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Showing papers in "Journal of Neuroscience Methods in 2012"


Journal ArticleDOI
TL;DR: In this paper, the authors proposed a template-based approach to match cortical landmarks of different subjects, which allows the selection of identical cortical regions of interest of desired size and location in different subjects with identification of the associated fiber tracts.

401 citations


Journal ArticleDOI
TL;DR: A number of multivariate methods appearing in previous multimodal fusion reports, mostly fMRI with other modality, which were performed with or without prior information are surveyed.

345 citations


Journal ArticleDOI
TL;DR: A novel method for the study of repetitive mild traumatic brain injury (rmTBI) that models the most common form of head injury in humans is presented and is ideal for high throughput screening of potential new therapies for mild concussive injuries as experienced by athletes and military personnel.

251 citations


Journal ArticleDOI
TL;DR: Through preliminary offline experiments and online experiments, it is confirmed that human SSVEPs elicited by visual flickering stimuli with a frequency resolution of 0.1 Hz could be classified with classification accuracy high enough to be used for a practical brain-computer interface (BCI) system.

225 citations


Journal ArticleDOI
TL;DR: Results show that the proposed epilepsy detection approach achieves not only high detection accuracy but also a very fast computation speed, which demonstrates its huge potential for the real-time detection of epileptic seizures.

225 citations


Journal ArticleDOI
TL;DR: The honey bee Apis mellifera has emerged as a robust and influential model for the study of classical conditioning thanks to the existence of a powerful Pavlovian conditioning protocol, the olfactory conditioning of the proboscis extension response (PER), and here a standardized framework for experiments using this behavioral protocol is defined.

197 citations


Journal ArticleDOI
TL;DR: It is shown that acausal high-pass filtering can generate a systematic bias easily leading to misinterpretations of neural activity, and that the early ERP component C1 is very sensitive to such effects.

158 citations


Journal ArticleDOI
TL;DR: This study examined the effect of group-size in the shoaling paradigm, and evaluated the ability of novel video-tracking tools to accurately track an entire shoal, compared to traditional manual analysis of shoaling phenotypes, demonstrating the capacity of video- tracking technology to assess zebrafish shoaling in a high-throughput and reliable manner.

151 citations


Journal ArticleDOI
TL;DR: This work reviews both formal and informal descriptions of a range of connectivity measures, suitable for the analysis of human brain electrophysiological data, principally electro- and magnetoencephalography, and introduces a novel set of cross-time-frequency measures.

144 citations


Journal ArticleDOI
TL;DR: In conclusion, maps of FDI muscle obtained at rest and during active contraction are very similar to each other in healthy individuals when differences in MT are taken into account.

133 citations


Journal ArticleDOI
TL;DR: The regional Fuzzy SLs discovered in this research can be used as reliable markers in neurofeedback treatments to improve neuronal plasticity and connectivity in autistic patients.

Journal ArticleDOI
TL;DR: NTMS combined with synchronized video recording provides an accurate monitoring tool of behavioral TMS experiments, and complete anomias, semantic, phonological and performance errors were observed during nTMS of left fronto-parieto-temporal cortical regions.

Journal ArticleDOI
TL;DR: This work developed a FACS procedure for dissociating intact cell bodies from adult wild-type rat brains and sorting them using commercially available antibodies against intracellular and extracellular proteins and allows rapid, high-throughput, quantitative assays of molecular alterations in identified cell types with widespread applications in neuroscience.

Journal ArticleDOI
TL;DR: REST-GCA was implemented on MATLAB as a graphical user interface (GUI) toolkit and tested the causal effect of the right frontal-insular cortex onto each voxel in the whole brain, and the transformation from F to F' and the further standardization from F' to Z score substantially improved the normality.

Journal ArticleDOI
TL;DR: A new measure to quantify circular-linear associations is introduced that leads to a robust estimate of the slope and phase offset of the regression line, and it provides a correlation coefficient for circular- linear data that is a natural analog of Pearson's product-moment correlation coefficientFor linear-linear data.

Journal ArticleDOI
TL;DR: The overall agreement and kappa coefficient of the proposed method applied to the all night polysomnography (PSG) of seventeen healthy subjects compared with the manual scorings by R&K rules can reach 86.68% and 0.79, respectively.

Journal ArticleDOI
TL;DR: An inexpensive but effective visual stimulator based on light emitting diodes (LEDs) and open-source Arduino microcontroller prototyping platform and to reduce design complexity allowing use of the system to end-users without advanced electronics skills is presented.

Journal ArticleDOI
TL;DR: IUE is combined with a binary piggyBac transposon system (PB-IUE), and it is shown that unlike conventional IUE, a single embryonic transfection of neocortical radial glia with a piggybac transPOSon system results in stable transgene expression in the neural lineage of radial glianes.

Journal ArticleDOI
TL;DR: The electrophysiological monetary incentive delay task (e-MID) is used to decompose the neural response to reinforcement anticipation, reinforcement-contingent target processing and feedback and provides a valuable complement to fMRI-based approaches to studying normal and abnormal brain correlates of reinforcement processing.

Journal ArticleDOI
TL;DR: Autoregressive (AR) models are used for feature extraction and characterization of EEG signals containing several kinds of subject-generated artifacts, suggesting that AR modeling can be a useful tool for discriminating among artifact signals both within and across individuals.

Journal ArticleDOI
TL;DR: This work has shown that sparse neurons are strongly affected by the maximum number of correctly identified neurons in Spike sorting algorithms, so further development of algorithms is needed to address sparse neurons detection.

Journal ArticleDOI
TL;DR: Results show that this new hybrid approach to BCI for continuous simultaneous two dimensional cursor control is viable for some users, and that substantial further research is needed to identify and optimize the best BCIs for each user.

Journal ArticleDOI
TL;DR: It is suggested that objective home monitoring of PD motor fluctuations is feasible and should be considered as a viable adjunct tool to provide insight into PD motor symptom response to treatment.

Journal ArticleDOI
TL;DR: This work calculated CMC between sensorimotor cortex EEG and EMG of two hand muscles during a key grip task in 14 healthy subjects and demonstrated that rectification is neither necessary nor appropriate in the calculation of CMC.

Journal ArticleDOI
TL;DR: The data show that impedance measurement is a convenient and reliable method for the detection of proliferation and kinetics of cell death in neuronal cell lines, whereas this method is less suitable for the assessment of neuronal differentiation and viability of primary neurons.

Journal ArticleDOI
TL;DR: A "combined" BCI based on P300 potentials and motion-onset visual evoked potentials (M-VEPs) is introduced and compared with BCIs based on each simple approach (P300 and M-VEP) to confirm that the combined approach is practical in an online BCI and yielded better performance than the other two approaches.

Journal ArticleDOI
TL;DR: A three-step strategy to automatically build reduced models of layer 5 pyramidal neurons that closely reproduce experimental data and can be applied to construct families of models of different neuron types, with applications ranging from the study of information processing in single neurons to realistic simulations of large-scale network dynamics.

Journal ArticleDOI
TL;DR: Test the performance of a synchronicity estimator widely applied in Neuroscience, phase lag index (PLI), for brain network inference in EEG shows that PLI is partially invariant to volume conduction, indicating that the high clustering shown by PLI networks are caused byVolume conduction.

Journal ArticleDOI
TL;DR: This work has developed a wireless neural recording technique that is capable of collecting single-unit data from chronically implanted multi-electrodes in freely moving marmosets and demonstrates the feasibility of using this method to study single neuron activity in freely roaming primates.

Journal ArticleDOI
TL;DR: This paper proposes a fully automated method of interictal spike detection that adapts to interpatient and intrapatient variation in spike morphology and shows little difference compared to the manual scoring of another expert for the spike-and-wave index evaluation in 17 additional records.