T
Tara Biagi
Researcher at Broad Institute
Publications - 10
Citations - 3882
Tara Biagi is an academic researcher from Broad Institute. The author has contributed to research in topics: Genome-wide association study & Haplotype. The author has an hindex of 9, co-authored 10 publications receiving 3590 citations.
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Journal ArticleDOI
Genome sequence, comparative analysis and haplotype structure of the domestic dog
Kerstin Lindblad-Toh,Claire M. Wade,Claire M. Wade,Tarjei S. Mikkelsen,Tarjei S. Mikkelsen,Elinor K. Karlsson,Elinor K. Karlsson,David B. Jaffe,Michael Kamal,Michele Clamp,Jean L. Chang,Edward J. Kulbokas,Michael C. Zody,Evan Mauceli,Xiaohui Xie,Matthew Breen,Robert K. Wayne,Elaine A. Ostrander,Chris P. Ponting,Francis Galibert,Douglas Smith,Pieter J. deJong,Ewen F. Kirkness,Pablo Alvarez,Tara Biagi,William Brockman,Jonathan Butler,Chee-Wye Chin,April Cook,James Cuff,Mark J. Daly,Mark J. Daly,David DeCaprio,Sante Gnerre,Manfred Grabherr,Manolis Kellis,Michael Kleber,Carolyne Bardeleben,Leo Goodstadt,Andreas Heger,Christophe Hitte,Lisa Kim,Klaus-Peter Koepfli,Heidi G. Parker,John P. Pollinger,Stephen M. J. Searle,Nathan B. Sutter,Rachael Thomas,Caleb Webber,Jennifer Baldwin,Jennifer Baldwin,Adal Abebe,Amr Abouelleil,Lynne Aftuck,Mostafa Ait-zahra,Tyler Aldredge,Nicole R. Allen,Peter An,Scott Anderson,Claudel Antoine,Harindra Arachchi,Ali Aslam,Laura Ayotte,Pasang Bachantsang,Andrew Barry,Tashi Bayul,Mostafa Benamara,Aaron M. Berlin,Daniel Bessette,Berta Blitshteyn,Toby Bloom,Jason Blye,Leonid Boguslavskiy,Claude Bonnet,Boris Boukhgalter,Adam Brown,Patrick Cahill,Nadia Calixte,Jody Camarata,Yama Cheshatsang,Jeffrey Chu,Mieke Citroen,Alville Collymore,Patrick Cooke,Tenzin Dawoe,Riza M. Daza,Karin Decktor,Stuart DeGray,Norbu Dhargay,Kimberly Dooley,Kathleen Dooley,Passang Dorje,Kunsang Dorjee,Lester Dorris,Noah Duffey,Alan Dupes,Osebhajajeme Egbiremolen,Richard Elong,Jill Falk,Abderrahim Farina,Susan Faro,Diallo Ferguson,Patricia Ferreira,Sheila A. Fisher,Michael Fitzgerald,Karen Foley,Chelsea D. Foley,Alicia Franke,Dennis C. Friedrich,Diane Gage,Manuel Garber,Gary Gearin,Georgia Giannoukos,Tina Goode,Audra Goyette,Joseph Graham,Edward Grandbois,Kunsang Gyaltsen,Nabil Hafez,Daniel S. Hagopian,Birhane Hagos,Jennifer Ruth Sadler Hall,Claire M. Healy,Ryan Hegarty,Tracey Honan,Andrea Horn,Nathan Houde,Leanne Hughes,Leigh Anne Hunnicutt,M. Husby,Benjamin Jester,Charlien Jones,Asha Kamat,Ben Kanga,Cristyn Kells,Dmitry Khazanovich,Alix Chinh Kieu,Peter Kisner,Mayank Kumar,Krista Lance,Thomas E. Landers,Marcia Lara,William H. Lee,Jean-Pierre Leger,Niall J. Lennon,Lisa Leuper,Sarah LeVine,Jinlei Liu,Xiaohong Liu,Yeshi Lokyitsang,Tashi Lokyitsang,Annie Lui,Jan Macdonald,John E. Major,Richard Marabella,Kebede Maru,Charles Matthews,Susan McDonough,Teena Mehta,James Meldrim,Alexandre Melnikov,Louis Meneus,Atanas Mihalev,Tanya Mihova,Karen Hughes Miller,Rachel Mittelman,Valentine Mlenga,Leonidas Mulrain,Glen Munson,Adam Navidi,Jerome Naylor,Tuyen T. Nguyen,Nga Nguyen,Cindy Nguyen,Thu Nguyen,Robert Nicol,Nyima Norbu,Choe Norbu,Nathaniel Novod,Tenchoe Nyima,Peter Olandt,Barry O'Neill,Keith O'Neill,Sahal Osman,Lucien Oyono,Christopher Patti,Danielle Perrin,Pema Phunkhang,Fritz Pierre,Margaret Priest,Anthony Rachupka,Sujaa Raghuraman,Rayale Rameau,Verneda Ray,Christina Raymond,Filip Rege,Cecil Rise,Julie Rogers,Peter Rogov,Julie Sahalie,Sampath Settipalli,Ted Sharpe,Terrance Shea,Mechele Sheehan,Ngawang Sherpa,Jianying Shi,Diana M. Shih,Jessie Sloan,Cherylyn Smith,Todd Sparrow,John Stalker,Nicole Stange-Thomann,Sharon Stavropoulos,Catherine Stone,Sabrina M. Stone,Sean M. Sykes,Pierre Tchuinga,Pema Tenzing,Senait Tesfaye,Dawa Thoulutsang,Yama Thoulutsang,Kerri Topham,Ira Topping,Tsamla Tsamla,Helen Vassiliev,Vijay Venkataraman,Andy Vo,Tsering Wangchuk,Tsering Wangdi,Michael Weiand,Jane E. Wilkinson,Adam Wilson,Shailendra Yadav,Shuli Yang,Xiaoping Yang,Geneva Young,Qing Yu,Joanne Zainoun,Lisa Zembek,Andrew Zimmer,Eric S. Lander,Eric S. Lander +241 more
TL;DR: A high-quality draft genome sequence of the domestic dog is reported, together with a dense map of single nucleotide polymorphisms (SNPs) across breeds, to shed light on the structure and evolution of genomes and genes.
Journal ArticleDOI
Genome sequence, comparative analysis, and population genetics of the domestic horse.
Claire M. Wade,Elena Giulotto,Snaevar Sigurdsson,Monica Zoli,Sante Gnerre,Freyja Imsland,Teri L. Lear,David L. Adelson,Ernest Bailey,Rebecca R. Bellone,Helmut Blöcker,Ottmar Distl,Robert C. Edgar,Manuel Garber,Tosso Leeb,Evan Mauceli,James N. MacLeod,Maria Cecilia T. Penedo,Joy M. Raison,Ted Sharpe,J. Vogel,Leif Andersson,Douglas F. Antczak,Tara Biagi,Matthew M. Binns,Bhanu P. Chowdhary,S.J. Coleman,G. Della Valle,Sarah Fryc,Gérard Guérin,T. Hasegawa,Emmeline W. Hill,Jerzy Jurka,Anna Kiialainen,Gabriella Lindgren,Jinze Liu,Elisa Magnani,James R. Mickelson,James D. Murray,Solomon G. Nergadze,Robert C. Onofrio,S. Pedroni,M. F. Piras,Terje Raudsepp,Mariano Rocchi,K. H. Røed,Oliver A. Ryder,S. Searle,Loren C. Skow,June E Swinburne,Ann-Christine Syvänen,Teruaki Tozaki,Stephanie J. Valberg,Mark Vaudin,Jared White,Michael C. Zody,Eric S. Lander,Kerstin Lindblad-Toh +57 more
TL;DR: The analysis reveals an evolutionarily new centromere on equine chromosome 11 that displays properties of an immature but fully functioning Centromere and is devoid of centromeric satellite sequence, suggesting thatCentromeric function may arise before satellite repeat accumulation.
Journal ArticleDOI
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis
Tomoyuki Awano,Gary S. Johnson,Claire M. Wade,Martin L. Katz,Gayle C. Johnson,Jeremy F. Taylor,Michele Perloski,Tara Biagi,Izabella Baranowska,Sam Long,Philip A. March,Natasha J. Olby,G. Diane Shelton,Shahnawaz Khan,Dennis P. O'Brien,Kerstin Lindblad-Toh,Joan R. Coates +16 more
TL;DR: These findings identify canine DM to be the first recognized spontaneously occurring animal model for ALS.
Journal ArticleDOI
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
Elinor K. Karlsson,Elinor K. Karlsson,Snaevar Sigurdsson,Snaevar Sigurdsson,Emma L. Ivansson,Emma L. Ivansson,Rachael Thomas,Ingegerd Elvers,Ingegerd Elvers,Jason Wright,Cédric Howald,Noriko Tonomura,Noriko Tonomura,Michele Perloski,Ross Swofford,Tara Biagi,Sarah Fryc,Nathan Anderson,Celine Courtay-Cahen,Lisa Youell,Sally L. Ricketts,Sarah A. Mandlebaum,Patricio Rivera,Henrik von Euler,William C. Kisseberth,Cheryl A. London,Eric S. Lander,Guillermo Couto,Kenine E. Comstock,Mike Starkey,Jaime F. Modiano,Matthew Breen,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh +33 more
TL;DR: Mapping a complex cancer in multiple dog breeds reveals a polygenic spectrum of germline risk factors pointing to specific pathways as drivers of disease.
Journal ArticleDOI
Mammary tumor development in dogs is associated with BRCA1 and BRCA2.
Patricio Rivera,Malin Melin,Tara Biagi,Tove Fall,Jens Häggström,Kerstin Lindblad-Toh,Henrik von Euler +6 more
TL;DR: It is indicated that BRCA1 and BRCa2 contribute to the risk of CMT in ESS, suggesting that dogs may serve as a good model for human breast cancer.