Sung-Min Ahn

TL;DR: This analysis of all classes of somatic mutation across exons, introns and intergenic regions highlights the repertoire of cancer genes and mutational processes operative, and progresses towards a comprehensive account of the somatic genetic basis of breast cancer.

TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

TL;DR: RB1 mutations can be used as a prognostic molecular biomarker for resectable hepatocellular carcinoma and the potential of anti‐FGF19 treatment in patients with liver cirrhosis is investigated.

TL;DR: The first Korean individual genome sequence (SJK) and analysis results indicate that the overall genetic differences among individuals from closely related ethnic groups may be significant and constructing reference genomes for minor socio-ethnic groups will be useful for massive individual genome sequencing.

TL;DR: Flow field-flow fractionation (FlFFF), coupled with mass spectrometry, allows nanoscale size-based fractionation of exosomes and is more applicable to primary cells and stem cells since it requires much less starting material than conventional gel-based separation, in-gel digestion and the MS-MS method.