R
Ruth H. Walker
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 149
Citations - 10006
Ruth H. Walker is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Chorea & Neuroacanthocytosis. The author has an hindex of 35, co-authored 141 publications receiving 8192 citations. Previous affiliations of Ruth H. Walker include Mount Sinai Hospital & United States Department of Veterans Affairs.
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
Akinobu Suzuki,Sarah A. Stern,Ozlem Bozdagi,George W. Huntley,Ruth H. Walker,Pierre J. Magistretti,Cristina M. Alberini +6 more
TL;DR: It is concluded that astrocyte-neuron lactate transport is required for long-term memory formation, suggesting that lactate import into neurons is necessary for long -term memory.
Journal ArticleDOI
The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures.
Catharine E. Krebs,Siamak Karkheiran,James C. Powell,Mian Cao,Vladimir Makarov,Hossein Darvish,Gilbert Di Paolo,Ruth H. Walker,Ruth H. Walker,Gholam Ali Shahidi,Joseph D. Buxbaum,Pietro De Camilli,Zhenyu Yue,Coro Paisán-Ruiz +13 more
TL;DR: It is concluded that the SYNJ1 mutation identified here is responsible for the EOP phenotype seen in patients probably due to deficiencies in its phosphatase activity and consequent impairment of its synaptic functions, and suggests phosphoinositide metabolism as a novel therapeutic target for Parkinsonism.
Journal ArticleDOI
McLeod neuroacanthocytosis: genotype and phenotype.
Adrian Danek,Justin P. Rubio,Luca Rampoldi,Mengfatt Ho,Carol Dobson-Stone,François Tison,William A. Symmans,Matthias Oechsner,Wolfgang von Kalckreuth,Julie M. Watt,Alastair J. Corbett,Hisham H. M. Hamdalla,Andrew G. Marshall,Ian Sutton,Maria Teresa Dotti,Alessandro Malandrini,Ruth H. Walker,Geoff Daniels,Anthony P. Monaco +18 more
TL;DR: The resemblance of McLeod syndrome with Huntington's disease and with autosomal recessive chorea‐acanthocytosis suggests that the corresponding proteins—XK, huntingtin, and chorein—might belong to a common pathway, the dysfunction of which causes degeneration of the basal ganglia.
Journal Article
Guidelines for the molecular genetics predictive test in Huntington's disease
L. Went.,J. Broholm,Jean Jaques Cassiman,David Craufurd,Arthur Falek,C. Farmer-Little,Michael R. Hayden,R. Kapp,K. Krahnen,A. Martinez-Descals,M. Mol,N. Myrianthopoulos,H. Petit,Kimberly A. Quaid,C. De Somviele,E. Taylor,A. Tyler,Ruth H. Walker,Nancy S. Wexler +18 more