R
Rajesh Kumar Soni
Researcher at Columbia University
Publications - 17
Citations - 581
Rajesh Kumar Soni is an academic researcher from Columbia University. The author has contributed to research in topics: GABAB receptor & Homologous recombination. The author has an hindex of 4, co-authored 17 publications receiving 165 citations.
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Journal ArticleDOI
Transferrin Receptor Is a Specific Ferroptosis Marker
Huizhong Feng,Kenji Schorpp,Jenny Jin,Carrie E. Yozwiak,Benjamin G. Hoffstrom,Aubrianna Decker,Presha Rajbhandari,Michael E. Stokes,Hannah G. Bender,Joleen M. Csuka,Pavan S. Upadhyayula,Peter Canoll,Koji Uchida,Rajesh Kumar Soni,Kamyar Hadian,Brent R. Stockwell +15 more
TL;DR: It is found that anti-TfR1 and anti-malondialdehyde adduct antibodies are effective at staining ferroptotic tumor cells in multiple cell culture and tissue contexts.
Journal ArticleDOI
Structure of Geobacter pili reveals secretory rather than nanowire behaviour
Yangqi Gu,Vishok Srikanth,Aldo I. Salazar-Morales,Ruchi Jain,J. Patrick O'Brien,Sophia M. Yi,Rajesh Kumar Soni,Fadel A. Samatey,Sibel Ebru Yalcin,Nikhil S. Malvankar +9 more
TL;DR: In this paper, it was shown that Geobacter sulfurreducens pili can be used to assemble heterodimeric pili, which remain periplasmic under nanowire-producing conditions that require extracellular electron transfer.
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Structure of human GABA B receptor in an inactive state
Jinseo Park,Ziao Fu,Aurel Frangaj,Jonathan Liu,Lidia Mosyak,Tong Shen,Vesna Slavkovich,Kimberly M. Ray,Jaume Taura,Baohua Cao,Yong Geng,Yong Geng,Hao Zuo,Yongjun Kou,Robert A. Grassucci,Shaoxia Chen,Zheng Liu,Xin Lin,Justin P. Williams,William J. Rice,Edward T. Eng,Rick Huang,Rajesh Kumar Soni,Brian Kloss,Zhiheng Yu,Jonathan A. Javitch,Wayne A. Hendrickson,Paul A. Slesinger,Matthias Quick,Joseph H. Graziano,Hongtao Yu,Oliver Fiehn,Oliver B. Clarke,Joachim Frank,Qing R. Fan +34 more
TL;DR: The structure of the GABAB receptor in an inactive state is presented, revealing a latch between the two subunits that locks the transmembrane domain interface, and the presence of large phospholipids that may modulate receptor function.
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Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine.
Maria Scherma,Johanna S. Qvist,Arun Asok,Shao-shan Carol Huang,Paolo Masia,Matteo Deidda,Ya B. Wei,Ya B. Wei,Rajesh Kumar Soni,Walter Fratta,Paola Fadda,Paola Fadda,Eric R. Kandel,Denise B. Kandel,Denise B. Kandel,Philippe A. Melas +15 more
TL;DR: It is demonstrated that a history of synthetic cannabinoid exposure in adolescent animals results in distinct molecular and epigenetic changes following initial exposure to cocaine, which are pronounced in the prefrontal cortex and associated with an enhanced response to cocaine’s stimulatory effects.
Journal ArticleDOI
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
Jen-Wei Huang,Ananya Acharya,Ananya Acharya,Angelo Taglialatela,Tarun S. Nambiar,Raquel Cuella-Martin,Giuseppe Leuzzi,Samuel B. Hayward,Sarah A. Joseph,Gregory J. Brunette,Roopesh Anand,Rajesh Kumar Soni,Nathan L. Clark,Kara A. Bernstein,Petr Cejka,Petr Cejka,Alberto Ciccia +16 more
TL;DR: C17orf53/MCM8IP, an OB-fold containing protein, promotes HR through direct binding and activation of the MCM8-9 helicase complex, which is an essential DNA repair pathway for genomic stability.