University of Los Andes

About: University of Los Andes is a education organization based out in Bogotá, Colombia. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 17616 authors who have published 25555 publications receiving 413463 citations.

Nonequilibrium transition induced by mass media in a model for social influence

Abstract: We study the effect of mass media, modeled as an applied external field, on a social system based on Axelrod's model for the dissemination of culture. The numerical simulations show that the system undergoes a nonequilibrium phase transition between an ordered phase (homogeneous culture) specified by the mass media and a disordered (culturally fragmented) one. The critical boundary separating these phases is calculated on the parameter space of the system, given by the intensity of the mass media influence and the number of options per cultural attribute. Counterintuitively, mass media can induce cultural diversity when its intensity is above some threshold value. The nature of the phase transition changes from continuous to discontinuous at some critical value of the number of options.

Paradox versus dilemma mindset: A theory of how women leaders navigate the tensions between agency and communion

Abstract: A wealth of literature documents that women leaders can face simultaneous and yet conflictual demands for both agency and communion, due to the incongruence of their leader role and gender role demands. However, we still know little about why some women cope with the tensions between agency and communion better than others and what implications are involved. Using a paradox perspective, we develop a theoretical model to explain how women leaders experience and respond to agency-communion tensions, which impacts their intrapersonal and interpersonal outcomes. Specifically, we propose that in response to experiencing tensions fueled by the dual demands for agency and communion, women leaders can adopt a paradox mindset that simultaneously embraces agency and communion, or a dilemma mindset that dichotomizes agency and communion. The paradox mindset helps women leaders build psychological resilience, identity coexistence, and leadership effectiveness, whereas those who adopt a dilemma mindset experience depleted resilience, identity separation, and lowered leadership effectiveness. Further, our model highlights individual, interpersonal, and organizational conditions that shape women's experience and stimulate a paradox mindset versus a dilemma mindset. We conclude by discussing theoretical and practical implications of our model.

Seasonality in fruit availability affects frugivorous primate biomass and species richness

Abstract: We examine the effect of total annual food abundance and seasonal availability on the biomass and species richness for frugivorous primates on three continents (n=16 sites) by data on fruit fall. We reveal that the best-fit models for predicting primate biomass include total annual fruit fall (positive), seasonality (negative) and biogeography (Old World>New World and mainland>island) and that these factors explain 56–67% of the variation. For the number of species, the best-fit models include seasonality (negative) and biogeography (Old World>New World and mainland>island) but not total annual fruit fall. Annual temperature has additional effects on primate biomass when the effects of fruits and biogeography are controlled, but there is no such effect on species richness. The present results indicate that, measured on local scales, primate biomass and number of species is affected by the seasonal variation in food availability.

Enolase: A Key Player in the Metabolism and a Probable Virulence Factor of Trypanosomatid Parasites—Perspectives for Its Use as a Therapeutic Target

Abstract: Glycolysis and glyconeogenesis play crucial roles in the ATP supply and synthesis of glycoconjugates, important for the viability and virulence, respectively, of the human-pathogenic stages of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp. These pathways are, therefore, candidate targets for antiparasite drugs. The glycolytic/gluconeogenic enzyme enolase is generally highly conserved, with similar overall fold and identical catalytic residues in all organisms. Nonetheless, potentially important differences exist between the trypanosomatid and host enzymes, with three unique, reactive residues close to the active site of the former that might be exploited for the development of new drugs. In addition, enolase is found both in the secretome and in association with the surface of Leishmania spp. where it probably functions as plasminogen receptor, playing a role in the parasite's invasiveness and virulence, a function possibly also present in the other trypanosomatids. This location and possible function of enolase offer additional perspectives for both drug discovery and vaccination.