R
R. Wambutt
Publications - 6
Citations - 1578
R. Wambutt is an academic researcher. The author has contributed to research in topics: Genome project & Gene. The author has an hindex of 6, co-authored 6 publications receiving 1550 citations.
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Journal ArticleDOI
Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana
Michael W. Bevan,Ian Bancroft,E. Bent,K. Love,Howard M. Goodman,Caroline Dean,R. Bergkamp,Wim G. Dirkse,M. van Staveren,Willem J. Stiekema,L. Drost,P. Ridley,S.-A. Hudson,K. Patel,George Murphy,Pietro Piffanelli,H. Wedler,E. Wedler,R. Wambutt,T. Weitzenegger,Thomas Pohl,Nancy Terryn,J. Gielen,R. Villarroel,R. De Clerck,M. Van Montagu,A. Lecharny,S. Auborg,I. Gy,M. Kreis,N. Lao,Tony A. Kavanagh,S. Hempel,P. Kötter,K.-D. Entian,M. Rieger,M. Schaeffer,B. Funk,S. Mueller-Auer,M. Silvey,Richard James,A. Montfort,A. Pons,Pere Puigdomènech,A. Douka,E. Voukelatou,Dimitra Milioni,Polydefkis Hatzopoulos,E. Piravandi,B. Obermaier,H. Hilbert,A. Düsterhöft,T. Moores,Jonathan D. G. Jones,T. Eneva,Klaus Palme,Vladimir Benes,S. Rechman,W. Ansorge,R. Cooke,Claire Berger,Michel Delseny,Marleen Voet,Guido Volckaert,Hans-Werner Mewes,S. Klosterman,C. Schueller,N. Chalwatzis +67 more
TL;DR: Analysis of the sequence revealed an average gene density of one gene every 4.8 kilobases, and 54% of the predicted genes had significant similarity to known genes, and other interesting features were found, such as the sequence of a disease-resistance gene locus, the distribution of retroelements, and the frequent occurrence of clustered gene families.
Journal ArticleDOI
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
Klaus F. X. Mayer,C. Schüller,R. Wambutt,George Murphy,Guido Volckaert,Thomas Pohl,A. Düsterhöft,Willem J. Stiekema,K.-D. Entian,Nancy Terryn,Barbara Harris,Wilhelm Ansorge,Petra Brandt,Leslie A. Grivell,Michael A. Rieger,M. Weichselgartner,V De Simone,B. Obermaier,R. Mache,Mario Müller,M. Kreis,Michel Delseny,Pere Puigdomènech,Martin D. Watson,T. Schmidtheini,B. Reichert,D. Portatelle,Manuel Pérez-Alonso,Marc Boutry,Ian Bancroft,P. Vos,Joerg Hoheisel,Wolfgang Zimmermann,H. Wedler,P. Ridley,S. A. Langham,B. McCullagh,L. Bilham,Johan Robben,J. Van der Schueren,B. Grymonprez,Y. J. Chuang,F. Vandenbussche,M. Braeken,I. Weltjens,Marleen Voet,I. Bastiaens,Rita Aert,E. Defoor,T. Weitzenegger,G. Bothe,U. Ramsperger,H. Hilbert,M. Braun,E. Holzer,A. Brandt,Sander Peters,M. van Staveren,Wim G. Dirkse,P. Mooijman,R. Klein Lankhorst,M. Rose,J. Hauf,P. Kötter,S. Berneiser,S. Hempel,M. Feldpausch,S. Lamberth,H. Van den Daele,A. De Keyser,C. Buysshaert,J. Gielen,R. Villarroel,R. De Clercq,M. Van Montagu,Jane Rogers,A. Cronin,Michael A. Quail,S. Bray-Allen,L. Clark,J. Doggett,S. Hall,M. Kay,Nicola Lennard,K. McLay,R. Mayes,A. Pettett,Marie-Adèle Rajandream,M. Lyne,Vladimir Benes,S. Rechmann,D. Borkova,H. Blöcker,M. Scharfe,M. Grimm,T. H. Löhnert,S. Dose,M. de Haan,A.C. Maarse,M. Schäfer,S Müller-Auer,C. Gabel,M. Fuchs,Berthold Fartmann,K. Granderath,D. Dauner,A. Herzl,Sindy Neumann,Anagnostis Argiriou,D. Vitale,Rosario Liguori,E. Piravandi,O. Massenet,F. Quigley,G. Clabauld,A. Mündlein,R. Felber,S. Schnabl,R. Hiller,W. Schmidt,A. Lecharny,S. Aubourg,F. Chefdor,R. Cooke,C. Berger,A. Montfort,Elena Casacuberta,T. Gibbons,N. Weber,Micheline Vandenbol,M. D. Bargues,Javier Terol,A. Torres,A Perez-Perez,Bénédicte Purnelle,E. Bent,S. Johnson,D. Tacon,T. Jesse,Leo Heijnen,S. Schwarz,Patrik Scholler,Steffen Heber,P. Francs,C. Bielke,Dmitrij Frishman,D. Haase,Kai Lemcke,Hans-Werner Mewes,S. Stocker,P. Zaccaria,Michael W. Bevan,Richard K. Wilson,M. de la Bastide,K. Habermann,L. Parnell,Neilay Dedhia,L. Gnoj,K. Schutz,E. Huang,Lori Spiegel,M. Sehkon,Joseph A. Murray,P. Sheet,Matt Cordes,J. Abu-Threideh,T. Stoneking,Joelle Kalicki,Tina Graves,G. Harmon,Jennifer Edwards,P. Latreille,Laura Courtney,J. Cloud,A. Abbott,Kelsi Scott,David W. Johnson,Patrick Minx,David Bentley,Bob Fulton,N. Miller,T. Greco,K. Kemp,Jason B. Kramer,Lucinda Fulton,Elaine R. Mardis,Mike Dante,Kymberlie H. Pepin,LaDeana W. Hillier,Joanne O. Nelson,John Spieth,E. Ryan,S. Andrews,C. Geisel,Dan Layman,Hui Du,Johar Ali,A. Berghoff,K. Jones,K. Drone,M. Cotton,Corinne E. Joshu,B. Antonoiu,M. Zidanic,Cindy Strong,H. Sun,B. Lamar,C. Yordan,P. Ma,P. Ma,J. Zhong,J. Zhong,R. Preston,D. Vil,M. Shekher,A. Matero,R. Shah,I'k. Swaby,A. O'Shaughnessy,M. Rodriguez,J. Hoffman,S. Till,S. Granat,Nadim Shohdy,A. Hasegawa,Abdul Hameed,M. Lodhi,A. Johnson,A. Johnson,Ellson Y. Chen,Ellson Y. Chen,Marco A. Marra,Robert A. Martienssen,W. R. McCombie +233 more
TL;DR: Analysis of 17.38 megabases of unique sequence, representing about 17% of the Arabidopsis genome, reveals 3,744 protein coding genes, 81 transfer RNAs and numerous repeat elements.
Journal ArticleDOI
Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs
Stefan Wiemann,Bernd Weil,Ruth Wellenreuther,Johannes Gassenhuber,Sabine Glassl,Wilhelm Ansorge,Michael Böcher,Helmut Blöcker,Stefan Bauersachs,Helmut Blum,Jürgen Lauber,A. Düsterhöft,Andreas Beyer,Karl Köhrer,Normann Strack,Hans-Werner Mewes,Birgit Ottenwälder,Brigitte Obermaier,Jens Tampe,Dagmar Heubner,R. Wambutt,Bernhard Korn,Michaela Klein,Annemarie Poustka +23 more
TL;DR: The sequencing and analysis of 500 novel human cDNAs containing the complete protein coding frame were reported, finding a number of genes that either had been completely missed in the analysis of the genomic sequences or had been wrongly predicted.
Journal ArticleDOI
Conservation of Microstructure between a Sequenced Region of the Genome of Rice and Multiple Segments of the Genome of Arabidopsis thaliana
Klaus F. X. Mayer,George Murphy,Renato Tarchini,R. Wambutt,Guido Volckaert,Thomas Pohl,A. Düsterhöft,Willem J. Stiekema,Karl-Dieter Entian,Nancy Terryn,Kai Lemcke,Dirk Haase,Caroline R. Hall,Anne-Marie van Dodeweerd,Scott V. Tingey,Hans-Werner Mewes,Michael W. Bevan,Ian Bancroft +17 more
TL;DR: The results demonstrate that conservation of the genome microstructure can be identified even between monocot and dicot species, and are consistent with the hypothesis that the Arabidopsis genome has undergone multiple duplication events.
Patent
Human dna sequences
Stefan Wiemann,Annemarie Poustka,Ruth Wellenreuther,Helmut Blum,Brigitte Obermaier,Birgit Ottenwaelder,Andre Bahr,Andreas Duesterhoeft,Christoph Koenig,Juergen Lauber,Dagmar Heubner,R. Wambutt,Karl Koehrer,Andreas Beyer,Johann Gassenhuber,Christian Gruber,Norman Strack,H.W. Mewes,Wilhelm Ansorge,Sabine Glassl,Claudia Rittmueller,Thomas Regiert,Helmut Bloecker,Michael Boecher,Klaus Hornischer,Gabriele Nordsiek,Jens Tampe +26 more
TL;DR: In this article, the human cDNA sequence of a clone, the encoded protein sequence of clones, antibodies and variants thereof, are provided, and the disclosed sequence finds application in a number of ways, including use in profiling assays.