Valeri N. Karamychev

TL;DR: Phylogenetic analyses, comparison of gene content across the group, and reconstruction of ancestral gene sets indicate a combination of extensive gene loss and key gene acquisitions via horizontal gene transfer during the coevolution of lactic acid bacteria with their habitats.

TL;DR: Deletion of genomic regions allows bifidobacteria to adapt to fermentation environments in a very rapid manner and the concomitant loss of possible competitive abilities in the gut.

TL;DR: Comparative analysis of the two phage genomes shows that the area around the triplex-forming elements is enriched in mutational variations, suggesting that in vitro, phage R-Y sequences form triplexes and block DNA synthesis by Taq DNA polymerase in orientation-dependent manner.

TL;DR: Data indicate accumulating mutations in commercial L. acidophilus strains that warrant further study of the effect of damaged genes on the competitiveness of these bacteria in gut microbiota.