A Brief Overview of the WHO Classification of Breast Tumors, 4th Edition, Focusing on Issues and Updates from the 3rd Edition
Hans-Peter Sinn,Hans Kreipe +1 more
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This review of the WHO classification of Tumors of the Breast has focused on invasive carcinomas, precursor lesions, and some benign epithelial proliferations.Abstract:
The WHO Classification of Tumors of the Breast, 4th edition, is an update to the 3rd edition that was published in 2003, and covers all neoplastic and preneoplastic lesions of the breast. Changes to the 4th edition include new aspects and changes to the terminology that reflect our present-day knowledge of these lesions. Definitions for histopathological diagnosis are complemented by a description of clinical features, epidemiology, macroscopy, genetics, and prognostic and predictive features. In this review of the WHO classification, we have focused on invasive carcinomas, precursor lesions, and some benign epithelial proliferations.read more
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The antigenic link between thyroid autoimmunity and breast cancer.
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Three dimensional tumor models for cancer studies.
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Comparative histopathology and immunohistochemistry of human and canine mammary tumors.
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Breast carcinoma and phyllodes tumour: a case series
Eliza I-Lin Sin,Chow Yin Wong,Wei Sean Yong,Kong Wee Ong,Preetha Madhukumar,Veronique Kiak Mien Tan,Aye Aye Thike,Puay Hoon Tan,Benita Kiat Tee Tan +8 more
TL;DR: PT associated with carcinoma is rare, and it is often difficult to detect the presence of the carcinomatous component preoperatively, Hence, close examination of resected PT specimens must be carried out to allow prompt detection of any associated carcinomas, however rare, such that adequate treatment can be given.
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Upgrade Rate of Pure Flat Epithelial Atypia Diagnosed at Core Needle Biopsy: A Systematic Review and Meta-Analysis.
TL;DR: Surgical excision is recommended for pure flat epithelial atypia diagnosed at core needle biopsy, as the upgrade rate is greater than 2% as recommended by the Breast Imaging Reporting and Data System.
References
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TL;DR: This study showed poor long-term results of the posterior bone block procedure for posterior instability and a high rate of glenohumeral osteoarthritis although three patients with post-traumatic instability were pleased with the result of their operations.
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Atypical hyperplastic lesions of the female breast. A long-term follow-up study.
TL;DR: The authors conclude that among the epithelial hyperplastic lesions of the human breast, a minority may be recognized by their resemblance to CIS which have a clinically significant elevation of subsequent breast cancer risk.
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