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Open AccessJournal ArticleDOI

Acceleration of BMI in Early Childhood and Risk of Sustained Obesity.

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TLDR
Among obese adolescents, the most rapid weight gain had occurred between 2 and 6 years of age; most children who were obese at that age were obese in adolescence.
Abstract
Background The dynamics of body-mass index (BMI) in children from birth to adolescence are unclear, and whether susceptibility for the development of sustained obesity occurs at a specific...

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Obesity: global epidemiology and pathogenesis.

TL;DR: Although obesity prevalence increased in every single country in the world, regional differences exist in both obesity prevalence and trends; understanding the drivers of these regional differences might help to provide guidance on which are the most promising intervention strategies.
Journal ArticleDOI

Axes of a revolution: challenges and promises of big data in healthcare

TL;DR: The potential and challenges of using big data in healthcare resources are described, aiming to contribute to the ongoing discussion of the potential of big data resources to advance the understanding of health and disease.
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Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis

Arash Derakhshan, +52 more
TL;DR: Maternal subclinical hypothyroidism in pregnancy is associated with a higher risk of SGA and lower birthweight, whereas isolated hypothyroxinaemia is associatedwith lower risk ofSGA and higher birthweight.
References
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Journal ArticleDOI

Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014

TL;DR: In this nationally representative study of US children and adolescents aged 2 to 19 years, the prevalence of obesity in 2011-2014 was 17.0% and extreme obesity was 5.8%.
Journal ArticleDOI

Trajectories of growth among children who have coronary events as adults.

TL;DR: On average, adults who had a coronary event had been small at birth and thin at two years of age and thereafter put on weight rapidly and was associated with insulin resistance in later life.
Journal ArticleDOI

Adiposity rebound in children: a simple indicator for predicting obesity.

TL;DR: An early rebound (before 5.5 yr) is followed by a significantly higher adiposity level than a later rebound (after 7 yr), which is observed whatever the subject's adiposity at 1 yr.
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Body-Mass Index in 2.3 Million Adolescents and Cardiovascular Death in Adulthood

TL;DR: A BMI in the 50th to 74th percentiles, within the accepted normal range, during adolescence was associated with increased cardiovascular and all-cause mortality during 40 years of follow-up, and overweight and obesity were strongly associated with increase cardiovascular mortality in adulthood.
Journal ArticleDOI

Simulation of Growth Trajectories of Childhood Obesity into Adulthood

TL;DR: A simulation model to estimate the risk of adult obesity at the age of 35 years for the current population of children in the United States showed early development of obesity predicted obesity in adulthood, especially for children who were severely obese.
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