P
Paul G. Richardson
Researcher at Harvard University
Publications - 1631
Citations - 174221
Paul G. Richardson is an academic researcher from Harvard University. The author has contributed to research in topics: Multiple myeloma & Bortezomib. The author has an hindex of 183, co-authored 1533 publications receiving 155912 citations. Previous affiliations of Paul G. Richardson include Broomfield Hospital & Dartmouth College.
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Journal ArticleDOI
Hematopoietic Cell Transplantation in Patients with Medication-Related Osteonecrosis of the Jaws.
Hani Mawardi,Hani Mawardi,Hani Mawardi,Brett Glotzbecker,Paul G. Richardson,Sook-Bin Woo,Sook-Bin Woo +6 more
TL;DR: A retrospective chart review of HCT in patients with multiple myeloma and MRONJ who underwent HCT between December 2005 and December 2014 suggests that patients with MM and MRonJ who undergo HCT are not at increased risk of developing symptoms associated with theMRONJ site or HCT-related infectious complications, and their MRONj is not worsened by HCT.
Journal ArticleDOI
Biomarker Correlation with Outcomes in Patients with Relapsed or Refractory Multiple Myeloma on a Phase I Study of Everolimus in Combination with Lenalidomide
Andrew Yee,Anuj Mahindra,Paul G. Richardson,Diana Cirstea,Tyler Scullen,Scott J. Rodig,Teru Hideshima,Parameswaran Hari,Jacob P. Laubach,Irene M. Ghobrial,Robert L. Schlossman,Nikhil C. Munshi,Edie Weller,Kenneth C. Anderson,Noopur Raje +14 more
TL;DR: Biomarker data demonstrated that treatment with everolimus and lenalidomide consistently downregulated protein expression of phosphorylated p70S6K, a downstream target of mTOR, in a heavily pretreated population.
Journal ArticleDOI
Isatuximab for relapsed/refractory multiple myeloma: review of key subgroup analyses from the Phase III ICARIA-MM study.
Paul G. Richardson,Simon J. Harrison,Sara Bringhen,Fredrik Schjesvold,Fredrik Schjesvold,Kwee Yong,Frank Campana,Solenn Le-Guennec,Sandrine Macé,Meletios A. Dimopoulos +9 more
TL;DR: In this paper, the anti-CD38 monoclonal antibody isatuximab was added to pomalidomide and dexamethasone to improve progression-free survival and response rates in patients with relapsed/refractory multiple myeloma.
Journal ArticleDOI
Erythropoiesis-Stimulating Agents Do Not Adversely Affect Long-Term Outcomes Nor Increase the Risk of Thromboembolic Events in Multiple Myeloma Patients Treated in the Phase III VISTA Trial.
Paul G. Richardson,Rudolf Schlag,Nuriet K. Khuageva,Meletios A. Dimopoulos,Ofer Shpilberg,Martin Kropff,Michel Delforge,Maria Teresa Petrucci,Victor A Rossiev,Jian Hou,Tadeusz Robak,Maria-Victoria Mateos,Kenneth C. Anderson,Andrew Cakana,Kevin Liu,William Deraedt,Helgi van de Velde,Jesús F. San Miguel +17 more
TL;DR: A post-hoc analysis from a large, well-controlled multicenter phase III trial in frontline MM shows that ESA use did not adversely impact long-term outcomes with VMP or MP, and may be associated with a survival benefit.
Journal ArticleDOI
Safety of Defibrotide (DF) In Stem Cell Transplant (SCT) Patients (Pts).
Selim Corbacioglu,Enric Carreras,Dietger Niederwieser,Marco Sardella,Margaret Hoyle,Robin Hume,Joseph M. Massaro,Alison L. Hannah,Massimo Iacobelli,Paul G. Richardson +9 more
TL;DR: A comprehensive review of safety for DF in this setting, including a review of the contribution of DF to observed toxicities in the initial single-arm trials, found that DF was generally well tolerated.