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Wen-Cai Ye
Researcher at Jinan University
Publications - 551
Citations - 10678
Wen-Cai Ye is an academic researcher from Jinan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 41, co-authored 485 publications receiving 7917 citations. Previous affiliations of Wen-Cai Ye include Chinese Ministry of Education & Second Military Medical University.
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Techniques for extraction and isolation of natural products: a comprehensive review
TL;DR: This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products, presenting the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.
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Autophagy and multidrug resistance in cancer
Ying-Jie Li,Yu-He Lei,Nan Yao,Chen-Ran Wang,Nan Hu,Wen-Cai Ye,Dong-Mei Zhang,Zhe-Sheng Chen,Zhe-Sheng Chen +8 more
TL;DR: In this paper, the authors summarize advanced studies of autophagy in multidrug resistance (MDR) tumors, including the variable role of auto-gathering in MDR cancer cells.
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Antiviral flavonoids from the root bark of Morus alba L.
TL;DR: A prenylated flavonoid, moralbanone, along with seven known compounds, including leachianone G and alpha-acetyl-amyrin, were isolated from the root bark of Morus alba L and showed potent antiviral activity and weak activity against herpes simplex type 1 virus.
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Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway
Dong-Mei Zhang,Jun-Shan Liu,Lijuan Deng,Minfeng Chen,Anita Yiu,Hui-Hui Cao,Hai-Yan Tian,Kwok-Pui Fung,Hiroshi Kurihara,Jing-Xuan Pan,Wen-Cai Ye +10 more
TL;DR: The underlying antineoplastic mechanisms of arenobufagin that involve cross talk between apoptosis and autophagy via inhibition of the PI3K/Akt/mTOR pathway are elucidated.
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Betulinic Acid and its Derivatives as Potential Antitumor Agents
Dong-Mei Zhang,Hong-Gui Xu,Lei Wang,Ying-Jie Li,Ping-Hua Sun,Xiaoming Wu,Guangji Wang,Wei-Min Chen,Wen-Cai Ye +8 more
TL;DR: This review critically describes the recent research on isolation, synthesis, and derivatization of BA and its natural analogs betulin and 23‐hydroxybetulinic acid and focuses on the current knowledge of antitumor properties, combination treatments, and pharmacological mechanisms of these compounds.