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Showing papers by "Roma Tre University published in 2003"


Journal ArticleDOI
TL;DR: In this paper, the status of the evaluation of the MSSM Higgs sector is reviewed and the phenomenological impact of recently obtained corrections is discussed, and it is shown that the upper bound on mh within the MssM is shifted upwards.
Abstract: The status of the evaluation of the MSSM Higgs sector is reviewed. The phenomenological impact of recently obtained corrections is discussed. In particular it is shown that the upper bound on mh within the MSSM is shifted upwards. Consequently, lower limits on \(\tan\beta\) obtained by confronting the upper bound as function of \(\tan\beta\) with the lower bound on mh from Higgs searches are significantly weakened. Furthermore, th e region in the MA-\(\tan\beta\)-plane where the coupling of the lightest Higgs boson to down-type fermions is suppressed is modified. The presently not calculated higher-order corrections to the Higgs-boson mass matrix are estimated to shift the mass of the lightest Higgs boson by up to 3 GeV.

955 citations


Journal ArticleDOI
TL;DR: The neuroglobin structure suggests that the classical globin fold is endowed with striking adaptability, indicating that hemoglobin and myoglobin are just two examples within a wide and functionally diversified protein homology superfamily.

287 citations


Journal ArticleDOI
TL;DR: In this paper, the authors studied the nucleation and growth of cataclastic fault cores from fractured damage zones in extensional and strike-slip fault zones in carbonate rocks.

283 citations


Journal ArticleDOI
TL;DR: The results of a research project aimed at implementing a 'realistic' 3D Embodied Agent that can be animated in real-time and is 'believable and expressive': that is, able to coherently communicate complex information through the combination and the tight synchronisation of verbal and nonverbal signals.
Abstract: This paper describes the results of a research project aimed at implementing a 'realistic' 3D Embodied Agent that can be animated in real-time and is 'believable and expressive': that is, able to coherently communicate complex information through the combination and the tight synchronisation of verbal and nonverbal signals. We describe, in particular, how we 'animate' this Agent (that we called Greta) so as to enable her to manifest the affective states that are dynamically activated and de-activated in her mind during the dialog with the user. The system is made up of three tightly interrelated components: • A representation of the Agent Mind: this includes long and short-term affective components (personality and emotions) and simulates how emotions are triggered and decay over time according to the Agent's personality and to the context, and how several emotions may overlap. Dynamic belief networks with weighting of goals is the formalism we employ to this purpose. • A mark-up language to denote the communicative meanings that may be associated with dialog moves performed by the Agent. • A translation of the Agent's tagged move into a face expression, that combines appropriately the available channels (gaze direction, eyebrow shape, head direction and movement etc). The final output is a 3-D facial model that respects the MPEG-4 standard and uses MPEG- 4 Facial Animation Parameters to produce facial expressions. Throughout the paper, we illustrate the results obtained, with an example of dialog in the domain of 'Advice about eating disorders'. The paper concludes with an analysis of advantages of our cognitive model of emotion triggering and of the problems found in testing it. Although we did not yet complete a formal evaluation of our system, we briefly describe how we plan to assess the agent's believability in terms of consistency of its communicative behaviour.

280 citations


Journal ArticleDOI
TL;DR: In this article, a photometric and spectroscopic identification of 122 hard X-ray sources recently discov- ered by XMM-Newton in the 2-10 keV band (the HELLAS2XMM 1dF sample) is presented.
Abstract: We present results from the photometric and spectroscopic identification of 122 X-ray sources recently discov- ered by XMM-Newton in the 2-10 keV band (the HELLAS2XMM 1dF sample). Their flux cover the range 8 10 15 4 10 13 erg cm 2 s 1 and the total area surveyed is 0.9 square degrees. One of the most interesting results (which is found also in deeper sourveys) is that about 20% of the hard X-ray selected sources have an X-ray to optical flux ratio (X/O) ten times or more higher than that of optically selected AGN. Unlike the faint sources found in the ultra-deep Chandra and XMM-Newton surveys, which reach X-ray (and optical) fluxes more than one order of magnitude lower than the HELLAS2XMM survey sources, many of the extreme X/O sources in our sample have R 10 (to be compared with 9 sources known from the deeper, pencil-beam surveys). Eight of them are narrow line QSO (seemingly the extension to very high luminosity of the type 2 Seyfert galax- ies), four are broad line QSO. The results from our survey are also used to make reliable predictions about the luminosity of the sources not yet spectroscopically identified, both in our sample and in deeper Chandra and XMM-Newton samples. We then use a combined sample of 317 hard X-ray selected sources (HELLAS2XMM 1dF, Chandra Deep Field North 1Msec, Chandra SSA13 and XMM-Newton Lockman Hole flux limited samples), 221 with measured redshifts, to evaluate the cosmo- logical evolution of the hard X-ray source's number and luminosity densities. Looking backward in time, the low luminosity sources (log L2 10 keV = 43 44 erg s 1 ) increase in number at a much slower rate than the very high luminosity sources (log L2 10 keV> 44: 5e rg s 1 ), reaching a maximum around z= 1 and then levelling o beyond z= 2. This translates into an accretion driven luminosity density which is dominated by sources with log L2 10 keV 44: 5e rg s 1 appear, with yet rather large uncertainties, to be comparable between z= 2 and 4.

264 citations


Journal ArticleDOI
TL;DR: In this paper, a laboratory analogue of a three-layer linear viscous slab upper mantle-lower mantle system is established in a silicone putty, honey and crystallized honey tank experiment.
Abstract: [1] A laboratory analogue of a three-layer linear viscous slab-upper mantle-lower mantle system is established in a silicone putty, honey and crystallized honey tank experiment. The same setup as in the numerical investigation (part 1) is used. We focus on the interaction of the slab with the induced passive mantle flow by widely varying the mantle volume flux boundary conditions. In our numerical experiments the lateral volume flux was set to zero. In interpreting the results relative to the real Earth, the base of the box is taken as the bottom of the mantle convection system, while the lateral boundaries may be associated with the presence of other nearby slabs. Dynamic force equilibrium, assessed on the basis of an analytical review of forces, is described for four different phases: (1) the subduction initiation instability, (2) the accelerating dynamic free fall phase of the slab, (3) the dynamic interaction with the 660-km discontinuity, and (4) a final phase of steady state trench retreat. Phase 3 is an important feature not observed in the numerical experiments. This highly dynamic phase of interrupted trench retreat can therefore be attributed to boundary conditions on mantle volume flux. On the basis of integration constants of force equilibrium in phases 2 and 4 we identify two different classes of volume flux: one in which the lateral boundary can be considered open and the other class where it is “closed.” Closed boundary condition cases are obtained if any of the lateral box boundaries are 600 km away from the slab. Assuming a one-to-one relation between trench retreat and back arc spreading, enigmatic observations of episodic opening of back arc basins can be explained by our experimental observations.

252 citations


Journal ArticleDOI
C. Adloff, V. Andreev, B. Andrieu, T. Anthonis1  +296 moreInstitutions (26)
TL;DR: In this paper, the e(+)p single and double differential cross sections for neutral and charged current processes were measured with the H1 detector at HERA and the cross sections were taken in 1999 and 2000 at a centre-of-mass energy of roots = 319 GeV and correspond to an integrated luminosity of 65.2 pb(-1).
Abstract: The inclusive e(+)p single and double differential cross sections for neutral and charged current processes axe measured with the H1 detector at HERA. The data were taken in 1999 and 2000 at a centre-of-mass energy of roots = 319 GeV and correspond to an integrated luminosity of 65.2 pb(-1). The cross sections are measured in the range of four-momentum transfer squared Q(2) between 100 and 30 000 GeV2 and Bjorken x between 0.0013 and 0.65. The neutral current analysis for the new e(+)p data and the earlier e-p data taken in 1998 and 1999 is extended to small energies of the scattered electron and therefore to higher values of inelasticity y, allowing a determination of the longitudinal structure function F-L at high Q(2) (110 - 700 GeV2). A new measurement of the structure function x (F) over tilde (3) is obtained using the new e(+)p and previously published e p neutral current cross section data at high Q(2). These data together with H1 low Q(2) precision data are further used to perform new next-to-leading order QCD analyses in the framework of the Standard Model to extract flavour separated parton distributions in the proton.

223 citations


Journal ArticleDOI
TL;DR: In this paper, a small sample of type 2 Seyfert galaxies whose X-ray spectra changed appearance on time-scales of years, becoming reflection-dominated from Compton-thin, or vice versa.
Abstract: We discuss the properties of a small sample of type 2 Seyfert galaxies whose X-ray spectra changed appearance on time-scales of years, becoming reflection-dominated from Compton-thin, or vice versa. A reflection-dominated spectrum is usually taken as evidence of Compton-thick absorption, but we instead argue that such a spectrum is due to a temporary switching-off of the nuclear radiation. The observations discussed here may help to explain mismatches between optical and X-ray classifications, and provide new strong and direct evidence for the presence of more than one cold circumnuclear region in type 2 Seyfert galaxies.

217 citations


Journal ArticleDOI
TL;DR: In this paper, the authors complete the effective potential calculation of the two-loop, top/bottom Yukawa corrections to the Higgs boson masses in the minimal supersymmetric standard model, by computing the O(α t 2 +α t α b +α b 2 ) contributions for arbitrary values of the bottom Yukawa coupling.

210 citations


Journal ArticleDOI
TL;DR: The suppression of the NO-mediated cell death in plants overexpressing AtCYS1 provides the evidence that NO is not cytotoxic for the plant, indicating that NO functions as cell death trigger through the stimulation of an active process, in which cysteine proteases and theirs proteinaceous inhibitors appear to play a crucial role.
Abstract: In plants, cysteine protease inhibitors are involved in the regulation of protein turnover and play an important role in resistance against insects and pathogens. AtCYS1 from Arabidopsis thaliana encodes a protein of 102 amino acids that contains the conserved motif of cysteine protease inhibitors belonging to the cystatin superfamily (GlnVal-Val-Ala-Gly). Recombinant A. thaliana cystatin-1 (AtCYS1) was expressed in Escherichia coli and purified. AtCYS1 inhibits the catalytic activity of papain (Kd ¼ 4.0 · 10 )2 lM ,a t pH 7.0 and 25� C), generally taken as a molecular model of cysteine proteases. The molecular bases for papain inhibition by AtCYS1 have been analysed taking into account the three-dimensional structure of the papain–stefin B complex. AtCYS1 is constitutively expressed in roots and in developing siliques of A. thaliana. In leaves, AtCYS1 is strongly induced by wounding, by challenge with avirulent pathogens and by nitric oxide (NO). The overexpression of AtCYS1 blocks cell death activated by either avirulent pathogens or by oxidative and nitrosative stress in both A. thaliana suspension cultured cells and in transgenic tobacco plants. The suppression of the NO-mediated cell death in plants overexpressing AtCYS1 provides the evidence that NO is not cytotoxic for the plant, indicating that NO functions as cell death trigger through the stimulation of an active process, in which cysteine proteases and theirs proteinaceous inhibitors appear to play a crucial role.

209 citations


Journal ArticleDOI
P. Astier1, D. Autiero2, A. Baldisseri, M. Baldo-Ceolin3  +169 moreInstitutions (23)
TL;DR: In this paper, the results of a search for vμ → v e oscillations in the NOMAD experiment at CERN were presented and the 90% confidence limits obtained are Δm2 < 0.4 eV 2 for maximal mixing and sin2(2θ) < 1.4 × 10-3 for large Δm 2.

Journal ArticleDOI
TL;DR: In this article, the role of the gravitational force exerted by a subducting slab on the deformation of the subducted plate itself was investigated using 3D scaled lithospheric experiments, and it was shown that intraplate stresses and strain localization are favored by the presence of a weakness zone, such as the one generated by the Afar plume.

Journal ArticleDOI
TL;DR: In this article, it was shown that cataclastic fabric with fractal dimensions D V2.7 is preferred for slip localisation in narrow shear bands in carbonate faults.

Journal ArticleDOI
TL;DR: The structural, inhibition, and bio-medical aspects of BPTI are reported, which include inhibition of nitric oxide synthase type-I and -II action and impairs K+ transport by Ca2+-activated K+ channels.
Abstract: The pancreatic Kunitz inhibitor, also known as aprotinin, bovine basic pancreatic trypsin inhibitor (BPTI), and trypsin-kallikrein inhibitor, is one of the most extensively studied globular proteins. It has proved to be a particularly attractive and powerful tool for studying protein conformation as well as molecular bases of protein/protein interaction(s) and (macro)molecular recognition. BPTI has a relatively broad specificity, inhibiting trypsin- as well as chymotrypsin- and elastase-like serine (pro)enzymes endowed with very different primary specificity. BPTI reacts rapidly with serine proteases to form stable complexes, but the enzyme: inhibitor complex formation may involve several intermediates corresponding to discrete reaction steps. Moreover, BPTI inhibits the nitric oxide synthase type-I and -II action and impairs K+ transport by Ca2+-activated K+ channels. Clinically, the use of BPTI in selected surgical interventions, such as cardiopulmonary surgery and orthotopic liver transplantation, is advised, as it significantly reduces hemorrhagic complications and thus blood-transfusion requirements. Here, the structural, inhibition, and bio-medical aspects of BPTI are reported.

Journal ArticleDOI
TL;DR: In this paper, 13 papers from an international field of contributors have studied the intraplate strike-slip deformation belts from Africa, Antarctica, Eurasia, North America and South America.
Abstract: Intraplate strike-slip deformation belts are common tectonic features, particularly at convergent plate boundaries, where they are produced by both oblique convergence and continental indentation. These lithosphere-scale structures, which also occur in other geodynamic environments such as passive margins, are characterized by complex structural architectures, by the occurrence of large earthquakes, and by the fast uplift and/or subsidence of localized crustal sectors. Intraplate strike-slip belts can also control the ascent and emplacement of deeply sourced magmas. In some cases, intraplate strike-slip belts link with oceanic fracture zones and transform faults, transferring transform shear from the ridges to the interior of the plates. This evidence has an important impact of the classical concept of transform faulting. This volume contains 13 papers from an international field of contributors. Studies of intraplate strike-slip deformation belts from Africa, Antarctica, Eurasia, North America and South America are included.

Journal ArticleDOI
TL;DR: In this paper, Cimatti et al. reported the discovery of large-scale structures of X-ray sources in the 1Ms observation of the Chandra Deep Field South (CDFS).
Abstract: We report the discovery of large-scale structures of X-ray sources in the 1 Ms observation of the Chandra Deep Field South. Two main structures appear as narrow (?z 0.02) spikes in the source redshift distribution at z = 0.67 and 0.73, respectively. Their angular distribution spans a region at least ~17' wide, corresponding to a physical size of 7.3 h Mpc at a redshift of z ~ 0.7 (?m = 0.3, ?? = 0.7). These spikes are populated by 19 sources each, which are mainly identified as active galactic nuclei (AGNs). Two sources in each spike are extended in X-rays, corresponding to galaxy groups/clusters embedded in larger structures. The X-ray source redshift distribution shows other spikes, the most remarkable at z = 1.04, 1.62, and 2.57. This is one of the first evidences for large-scale structure traced by X-ray sources and for spatial clustering of X-ray-selected AGNs. The X-ray data have been complemented with the spectroscopic data from the K20 near-infrared survey (Cimatti et al.), which covers ~1/10 of the X-ray field. In this survey, too, the source redshift distribution shows several spikes. Two narrow structures at z = 0.67 and 0.73 (again with ?z ~ 0.02) are the most significant features, containing 24 and 47 galaxies, respectively. While the K20 structure at z = 0.73 is dominated by a standard galaxy cluster with a significant concentration around a central cD galaxy and morphological segregation, the galaxies at z = 0.67 constitute a loose structure rather uniformly distributed along the K20 field. Moreover, we find a very good correlation (almost one-to-one) between less prominent peaks detected in the redshift distributions of X-ray and K20 sources. In particular, at z < 1.3 we find that five out of the six more significant K20 peaks have a corresponding peak in the X-ray-selected sources and, similarly, all five X-ray peaks below that redshift have a corresponding K20 peak. Since the K20 survey sensitivity drops beyond z ~ 1.3, structures at higher redshift are traced only by the X-ray sources. This correlation suggests that AGNs (from the X-ray data) and (early-type) galaxies (from the K20 survey) are tracing the same underlying structures. We also compared the X-ray and K-band catalogs to search for enhanced X-ray activity in the sources in the two main redshift spikes. While in the structure at z = 0.73 the fraction of X-ray sources is the same as in the field, in the structure at z = 0.67 it is higher by a factor of ~2, suggesting that X-ray activity may be triggered preferentially in the structure at z = 0.67. Given the limited statistics, this result is significant only at the ~2 ? level.

Journal ArticleDOI
TL;DR: It is found that nonparaxiality couples the Cartesian components of the field and that the resultant longitudinal component is greater than the correction to the transverse component orthogonal to the optical axis.
Abstract: We describe monochromatic light propagation in uniaxial crystals by means of an exact solution of Maxwell’s equations. We subsequently develop a paraxial scheme for describing a beam traveling orthogonal to the optical axis. We show that the Cartesian field components parallel and orthogonal to the optical axis are extraordinary and ordinary, respectively, and hence uncoupled. The ordinary component exhibits a standard Fresnel behavior, whereas the extraordinary one exhibits interesting anisotropic diffraction dynamics. We interpret the anisotropic diffraction as a composition of two spatial geometrical affinities and a single Fresnel propagation step. As an application, we obtain the analytical expression of the extraordinary Gaussian beam. We then derive the first nonparaxial correction to the paraxial beam, thus giving a scheme for describing slightly nonparaxial fields. We find that nonparaxiality couples the Cartesian components of the field and that the resultant longitudinal component is greater than the correction to the transverse component orthogonal to the optical axis. Finally, we derive the analytical expression for the nonparaxial correction to the paraxial Gaussian beam.

Journal ArticleDOI
TL;DR: In this paper, the presence or absence of hidden broad-line regions (HBLRs) in Seyfert 2 galaxies is regulated by the rate at which matter accretes onto a central supermassive black hole, in units of the Eddington rate.
Abstract: In this Letter, we present evidence suggesting that the absence or presence of hidden broad-line regions (HBLRs) in Seyfert 2 galaxies is regulated by the rate at which matter accretes onto a central supermassive black hole, in units of the Eddington rate. Evidence is based on data from a subsample of type 2 active galactic nuclei extracted from the Tran spectropolarimetric sample and made up of all those sources that also have good-quality X-ray spectra available and for which a bulge luminosity can be estimated. We use the intrinsic (i.e., unabsorbed) X-ray luminosities of these sources and their black hole masses (estimated by using the well-known relationship between nuclear mass and bulge luminosity in galaxies) to derive the nuclear accretion rate in Eddington units. We find that virtually all HBLR sources have accretion rates larger than a threshold value of thres 10-3 (in Eddington units), while non-HBLR sources lie at thres. These data nicely fit predictions from a model proposed by Nicastro in which the broad-line regions (BLRs) are formed by accretion disk instabilities occurring in proximity of the critical radius at which the disk changes from gas pressure dominated to radiation pressure dominated. This radius diminishes with decreasing ; for low enough accretion rates (and therefore luminosities), the critical radius becomes smaller than the innermost stable orbit and BLRs cannot form.

Journal ArticleDOI
TL;DR: In this article, the presence or absence of Hidden Broad Line Regions (HBLRs) in Seyfert 2 galaxies is regulated by the rate at which matter accretes onto a central supermassive black hole, in units of Eddington rate.
Abstract: In this paper we present evidence suggesting that the absence or presence of Hidden Broad Line Regions (HBLRs) in Seyfert 2 galaxies is regulated by the rate at which matter accretes onto a central supermassive black hole, in units of Eddington rate. We use the intrinsic (i.e. unabsorbed) X-ray luminosities of these sources and their black hole masses (estimated by using the well known relationship between nuclear mass and bulge luminosity in galaxies) to derive the nuclear accretion rate in units of Eddington. We find that virtually all HBLR sources have accretion rate larger than a threshold value of $\dot{m}_{thres} \simeq 10^{-3}$ (in Eddington units), while non-HBLR sources lie at $\dot{m} \ls \dot{m}_{thres}$. These data nicely fit predictions from a model proposed by Nicastro (2000), in which the Broad Line Regions (BLRs) are formed by accretion disk instabilities occurring in proximity of the critical radius at which the disk changes from gas pressure dominated to radiation pressure dominated. This radius diminishes with decreasing accretion rates; for low enough accretion rates (and therefore luminosities), the critical radius becomes smaller than the innermost stable orbit, and BLRs cannot form.

Journal ArticleDOI
TL;DR: Interestingly, it is found that the Nef-dependent release of inflammatory factors correlated with the activation of the NF-κB transcription factor, mainly in its p50/p50 homodimeric form, and in a de novo protein synthesis-independent manner.
Abstract: It has been recently reported that the endogenous expression of HIV-1 Nef in human monocyte/macrophages induces the release of chemokines and other as yet unidentified soluble factors leading to multiple effects of pathogenic significance, such as the recruitment and activation of quiescent lymphocytes. However, the description of underlying molecular mechanisms remained elusive. We recently demonstrated that human monocyte-derived macrophages (MDM) efficiently internalize soluble rNef, thereby inducing effects largely resembling those observed in cells endogenously expressing Nef. By exploiting the rNef/MDM model, we sought to gain more insights on the molecular mechanisms underlying the response of MDM to Nef. Array analysis for the detection of transcripts from a large number of monokines, chemokines, cytokines, and receptors thereof showed that MDM promptly responded to rNef treatment by increasing the transcription of genes for several inflammatory factors. Analysis of supernatants revealed that rNef treatment induced the release of macrophage inflammatory proteins 1alpha and 1beta, IL-1beta, IL-6, and TNF-alpha. Conversely, rNefs mutated in domains critical for the interaction with the endocytotic machinery (i.e., EE155-156QQ, and DD174-175AA) were ineffective. Interestingly, we found that the Nef-dependent release of inflammatory factors correlated with the activation of the NF-kappaB transcription factor, mainly in its p50/p50 homodimeric form, and in a de novo protein synthesis-independent manner. Our data add new hints supporting the idea that the presence of Nef is per se heavily detrimental for monocyte/macrophages and relative cross-talking cell types.

Journal ArticleDOI
TL;DR: In this paper, Anderson, D. D., Papick, I. J., and Fontana, M., Loper, K. A. (2001a) extended the notion of star operation and generalized Kang's notion of a star Nagata r...
Abstract: In 1994, Matsuda and Okabe introduced the notion of semistar operation. This concept extends the classical concept of star operation (cf. for instance, Gilmer's book (Gilmer, R. (1972). Multiplicative Ideal Theory. New York: Marcel Dekker) and, hence, the related classical theory of ideal systems based on the works by W. Krull, E. Noether, H. Prufer and P. Lorenzen from 1930's. Fontana and Loper investigated properties of the Kronecker function rings which arise from arbitrary semistar operations on an integral domain D (Fontana M., Loper K. A. (2001a). Kronecker function rings: a general approach. In Anderson, D. D., Papick, I. J., eds. Ideal Theoretic Methods in Commutative Algebra. Lecture Notes Pure Appl. Math. 220, Marcel Dekker, pp. 189–205 and Fontana, M., Loper, K. A. (2001b). A Krull-type theorem for the semistar integral closure of an integral domain. ASJE Theme Issue “Commutative Algebra” 26:89–95). In this paper we extend that study and also generalize Kang's notion of a star Nagata r...

Journal ArticleDOI
TL;DR: It is shown that any partially polarized, partially coherent source can be expressed in terms of a suitable superposition of transverse coherent modes with orthogonal polarization states.
Abstract: It is shown that any partially polarized, partially coherent source can be expressed in terms of a suitable superposition of transverse coherent modes with orthogonal polarization states. Such modes are determined through the solution of a system of two coupled integral equations. An example, for which the modal decomposition is obtained in closed form in terms of fully linearly polarized Hermite Gaussian modes, is given.

Journal ArticleDOI
K. Sh Egiyan, N. Dashyan, Misak Sargsian1, S. Stepanyan2  +229 moreInstitutions (33)
TL;DR: In this article, the authors measured the ratio of electron scattering cross sections for all nuclei and showed that the momentum distributions at high-momenta have the same shape for different nuclei, and differ only by a scale factor.
Abstract: The ratios of inclusive electron scattering cross sections of ${}^{4}\mathrm{He},$ ${}^{12}\mathrm{C},$ and ${}^{56}\mathrm{Fe}$ to ${}^{3}\mathrm{He}$ have been measured for the first time. It is shown that these ratios are independent of ${x}_{B}$ at ${Q}^{2}g1.4{\mathrm{GeV}}^{2}$ for ${x}_{B}g1.5,$ where the inclusive cross section depends primarily on the high momentum components of the nuclear wave function. The observed scaling shows that the momentum distributions at high-momenta have the same shape for all nuclei and differ only by a scale factor. The observed onset of the scaling at ${Q}^{2}g1.4{\mathrm{GeV}}^{2}$ and ${x}_{B}g1.5$ is consistent with the kinematical expectation that two-nucleon short range correlations (SRC) dominate the nuclear wave function at ${p}_{m}\ensuremath{\gtrsim}300\mathrm{MeV}/c.$ The values of these ratios in the scaling region can be related to the relative probabilities of SRC in nuclei with $Ag~3.$ Our data, combined with calculations and other measurements of the ${}^{3}\mathrm{H}\mathrm{e}/\mathrm{d}\mathrm{e}\mathrm{u}\mathrm{t}\mathrm{e}\mathrm{r}\mathrm{i}\mathrm{u}\mathrm{m}$ ratio, demonstrate that for nuclei with $Ag~12$ these probabilities are 4.9--5.9 times larger than in deuterium, while for ${}^{4}\mathrm{He}$ it is larger by a factor of about 3.8.

Journal ArticleDOI
TL;DR: In this article, Cimatti et al. reported the discovery of large scale structures of X-ray sources in the 1Msec observation of the Chandra Deep Field South (CDFS).
Abstract: We report the discovery of large scale structures of X-ray sources in the 1Msec observation of the Chandra Deep Field South. Two main structures appear as narrow (Delta_z < 0.02) spikes in the source redshift distribution at z=0.67 and z=0.73, respectively. Their angular distribution spans a region at least ~ 17 arcmin wide, corresponding to a physical size of 7.3 h_{70}^{-1} Mpc at a redshift of z ~ 0.7 (Omega_m=0.3, Omega_{Lambda}=0.7). These spikes are populated by 19 sources each, which are mainly identified as Active Galactic Nuclei (AGN). Two sources in each spike are extended in X-rays, corresponding to galaxy groups/clusters embedded in larger structures. The X-ray source redshift distribution shows other spikes, the most remarkable at z=1.04, 1.62 and 2.57. This is one of the first evidences for large scale structure traced by X-ray sources and for spatial clustering of X-ray selected AGN. The X-ray data have been complemented with the spectroscopic data from the K20 near infrared survey (Cimatti et al. 2002), which covers ~1/10 of the X-ray field. Also in this survey the source redshift distribution shows several spikes. Two narrow structures at z=0.67 and z=0.73 (again with Delta_z ~ 0.02) are the most significant features, containing 24 and 47 galaxies, respectively. While the K20 structure at z=0.73 is dominated by a standard galaxy cluster with a significant concentration around a central cD galaxy and morphological segregation, the galaxies at z=0.67 constitute a loose structure rather uniformly distributed along the K20 field.[abridged]

Journal ArticleDOI
TL;DR: The results showed that the PI3K pathway, as well as ER, were strongly involved in both G1-S progression and cyclin D1 promoter activity by acting on its proximal region (-254 base pairs), indicating that in HepG2 cells, different rapid/nongenomic estradiol-induced signal transduction pathways modulate the multiple steps of G 1-S phase transition.
Abstract: We reported previously in HepG2 cells that estradiol induces cell cycle progression throughout the G1–S transition by the parallel stimulation of both PKC- and ERK signaling molecules. The analysis of the cyclin D1 gene expression showed that only the MAP kinase pathway was involved. Here, the presence of rapid/nongenomic, estradiol-regulated, PI3K/AKT signal transduction pathway, its modulation by the levels of the tumor suppressor PTEN, its cross-talk with the ERK pathway, and its involvement in DNA synthesis and cyclin D1 gene promoter activity have all been studied in HepG2 cells. 17-Estradiol induced the rapid and biphasic phosphorylation of AKT. These phosphorylations were independent of each other, being the first wave of activation independent of the estrogen receptor (ER), whereas the second was dependent on ER. Both activations were dependent on PI3K activity; furthermore, the ERK pathway modulated AKT phosphorylation by acting on the PTEN levels. The results showed that the PI3K pathway, as well as ER, were strongly involved in both G1–S progression and cyclin D1 promoter activity by acting on its proximal region (254 base pairs). These data indicate that in HepG2 cells, different rapid/nongenomic estradiol-induced signal transduction pathways modulate the multiple steps of G1–S phase transition.

Journal ArticleDOI
TL;DR: The results suggest that both light and auxin finely tune PAO expression during the light-induced differentiation of the cell wall in the maize mesocotyl epidermal tissues.
Abstract: Exogenously supplied auxin (1-naphthaleneacetic acid) inhibited light-induced activity increase of polyamine oxidase (PAO), a hydrogen peroxide-producing enzyme, in the outer tissues of maize ( Zea mays ) mesocotyl. The same phenomenon operates at PAO protein and mRNA accumulation levels. The wall-bound to extractable PAO activity ratio was unaffected by auxin treatment, either in the dark or after light exposure. Ethylene treatment did not affect PAO activity, thus excluding an effect of auxin via increased ethylene biosynthesis. The auxin polar transport inhibitors N 1 -naphthylphthalamic acid or 2,3,5-triiodobenzoic acid caused a further increase of PAO expression in outer tissues after light treatment. The small increase of PAO expression, normally occurring in the mesocotyl epidermis during plant development in the dark, was also inhibited by auxin, although to a lesser extent with respect to light-exposed tissue, and was stimulated by N 1 -naphthylphthalamic acid or 2,3,5-triiodobenzoic acid, thus suggesting a complex regulation of PAO expression. Immunogold ultrastructural analysis in epidermal cells revealed the association of PAO with the secretory pathway and the cell walls. The presence of the enzyme in the cell walls of this tissue greatly increased in response to light treatment. Consistent with auxin effects on light-induced PAO expression, the hormone treatment inhibited the increase in immunogold staining both intraprotoplasmically and in the cell wall. These results suggest that both light and auxin finely tune PAO expression during the light-induced differentiation of the cell wall in the maize mesocotyl epidermal tissues.

Journal ArticleDOI
TL;DR: It is shown how probabilistic expert systems can be used to structure and solve complex cases of forensic identification involving DNA traces that might be mixtures of several DNA profiles.

Journal ArticleDOI
TL;DR: It is argued that a left-hand circularly polarized incoming beam, endowed with a circular symmetric profile, gives rise, inside the crystal, to a right-handCircularly polarized vortex of order 2, which is investigated by means of a power exchange analysis.
Abstract: We deduce the expressions for the two circularly polarized components of a paraxial beam propagating along the optical axis of a uniaxial crystal. We find that each of them is the sum of two contributions, the first being a free field and the second describing the interaction with the opposite component. Moreover, we expand both components as a superposition of vortices of any order, thus obtaining a complete physical picture of the interaction dynamics. Consequently, we argue that a left-hand circularly polarized incoming beam, endowed with a circular symmetric profile, gives rise, inside the crystal, to a right-hand circularly polarized vortex of order 2. The efficiency of this vortex generation is investigated by means of a power exchange analysis. The Gaussian case is fully discussed, showing the relevant features of the vortex generation.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the effect of rotation on the evolution of double-degenerate white dwarf systems, which are possible progenitors of Type Ia supernovae.
Abstract: We investigate the effect of rotation on the evolution of double-degenerate white dwarf systems, which are possible progenitors of Type Ia supernovae. We assume that prior to merging, the two white dwarfs rotate synchronously at the orbital frequency and that in the merger process, the lighter white dwarf is transformed into a thick disk from which the more massive white dwarf initially accretes at a very high rate (~10-5 M☉ yr-1). Because of the lifting effect of rotation, the accreting white dwarf expands until the gravitational acceleration and centripetal acceleration required for binding at the surface become equal, initiating a Roche instability. The white dwarf continues to accrete matter from the disk, but at a rate that is determined by the balance between two competing processes operating in outer layers: (1) heating, expansion, and spin-up due to accretion and (2) cooling and contraction due to thermal diffusion. The balance produces an accretion rate such that the angular velocity of the white dwarf ωWD and the break-up angular velocity ωcr remain equal. Because of the deposition of angular momentum by accreted matter and the contraction of the accreting star, ωWD increases continuously until the rotational energy reaches about 14% of the gravitational binding energy; then, another instability sets in: the structure is forced to adopt an elliptical shape and emit gravitational waves. Thereafter, a balance between the rate of deposition of angular momentum by accreted matter and the rate of loss of angular momentum by gravitational waves produces a nearly constant or "plateau" accretion rate of ~4 × 10-7 M☉ yr-1. The mass of the accreting white dwarf can increase up to and beyond the Chandresekhar mass limit for nonrotating white dwarfs before carbon ignition occurs. Independent of the initial value of the accretion rate, the physical conditions suitable for carbon ignition are achieved at the center of the accreting white dwarf and, because of the high electron degeneracy, the final outcome is an event of SN Ia proportions. Our results apply to merged binary white dwarf systems which, at the onset of explosive carbon ignition, have a total mass in the range 1.4-1.5 M☉.

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TL;DR: The crystallographic structure of bioapatite in human fetuses was investigated by synchrotron radiation x-ray diffraction and microdiffraction techniques and rietveld refinement analyses of XRD and micro -XRD data allow for quantitative probing of the structural modifications of bioAPatite.