Metatranscriptomic Sequencing of a Cyanobacterial Soil-Surface Consortium with and without a Diverse Underlying Soil Microbiome.
Terrence H. Bell,Ryan V. Trexler,Xin Peng,Marcel Huntemann,Alicia Clum,Brian Foster,Bryce Foster,Simon Roux,Krishnaveni Palaniappan,Neha Varghese,Supratim Mukherjee,T. B. K. Reddy,Chris Daum,Alex Copeland,Natalia Ivanova,Nikos C. Kyrpides,Christa Pennacchio,Emiley A. Eloe-Fadrosh,Mary Ann Bruns +18 more
TL;DR: Soil surface consortia are easily observed and sampled, allowing examination of their interactions with soil microbiomes, and metatranscriptomic sequences from Dark Green 1 (DG1) are presented in the presence and absence of an underlying soil microbiome and/or urea.
Journal ArticleDOI
Evolution of a multi-step phosphorelay signal transduction system in Ensifer: recruitment of the sigma factor RpoN and a novel enhancer-binding protein triggers acid-activated gene expression.
Rui Tian,Stephan Heiden,Wan Adnawani Meor Osman,Julie Ardley,Euan K. James,Margaret Gollagher,Ravi Tiwari,Rekha Seshadri,Nikos C. Kyrpides,Wayne Reeve +9 more
TL;DR: A multi‐step phosphorelay signal transduction pathway consisting of TcsA, TcrA, FsrR, RpoN and its cognate enhancer‐binding protein EbpA is characterised, which is required for the induction of lpiA and the downstream acvB gene.