Showing papers in "Journal of Laboratory and Clinical Medicine in 2005"

TL;DR: It is concluded that an EIA that detects anti-PF4/polyanion antibodies of only the IgG class has greater diagnostic usefulness in revealing clinical HIT than does an assay that also detects IgA and IgM class antibodies.

TL;DR: The phenotype-driven approach is taking advantage of selective breeding of animals (primarily rats) that exhibit a desired phenotype, like the useful SHR as mentioned in this paper, which allows dissection and isolation of various factors associated with regulation of blood pressure, inheritance of hypertensive traits, and cellular responses to injury.

TL;DR: Although the liver is considered the main source of CRP and a source of PCT, serum levels of these acute-phase proteins are not significantly lower in patients with cirrhosis than in other patients, and the predictive power ofCRP and PCT for infection was similar for patients with and without Cirrhosis.

TL;DR: Urinary L-FABP is more sensitive than urinary protein in predicting the progression of CKD, and is therefore a useful clinical marker in the monitoring of CKd.

TL;DR: This review comprehensively reviews the central nervous system complications that have been reported with M. pneumoniae and indicates that CNS involvement is probably the most common site of involvement in addition to the respiratory system.

TL;DR: It is speculated that PCOS, associated with obesity and extreme obesity, is a treatable promoter of IIH and is associated with reduced CSF resorption in the arachnoid villi of the brain.

TL;DR: In this paper, a 10-year follow-up study showed significant decreases in alanine aminotransferase (ALT), AST, and urinary copper excretion, but white blood cell counts did not vary significantly.

TL;DR: The data suggest that physicians use 2.3 times the change in serum albumin, whereas those of Figge et al suggest 2.5; either approach gives similar results.

TL;DR: It is shown that the influenza vaccination causes transient changes in select markers of inflammation and lipids, and clinical and epidemiologic interpretation of the biomarkers affected should take into account the possible effects of influenza vaccination.

TL;DR: These PWA and modified TEG whole blood assays could prove useful for monitoring the reversal of clopidogrel and NSAID inhibition before surgery and could monitor the effectiveness for the individual patients with cardiovascular disease and help identify the need for alternative therapies.

TL;DR: Evidence indicates that physicians still display marked variability in ordering tests, and it is essential that physicians remain patient-centered, generate trust, and build a partnership with the patient to achieve consensus for medical decision-making.

TL;DR: Using complementary-DNA microarrays, 25 genes that were down-regulated by prenatal ethanol exposure on days 7 and 9 of gestation are identified and 6 have been identified and are discussed here in the context of the developing fetus.

TL;DR: The estimated incidence rates are imprecise because they were not collected through prospective surveillance systems, but the estimates for the 3 groups were internally consistent and provide useful information for clinicians.

TL;DR: The Th1 chemokines examined, especially IP-10, are comparable to IFN-γ as diagnostic markers of tuberculous and malignant pleural effusions, although IFn-γ is the most valuable.

TL;DR: The results of this investigation suggest that, within certain limitations for parameters derived or calculated from cellular volumes, blood specimens stored for as long as 24 hours at 4 degrees C may be suitable for hematologic testing.

TL;DR: This population-based study shows that a higher folate intake, in addition to other known constitutive and lifestyle factors, is significantly associated with a lower serum CRP concentration.

TL;DR: Serial measurements of serum cardiac markers and echocardiography in patients with de novo acute myeloid and lymphoid leukemias treated with anthracyclines are evaluated to aid the clinician in the treatment of patients by identifying high-risk patients who may benefit from closer observation or supportive cardiac therapy.

TL;DR: Investigation of the behavior and the diagnostic usefulness of D-dimer and factor VIII in cirrhotic patients with asymptomatic portal venous thrombosis shows that factor VIII values increase in severe cirrhosis but significantly decrease in the presence of concomitant portal thromBosis.

TL;DR: The data collectively demonstrate that HBX up-regulates the expression and activity of hTERT in hepatoma cells, suggesting that h TERT is associated with tumor development.

TL;DR: This is the first report showing that UCB-derived MSCs can express exogenous genes by way of a lentivirus vector, and demonstrates that human UCB is a source of mesenchymal progenitors and may be used in cell transplantation and a wide range of gene-therapy treatments.

TL;DR: The results of this research provide unequivocal evidence that SSVA is derived from SgI, and this form of amyloidosis is provisionally designated as ASgI.

TL;DR: The plasma level of osteopontin changes in a time-dependent fashion and is correlated with LV volumes and function and associated substantially with the extent of the inflammatory response indicated by the plasma hsCRP level and weakly with infarct size estimated on the basis of cardiac-enzyme release.

TL;DR: Levosimendan and dobutamine both improved postresuscitation myocardial function and increased the duration of postResuscitation survival.

TL;DR: It is shown that T-lymphocytes from the peripheral blood of subjects with severe and mild asthma differ in their gene-expression profiles, supporting the view that asthma is a systemic disease.

TL;DR: The results suggest that the serum level of cathepsin K could serve as a marker for fracture prediction and BMD.

TL;DR: Results indicate that tomato-based foods are especially beneficial in the prevention of platelet aggregation and thrombosis, and lycopene may inhibit the activation of phospholipase C, followed by inhibition of phosphoinositide breakdown andThromboxane B2 formation, thereby leading to inhibition of intracellular Ca+2 mobilization.

TL;DR: It is confirmed that albumin-derived and protein-derived peptides exist at high concentrations in urine and that the relative proportion of peptide excretion is significantly reduced compared with total protein.

TL;DR: It is hypothesized that reduction of ROS will reduce endothelial-cell activation and adhesion-molecule expression, thereby inhibiting vasoocclusion in sickle-cell disease and therapies to reduce oxidative stress will inhibit inflammation and vasoOCclusion in SCD.

TL;DR: The working hypothesis is that tetrathiomolybdate interrupts the inflammatory cascade at the activated-T-lymphocyte stage, and prevents doxorubicin toxicity in patients through the inhibition of interleukin-2.

TL;DR: The evaluation supports the use of this automated hematology analyzer method to measure total and differential WBC counts, which should aid clinical diagnosis and show good correlation with those obtained by the hemocytometer method.