Showing papers by "Ford Motor Company published in 2014"

Evaluating metal–organic frameworks for natural gas storage

Abstract: Metal–organic frameworks have received significant attention as a new class of adsorbents for natural gas storage; however, inconsistencies in reporting high-pressure adsorption data and a lack of comparative studies have made it challenging to evaluate both new and existing materials. Here, we briefly discuss high-pressure adsorption measurements and review efforts to develop metal–organic frameworks with high methane storage capacities. To illustrate the most important properties for evaluating adsorbents for natural gas storage and for designing a next generation of improved materials, six metal–organic frameworks and an activated carbon, with a range of surface areas, pore structures, and surface chemistries representative of the most promising adsorbents for methane storage, are evaluated in detail. High-pressure methane adsorption isotherms are used to compare gravimetric and volumetric capacities, isosteric heats of adsorption, and usable storage capacities. Additionally, the relative importance of increasing volumetric capacity, rather than gravimetric capacity, for extending the driving range of natural gas vehicles is highlighted. Other important systems-level factors, such as thermal management, mechanical properties, and the effects of impurities, are also considered, and potential materials synthesis contributions to improving performance in a complete adsorbed natural gas system are discussed.

Stochastic MPC With Learning for Driver-Predictive Vehicle Control and its Application to HEV Energy Management

Abstract: This paper develops an approach for driver-aware vehicle control based on stochastic model predictive control with learning (SMPCL). The framework combines the on-board learning of a Markov chain that represents the driver behavior, a scenario-based approach for stochastic optimization, and quadratic programming. By using quadratic programming, SMPCL can handle, in general, larger state dimension models than stochastic dynamic programming, and can reconfigure in real-time for accommodating changes in driver behavior. The SMPCL approach is demonstrated in the energy management of a series hybrid electrical vehicle, aimed at improving fuel efficiency while enforcing constraints on battery state of charge and power. The SMPCL controller allocates the power from the battery and the engine to meet the driver power request. A Markov chain that models the power request dynamics is learned in real-time to improve the prediction capabilities of model predictive control (MPC). Because of exploiting the learned pattern of the driver behavior, the proposed approach outperforms conventional model predictive control and shows performance close to MPC with full knowledge of future driver power request in standard and real-world driving cycles.

Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

Abstract: Immune-based therapies for cancer are generating substantial interest because of the success of immune checkpoint inhibitors. This study aimed to enhance anticancer immunity by exploiting the capacity of dendritic cells (DCs) to initiate T cell immunity by efficient uptake and presentation of endocytosed material. Delivery of tumor-associated antigens to DCs using receptor-specific monoclonal antibodies (mAbs) in the presence of DC-activating agents elicits robust antigen-specific immune responses in preclinical models. DEC-205 (CD205), a molecule expressed on DCs, has been extensively studied for its role in antigen processing and presentation. CDX-1401 is a vaccine composed of a human mAb specific for DEC-205 fused to the full-length tumor antigen NY-ESO-1. This phase 1 trial assessed the safety, immunogenicity, and clinical activity of escalating doses of CDX-1401 with the Toll-like receptor (TLR) agonists resiquimod (TLR7/8) and Hiltonol (poly-ICLC, TLR3) in 45 patients with advanced malignancies refractory to available therapies. Treatment induced humoral and cellular immunity to NY-ESO-1 in patients with confirmed NY-ESO-1–expressing tumors across various dose levels and adjuvant combinations. No dose-limiting or grade 3 toxicities were reported. Thirteen patients experienced stabilization of disease, with a median duration of 6.7 months (range, 2.4+ to 13.4 months). Two patients had tumor regression (~20% shrinkage in target lesions). Six of eight patients who received immune-checkpoint inhibitors within 3 months after CDX-1401 administration had objective tumor regression. This first-in-human study of a protein vaccine targeting DCs demonstrates its feasibility, safety, and biological activity and provides rationale for combination immunotherapy strategies including immune checkpoint blockade.

In situ DRIFTS and temperature-programmed technology study on NH3-SCR of NOx over Cu-SSZ-13 and Cu-SAPO-34 catalysts

Abstract: In situ diffuse reflectance infrared Fourier transform spectroscopy (In situ DRIFTS), temperature-programmed desorption (TPD), and temperature-programmed surface reactions (TPSR) were employed to investigate the adsorption and reactive properties of Cu-SSZ-13 and Cu-SAPO-34 zeolite catalysts; these fully formulated washcoat cordierite monoliths were hydrothermally treated at 750 °C in the simulated feed gases. The intrinsic mechanism and reasons for the differences in NH3-SCR activity were proposed based on the characterization results. The in situ DRIFTS and TPD results showed that ammonia could adsorb on both the Lewis and Bronsted acidic sites on these two catalysts; the ammonia on the Bronsted acidic sites might be active in the NH3-SCR reaction. For the different NOx adsorption processes, the total NOx desorption levels followed the following sequence: NO

Cloud-Based Velocity Profile Optimization for Everyday Driving: A Dynamic-Programming-Based Solution

Abstract: Driving style, road geometry, and traffic conditions have a significant impact on vehicles' fuel economy. In general, drivers are not aware of the optimal velocity profile for a given route. Indeed, the global optimal velocity trajectory depends on many factors, and its calculation requires intensive computations. In this paper, we discuss the optimization of the speed trajectory to minimize fuel consumption and communicate it to the driver. With this information the driver can adjust his/her speed profile to reduce the overall fuel consumption. We propose to perform the computation-intensive calculations on a distinct computing platform called the “cloud.” In our approach, the driver sends the information of the intended travel destination to the cloud. In the cloud, the server generates a route, collects the associated traffic and geographical information, and solves the optimization problem by a spatial domain dynamic programming (DP) algorithm that utilizes accurate vehicle and fuel consumption models to determine the optimal speed trajectory along the route. Then, the server sends the speed trajectory to the vehicle where it is communicated to the driver. We tested the approach on a prototype vehicle equipped with a visual interface mounted on the dash of a test vehicle. The test results show 5%-15% improvement in fuel economy depending on the driver and route without a significant effect on the travel time. Although this paper implements the speed advisory system in a conventional vehicle, the solution is generic, and it is applicable to any kind of powertrain structure.

Characteristic Study and Time-Domain Discrete- Wavelet-Transform Based Hybrid Detection of Series DC Arc Faults

Abstract: DC arc fault introduces major safety concerns in a wide variety of components in dc networks However, the randomness and instability of dc arc makes it difficult to be detected In this paper, an experimental system was designed and tested at different load current, dc source voltage, and gap length to evaluate the impact of each parameter to the dc arc Based on the experimental results, characteristics in the electrical behavior were studied and fault detection oriented analysis was conducted A detection algorithm utilizing both time and time-frequency domain characteristics was proposed to differentiate between dc arc fault and normal condition The detection algorithm was then realized on a digital signal processing board and tested to verify the effectiveness Experimental results show that the proposed algorithm can detect arc fault in a timely manner and is free of nuisance trip from normal circuit operations such as load change condition

A tube-based robust nonlinear predictive control approach to semiautonomous ground vehicles

Abstract: This paper proposes a robust control framework for lane-keeping and obstacle avoidance of semiautonomous ground vehicles. It presents a systematic way of enforcing robustness during the MPC design stage. A robust nonlinear model predictive controller (RNMPC) is used to help the driver navigating the vehicle in order to avoid obstacles and track the road centre line. A force-input nonlinear bicycle vehicle model is developed and used in the RNMPC control design. A robust invariant set is used in the RNMPC design to guarantee that state and input constraints are satisfied in the presence of disturbances and model error. Simulations and experiments on a vehicle show the effectiveness of the proposed framework.

Display system utilizing vehicle and trailer dynamics

Abstract: A display system for a vehicle and trailer is disclosed The system comprises an interface configured to receive a directional input and a controller in communication with the interface and a screen The controller is operable to receive a hitch angle and determine a heading direction of the trailer The controller is further operable to determine a predicted heading of the vehicle aligned with the trailer based on the hitch angle The predicted heading of the trailer is then displayed by the controller on the screen

Fault handling in an autonomous vehicle

Abstract: Data is collected during operation of a vehicle. A determination is made that a confidence assessment of at least one of the data indicates at least one fault condition. A first autonomous operation affected by the fault condition is discontinued, where a second autonomous operation that is unaffected by the fault condition is continued.

Secondary organic aerosol formation exceeds primary particulate matter emissions for light-duty gasoline vehicles

Abstract: . The effects of photochemical aging on emissions from 15 light-duty gasoline vehicles were investigated using a smog chamber to probe the critical link between the tailpipe and ambient atmosphere. The vehicles were recruited from the California in-use fleet; they represent a wide range of model years (1987 to 2011), vehicle types and emission control technologies. Each vehicle was tested on a chassis dynamometer using the unified cycle. Dilute emissions were sampled into a portable smog chamber and then photochemically aged under urban-like conditions. For every vehicle, substantial secondary organic aerosol (SOA) formation occurred during cold-start tests, with the emissions from some vehicles generating as much as 6 times the amount of SOA as primary particulate matter (PM) after 3 h of oxidation inside the chamber at typical atmospheric oxidant levels (and 5 times the amount of SOA as primary PM after 5 × 106 molecules cm−3 h of OH exposure). Therefore, the contribution of light-duty gasoline vehicle exhaust to ambient PM levels is likely dominated by secondary PM production (SOA and nitrate). Emissions from hot-start tests formed about a factor of 3–7 less SOA than cold-start tests. Therefore, catalyst warm-up appears to be an important factor in controlling SOA precursor emissions. The mass of SOA generated by photooxidizing exhaust from newer (LEV2) vehicles was a factor of 3 lower than that formed from exhaust emitted by older (pre-LEV) vehicles, despite much larger reductions (a factor of 11–15) in nonmethane organic gas emissions. These data suggest that a complex and nonlinear relationship exists between organic gas emissions and SOA formation, which is not surprising since SOA precursors are only one component of the exhaust. Except for the oldest (pre-LEV) vehicles, the SOA production could not be fully explained by the measured oxidation of speciated (traditional) SOA precursors. Over the timescale of these experiments, the mixture of organic vapors emitted by newer vehicles appears to be more efficient (higher yielding) in producing SOA than the emissions from older vehicles. About 30% of the nonmethane organic gas emissions from the newer (LEV1 and LEV2) vehicles could not be speciated, and the majority of the SOA formed from these vehicles appears to be associated with these unspeciated organics. By comparing this study with a companion study of diesel trucks, we conclude that both primary PM emissions and SOA production for light-duty gasoline vehicles are much greater than for late-model (2007 and later) on-road heavy-duty diesel trucks.

The prevalence of metabolic syndrome in patients with hidradenitis suppurativa

Abstract: Background Metabolic syndrome is a multifaceted disorder strongly associated with increased risk for development of cardiovascular disease. Chronic inflammatory diseases have been associated with metabolic syndrome. Hidradenitis suppurativa is a chronic inflammatory skin disease with significant physical and emotional sequelae. Objective We sought to investigate a possible association between hidradenitis suppurativa and metabolic syndrome. Methods A retrospective chart review of all dermatology clinic encounters over an 18-month period identified 366 patients with an appropriate diagnosis of hidradenitis suppurativa. A control population was created from patients seen in the same clinic during the same time period for the diagnoses of either keloids or verruca vulgaris using the matching criteria of age ±5 years, race, and gender. All participants were examined for characteristics of the metabolic syndrome as defined by the National Cholesterol Education Program Adult Treatment Program III guidelines. Results The prevalence of metabolic syndrome in patients with hidradenitis suppurativa was 50.6%, which was significantly higher than the control group at 30.2% (P Limitations This was a retrospective review. Some participants could not be analyzed for metabolic syndrome presence as a result of missing data points. Conclusion Our results indicate that patients with hidradenitis suppurativa may be at high risk for metabolic syndrome.

Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies.

Abstract: BACKGROUND Treatments for papulopustular rosacea (PPR) are limited. OBJECTIVE To demonstrate the efficacy and safety of once-daily ivermectin 1% cream in subjects with moderate to severe PPR. METHODS Two identically designed, randomized, double-blind, controlled studies of ivermectin 1% cream (IVM 1%) or vehicle once daily for 12 weeks were conducted in subjects with moderate to severe PPR. Efficacy assessments were Investigator's Global Assessment (IGA) of disease severity and inflammatory lesion counts. Safety assessments included incidence of adverse events (AEs) and local tolerance parameters. Subjects evaluated their rosacea and completed satisfaction and quality of life (QoL) questionnaires. RESULTS In both studies, a greater proportion of subjects in the IVM 1% group achieved treatment success (IGA "clear" or "almost clear"): 38.4% and 40.1% vs 11.6% and 18.8% for vehicle (both P<.001), respectively. Ivermectin was superior to vehicle in terms of reduction from baseline in inflammatory lesion counts (76.0% and 75.0% vs 50.0% for both vehicle groups, respectively). For all endpoints, starting at week 4 and continuing through week 12, IVM 1% was statistically significantly superior (P<.001). Fewer subjects treated by IVM 1% reported dermatologic AEs, and a higher proportion of subjects were observed to have no skin dryness or itching compared to vehicle. Significantly more subjects receiving IVM 1% reported having an "excellent" or "good" improvement, along with an improved QoL. CONCLUSION Ivermectin 1% cream was effective and safe in treating inflammatory lesions of papulopustular rosacea.

Emotive engine and method for generating a simulated emotion for an information system

Abstract: Information about a device may be emotively conveyed to a user of the device. Input indicative of an operating state of the device may be received. The input may be transformed into data representing a simulated emotional state. Data representing an avatar that expresses the simulated emotional state may be generated and displayed. A query from the user regarding the simulated emotional state expressed by the avatar may be received. The query may be responded to.

Laser Assisted Drug Delivery: A Review of An Evolving Technology

Abstract: Background Topically applied drugs have a relatively low cutaneous bioavailability. Objective This article reviews the existing applications of laser assisted drug delivery, a means by which the permeation of topically applied agents can be enhanced into the skin. Results The existing literature suggests that lasers are a safe and effective means of enhancing the delivery of topically applied agents through the skin. The types of lasers most commonly studied in regards to drug delivery are the carbon dioxide (CO2) and erbium:yttrium-aluminum-garnet (Er:YAG) lasers. Both conventional ablative and fractional ablative modalities have been utilized and are summarized herein. Limitations The majority of the existing studies on laser assisted drug delivery have been performed on animal models and additional human studies are needed. Conclusions Laser assisted drug delivery is an evolving technology with potentially broad clinical applications. Multiple studies demonstrate that laser pretreatment of the skin can increase the permeability and depth of penetration of topically applied drug molecules for both local cutaneous and systemic applications. Lasers Surg. Med. 46:249–262, 2014. © 2014 Wiley Periodicals, Inc.

Autonomous control in a dense vehicle environment

Abstract: A computer in a first vehicle is programmed to receive a first set of data from at least one sensor in the first vehicle and to receive a second set of data from at least one second vehicle. The second set of data is from at least one sensor in the at least one second vehicle. The computer is further programmed to use both the first set of data and the second set of data to identify at least one feature of a road being traversed by the first vehicle.

Passive sampling methods for contaminated sediments: Practical guidance for selection, calibration, and implementation

Abstract: This article provides practical guidance on the use of passive sampling methods (PSMs) that target the freely dissolved concentration (Cfree) for improved exposure assessment of hydrophobic organic chemicals in sediments. Primary considerations for selecting a PSM for a specific application include clear delineation of measurement goals for Cfree, whether laboratory-based “ex situ” and/or field-based “in situ” application is desired, and ultimately which PSM is best-suited to fulfill the measurement objectives. Guidelines for proper calibration and validation of PSMs, including use of provisional values for polymer–water partition coefficients, determination of equilibrium status, and confirmation of nondepletive measurement conditions are defined. A hypothetical example is described to illustrate how the measurement of Cfree afforded by PSMs reduces uncertainty in assessing narcotic toxicity for sediments contaminated with polycyclic aromatic hydrocarbons. The article concludes with a discussion of future research that will improve the quality and robustness of Cfree measurements using PSMs, providing a sound scientific basis to support risk assessment and contaminated sediment management decisions. Integr Environ Assess Manag 2014;10:210–223. © 2014 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of SETAC.

Trailer length estimation in hitch angle applications

Abstract: A vehicle system for estimating a trailer length is disclosed and includes a first sensor for measuring a wheel steer angle and a second sensor for measuring a hitch angle. A processor is in communication with the first and second sensors and is operable to determine a wheel steer angle change and a hitch angle change. The processor performs a first computation if the wheel steer angle change and the hitch angle change satisfy a threshold requirement and performs a second computation if at least one of the wheel steer angle change and the hitch angle change does not satisfy the threshold requirement.

Take a Closer Look: Biofuels Can Support Environmental, Economic and Social Goals

Abstract: The US Congress passed the Renewable Fuels Standard (RFS) seven years ago. Since then, biofuels have gone from darling to scapegoat for many environmentalists, policy makers, and the general public. The reasons for this shift are complex and include concerns about environmental degradation, uncertainties about impact on food security, new access to fossil fuels, and overly optimistic timetables. As a result, many people have written off biofuels. However, numerous studies indicate that biofuels, if managed sustainably, can help solve pressing environmental, social and economic problems (Figure 1). The scientific and policy communities should take a closer look by reviewing the key assumptions underlying opposition to biofuels and carefully consider the probable alternatives. Liquid fuels based on fossil raw materials are likely to come at increasing environmental cost. Sustainable futures require energy conservation, increased efficiency, and alternatives to fossil fuels, including biofuels.

Secondary organic aerosol production from diesel vehicle exhaust: impact of aftertreatment, fuel chemistry and driving cycle

Abstract: . Environmental chamber ("smog chamber") experiments were conducted to investigate secondary organic aerosol (SOA) production from dilute emissions from two medium-duty diesel vehicles (MDDVs) and three heavy-duty diesel vehicles (HDDVs) under urban-like conditions. Some of the vehicles were equipped with emission control aftertreatment devices, including diesel particulate filters (DPFs), selective catalytic reduction (SCR) and diesel oxidation catalysts (DOCs). Experiments were also performed with different fuels (100% biodiesel and low-, medium- or high-aromatic ultralow sulfur diesel) and driving cycles (Unified Cycle,~Urban Dynamometer Driving Schedule, and creep + idle). During normal operation, vehicles with a catalyzed DPF emitted very little primary particulate matter (PM). Furthermore, photooxidation of dilute emissions from these vehicles produced essentially no SOA (below detection limit). However, significant primary PM emissions and SOA production were measured during active DPF regeneration experiments. Nevertheless, under reasonable assumptions about DPF regeneration frequency, the contribution of regeneration emissions to the total vehicle emissions is negligible, reducing PM trapping efficiency by less than 2%. Therefore, catalyzed DPFs appear to be very effective in reducing both primary PM emissions and SOA production from diesel vehicles. For both MDDVs and HDDVs without aftertreatment substantial SOA formed in the smog chamber – with the emissions from some vehicles generating twice as much SOA as primary organic aerosol after 3 h of oxidation at typical urban VOC / NOx ratios (3 : 1). Comprehensive organic gas speciation was performed on these emissions, but less than half of the measured SOA could be explained by traditional (speciated) SOA precursors. The remainder presumably originates from the large fraction (~30%) of the nonmethane organic gas emissions that could not be speciated using traditional one-dimensional gas chromatography. The unspeciated organics – likely comprising less volatile species such as intermediate volatility organic compounds – appear to be important SOA precursors; we estimate that the effective SOA yield (defined as the ratio of SOA mass to reacted precursor mass) was 9 ± 6% if both speciated SOA precursors and unspeciated organics are included in the analysis. SOA production from creep + idle operation was 3–4 times larger than SOA production from the same vehicle operated over the Urban Dynamometer Driving Schedule (UDDS). Fuel properties had little or no effect on primary PM emissions or SOA formation.

Object avoidance for a trailer backup assist system

Abstract: A trailer backup assist system, according to one embodiment, includes a steering input device for inputting a desired backing path of a trailer. The trailer backup assist system also includes a first sensor that senses a hitch angle between a vehicle and the trailer. Further, the trailer backup assist system includes a second sensor that senses a proximity of an object in a perimeter field of at least one of the vehicle and the trailer. A controller of the trailer backup assist system generates an available set of backing paths for the trailer based on the proximity of the object and the hitch angle. The available set of backing paths does not include backing paths that cross a space occupied by the object or that cause a jackknife condition between the vehicle and the trailer.

Impact of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump on prognostically important clinical outcomes in patients undergoing high-risk percutaneous coronary intervention (from the PROTECT II randomized trial)

Abstract: A periprocedural myocardial infarction, defined as the advent of new Q-waves or a creatine kinase-MB elevation >8× normal has been previously validated as predictive of subsequent mortality. We examined the effects of using this clinically relevant definition of periprocedural myocardial infarction instead of the original protocol definition on outcomes in the recent PROTECT II [A Prospective, Multi-center, Randomized Controlled Trial of the IMPELLA RECOVER LP 2.5 System Versus Intra Aortic Balloon Pump (IABP) in Patients Undergoing Non Emergent High Risk PCI] trial. In this trial, patients who were undergoing high-risk percutaneous coronary intervention (PCI) were randomized to either an intra-aortic balloon pump (IABP, n = 211) or a left ventricular assist device (Impella, n = 216). All eligible patients per study protocol were included in the analysis. Patient outcomes were compared up to 90 days, the longest available follow-up, on the composite end points of major adverse events (MAE) and major adverse cardiac and cerebral events (MACCE = death, stroke, myocardial infarction, and repeat revascularization). At 90 days, the rates of both composite end points were lower in the Impella group compared with the IABP group (MAE, 37% vs 49%, p = 0.014 respectively; MACCE, 22% vs 31%, p = 0.034 respectively). There were no differences in death or large myocardial infarction between the 2 arms. By multivariable analysis, treatment with Impella as opposed to IABP was an independent predictor for freedom from MAE (odds ratio = 0.75 [95% confidence interval 0.61 to 0.92], p = 0.007) and MACCE (odds ratio = 0.76 [95% confidence interval 0.61 to 0.96], p = 0.020) at 90 days postprocedure. In conclusion, hemodynamic support with Impella compared with IABP during high-risk PCI in the PROTECT-II trial resulted in improved event-free survival at 3-month follow-up; this finding was further supported by multivariate analyses.

System and method of calibrating a trailer backup assist system

Abstract: A system and a method are provided for calibrating a backup assist system for a trailer attached to a vehicle. The method includes driving the vehicle forward substantially straight above a threshold speed, sensing a yaw rate of the vehicle, and sensing a measured hitch angle of the trailer. A yaw sensor continuously senses the yaw rate of the vehicle and a hitch sensor continuously measures the hitch angle for determining an angle rate based on the measured hitch angle. Further, a controller determines an offset between the measured hitch angle and an actual hitch angle when the yaw rate and angle rate are substantially zero or otherwise the same.

Trajectory planner for a trailer backup assist system

Abstract: In one embodiment of the disclosed subject matter, a trailer backup assist system includes a state estimator that determines a current position of a trailer relative to a waypoint position. In addition, the trailer backup assist system includes a trajectory planner that generates first and second circular trajectories tangent to one another spanning between the current and waypoint positions. The trailer backup assist system also includes a controller that reverses the trailer to the waypoint position along the first and second circular trajectories, which are dynamically regenerated as the trailer reverses along the first circular trajectory.

Methods and systems for configuring of a trailer maneuvering system

Abstract: A system for configuring a trailer model for a trailer maneuvering system is disclosed. The system comprises a controller having a memory and being operable to communicate with the trailer maneuvering system. The controller is configured to receive trailer dimensional data from a mobile device. The trailer dimensional data may then be stored in the memory as a first trailer profile. The controller is operable to access the trailer dimensional data in the first trailer profile to determine at least one vehicle operation configured to maneuver the trailer.

System and method for calculating a horizontal camera to target distance

Abstract: A system and method for calculating a horizontal camera to target distance is provided. A camera on board a vehicle is configured to image a target on a trailer that is aligned with the vehicle. A controller is in communication with the camera and is supplied a user-obtained measurement. The controller is configured to calculate a first horizontal distance and a second horizontal distance, and to sum the first and second horizontal distances to calculate a horizontal camera to target distance.