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Paul C. D. Johnson
Researcher at University of Glasgow
Publications - 118
Citations - 8755
Paul C. D. Johnson is an academic researcher from University of Glasgow. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 33, co-authored 103 publications receiving 6614 citations. Previous affiliations of Paul C. D. Johnson include Robertson Centre for Biostatistics & University of London.
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Journal ArticleDOI
The coefficient of determination R2 and intra-class correlation coefficient from generalized linear mixed-effects models revisited and expanded.
TL;DR: This paper generalizes the methods called for Poisson and binomial GLMMs to all other non-Gaussian distributions, in particular to negative binomial and gamma distributions that are commonly used for modelling biological data and can be used across disciplines and regardless of statistical environments.
Journal ArticleDOI
Extension of Nakagawa & Schielzeth's R2GLMM to random slopes models.
TL;DR: It is shown that R2 GLMM can be extended to random slopes models using a simple formula that is straightforward to implement in statistical software and substantially widens the potential application of R2GLMM.
Journal ArticleDOI
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Alisa K. Manning,Alisa K. Manning,Alisa K. Manning,Robert A. Scott,Jonna L. Grimsby,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Han Chen,Denis Rybin,Ching-Ti Liu,Lawrence F. Bielak,Inga Prokopenko,Najaf Amin,Daniel R. Barnes,Gemma Cadby,Gemma Cadby,Jouke-Jan Hottenga,Erik Ingelsson,Anne U. Jackson,Toby Johnson,Stavroula Kanoni,Claes Ladenvall,Vasiliki Lagou,Jari Lahti,Cécile Lecoeur,Cécile Lecoeur,Yongmei Liu,María Teresa Martínez-Larrad,May E. Montasser,Pau Navarro,John R. B. Perry,John R. B. Perry,John R. B. Perry,Laura J. Rasmussen-Torvik,Perttu Salo,Naveed Sattar,Dmitry Shungin,Dmitry Shungin,Rona J. Strawbridge,Toshiko Tanaka,Cornelia M. van Duijn,Ping An,Mariza de Andrade,Jeanette S. Andrews,Thor Aspelund,Mustafa Atalay,Yurii S. Aulchenko,Beverley Balkau,Stefania Bandinelli,Jacques S. Beckmann,John Beilby,Claire Bellis,Richard N. Bergman,John Blangero,Mladen Boban,Michael Boehnke,Eric Boerwinkle,Lori L. Bonnycastle,Dorret I. Boomsma,Ingrid B. Borecki,Yvonne Böttcher,Claude Bouchard,Eric J. Brunner,Danijela Budimir,Harry Campbell,Olga D. Carlson,Peter S. Chines,Robert Clarke,Francis S. Collins,Arturo Corbató-Anchuelo,David Couper,Ulf de Faire,George Dedoussis,Panos Deloukas,Maria Dimitriou,Josephine M. Egan,Gudny Eiriksdottir,Michael R. Erdos,Johan G. Eriksson,Elodie Eury,Elodie Eury,Luigi Ferrucci,Ian Ford,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Maria Grazia Franzosi,Paul W. Franks,Timothy M. Frayling,Philippe Froguel,Pilar Galan,Eco J. C. de Geus,Bruna Gigante,Nicole L. Glazer,Anuj Goel,Leif Groop,Vilmundur Gudnason,Göran Hallmans,Anders Hamsten,Ola Hansson,Tamara B. Harris,Caroline Hayward,Simon Heath,Serge Hercberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Min A. Jhun,Paul C. D. Johnson,J. Wouter Jukema,Antti Jula,Wen Hong L. Kao,Jaakko Kaprio,Jaakko Kaprio,Sharon L.R. Kardia,Sirkka Keinänen-Kiukaanniemi,Mika Kivimäki,Ivana Kolcic,Peter Kovacs,Meena Kumari,Johanna Kuusisto,Kirsten Ohm Kyvik,Markku Laakso,Timo A. Lakka,Lars Lannfelt,G. Mark Lathrop,Lenore J. Launer,Karin Leander,Guo Li,Lars Lind,Jaana Lindström,Stéphane Lobbens,Stéphane Lobbens,Ruth J. F. Loos,Jian'an Luan,Valeriya Lyssenko,Reedik Mägi,Reedik Mägi,Patrik K. E. Magnusson,Michael Marmot,Pierre Meneton,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Iva Miljkovic,Narisu Narisu,Jeffrey R. O'Connell,Ken K. Ong,Ben A. Oostra,Lyle J. Palmer,Lyle J. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,James S. Pankow,John F. Peden,Nancy L. Pedersen,Marina Pehlić,Leena Peltonen,Leena Peltonen,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Marijana Peričić,Markus Perola,Louis Pérusse,Patricia A. Peyser,Ozren Polasek,Peter P. Pramstaller,Michael A. Province,Katri Räikkönen,Rainer Rauramaa,Emil Rehnberg,Kenneth Rice,Jerome I. Rotter,Igor Rudan,Igor Rudan,Aimo Ruokonen,Timo Saaristo,Maria Sabater-Lleal,Veikko Salomaa,David B. Savage,Richa Saxena,Richa Saxena,Peter Schwarz,Udo Seedorf,Bengt Sennblad,Manuel Serrano-Ríos,Alan R. Shuldiner,Eric J.G. Sijbrands,David S. Siscovick,Johannes H. Smit,Kerrin S. Small,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Albert V. Smith,Alena Stančáková,Kathleen Stirrups,Michael Stumvoll,Yan V. Sun,Amy J. Swift,Anke Tönjes,Jaakko Tuomilehto,Stella Trompet,André G. Uitterlinden,Matti Uusitupa,Max Vikström,Veronique Vitart,Marie-Claude Vohl,Benjamin F. Voight,Peter Vollenweider,Gerard Waeber,Dawn M. Waterworth,Hugh Watkins,Hugh Watkins,Eleanor Wheeler,Elisabeth Widen,Sarah H. Wild,Sara M. Willems,Gonneke Willemsen,James F. Wilson,Jacqueline C.M. Witteman,Alan F. Wright,Hanieh Yaghootkar,Diana Zelenika,Tatijana Zemunik,Lina Zgaga,Lina Zgaga,Nicholas J. Wareham,Mark I. McCarthy,Inês Barroso,Inês Barroso,Richard M. Watanabe,Jose C. Florez,Jose C. Florez,José Dupuis,José Dupuis,James B. Meigs,Claudia Langenberg +243 more
TL;DR: Six previously unknown loci associated with fasting insulin at P < 5 × 10−8 in combined discovery and follow-up analyses of 52 studies comprising up to 96,496 non-diabetic individuals are presented.
Journal ArticleDOI
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Robert A. Scott,Vasiliki Lagou,Ryan P. Welch,Eleanor Wheeler,May E. Montasser,Jian'an Luan,Reedik Mägi,Rona J. Strawbridge,Emil Rehnberg,Stefan Gustafsson,Stavroula Kanoni,Laura J. Rasmussen-Torvik,Loic Yengo,Cécile Lecoeur,Dmitry Shungin,Serena Sanna,Carlo Sidore,Paul C. D. Johnson,J. Wouter Jukema,Toby Johnson,Anubha Mahajan,Niek Verweij,Gudmar Thorleifsson,Jouke-Jan Hottenga,Sonia Shah,Albert V. Smith,Bengt Sennblad,Christian Gieger,Perttu Salo,Markus Perola,Nicholas J. Timpson,David M. Evans,Beate St Pourcain,Ying Wu,Jeanette S. Andrews,Jennie Hui,Lawrence F. Bielak,Wei Zhao,Momoko Horikoshi,Pau Navarro,Aaron Isaacs,Jeffrey R. O'Connell,Kathleen Stirrups,Veronique Vitart,Caroline Hayward,Tõnu Esko,Evelin Mihailov,Ross M. Fraser,Tove Fall,Benjamin F. Voight,Soumya Raychaudhuri,Han Chen,Cecilia M. Lindgren,Andrew P. Morris,Nigel W. Rayner,Neil Robertson,Denis Rybin,Ching-Ti Liu,Jacques S. Beckmann,Sara M. Willems,Peter S. Chines,Anne U. Jackson,Hyun Min Kang,Heather M. Stringham,Kijoung Song,Toshiko Tanaka,John F. Peden,Anuj Goel,Andrew A. Hicks,Ping An,Martina Müller-Nurasyid,Anders Franco-Cereceda,Lasse Folkersen,Letizia Marullo,Hanneke Jansen,Albertine J. Oldehinkel,Marcel Bruinenberg,James S. Pankow,Kari E. North,Nita G. Forouhi,Ruth J. F. Loos,Sarah Edkins,Tibor V. Varga,Göran Hallmans,Heikki Oksa,Mulas Antonella,Ramaiah Nagaraja,Stella Trompet,Ian Ford,Stephan J. L. Bakker,Augustine Kong,Meena Kumari,Bruna Gigante,Christian Herder,Patricia B. Munroe,Mark J. Caulfield,Jula Antti,Massimo Mangino,Kerrin S. Small,Iva Miljkovic,Yongmei Liu,Mustafa Atalay,Wieland Kiess,Alan James,Fernando Rivadeneira,André G. Uitterlinden,Colin N. A. Palmer,Alex S. F. Doney,Gonneke Willemsen,Johannes H. Smit,Susan Campbell,Ozren Polasek,Lori L. Bonnycastle,Serge Hercberg,Maria Dimitriou,Jennifer L. Bolton,Gerard R Fowkes,Peter Kovacs,Jaana Lindström,Tatijana Zemunik,Stefania Bandinelli,Sarah H. Wild,Hanneke Basart,Wolfgang Rathmann,Harald Grallert,Winfried Maerz,Marcus E. Kleber,Bernhard O. Boehm,Annette Peters,Peter P. Pramstaller,Michael A. Province,Ingrid B. Borecki,Nicholas D. Hastie,Igor Rudan,Harry Campbell,Hugh Watkins,Martin Farrall,Michael Stumvoll,Luigi Ferrucci,Dawn M. Waterworth,Richard N. Bergman,Francis S. Collins,Jaakko Tuomilehto,Richard M. Watanabe,Eco J. C. de Geus,Brenda W.J.H. Penninx,Albert Hofman,Ben A. Oostra,Bruce M. Psaty,Peter Vollenweider,James F. Wilson,Alan F. Wright,G. Kees Hovingh,Andres Metspalu,Matti Uusitupa,Patrik K. E. Magnusson,Kirsten Ohm Kyvik,Jaakko Kaprio,Jackie F. Price,George Dedoussis,Panos Deloukas,Pierre Meneton,Lars Lind,Michael Boehnke,Alan R. Shuldiner,Cornelia M. van Duijn,Andrew D. Morris,Anke Toenjes,Patricia A. Peyser,John Beilby,John Beilby,Antje Körner,Johanna Kuusisto,Markku Laakso,Stefan R. Bornstein,Peter Schwarz,Timo A. Lakka,Rainer Rauramaa,Linda S. Adair,George Davey Smith,Tim D. Spector,Thomas Illig,Ulf de Faire,Anders Hamsten,Vilmundur Gudnason,Mika Kivimäki,Aroon D. Hingorani,Sirkka Keinänen-Kiukaanniemi,T. Saaristo,Dorret I. Boomsma,Kari Stefansson,Pim van der Harst,Josée Dupuis,Nancy L. Pedersen,Naveed Sattar,Tamara B. Harris,Francesco Cucca,Samuli Ripatti,Veikko Salomaa,Karen L. Mohlke,Beverley Balkau,Philippe Froguel,Anneli Pouta,Marjo-Riitta Järvelin,Nicholas J. Wareham,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Mark I. McCarthy,Paul W. Franks,James B. Meigs,Tanya M. Teslovich,Jose C. Florez,Claudia Langenberg,Erik Ingelsson,Inga Prokopenko,Inês Barroso +216 more
TL;DR: Gene-based analyses identified further biologically plausible loci, suggesting that additional loci beyond those reaching genome-wide significance are likely to represent real associations and further functional analysis of these newly discovered loci will further improve the understanding of glycemic control.
Posted ContentDOI
The coefficient of determination R2 and intra-class correlation coefficient from generalized linear mixed-effects models revisited and expanded
TL;DR: In this paper, a non-Gaussian version of the coefficient of determination (R2GLMM) is proposed for estimating the proportion of variance explained by a statistical model and is an important summary statistic of biological interest.