Proceedings ArticleDOI
Accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis. A study of 404 pulmonologists from 57 countries
Simon L.F. Walsh,David M. Hansell,Toby M. Maher,Richard Nusser,Margaret Wilsher,Venerino Poletti,Carlo Vancheri,Luca Richeldi,Paolo Spagnolo,Sara Tomassetti,Vincent Cottin,Bruno Crestani,Dominiue Valeyre,Hilario Nunes,Kevin K. Brown,Brett Ley,Fernando J. Martinez,Ganesh Raghu,Kevin R. Flaherty,Jan C. Grutters,Marlies S. Wijsenbeek,Hiroyuki Taniguchi,Yoshikazu Inoue,Yasuhiro Kondoh,Moisés Selman,Tamera J. Corte,Ian Glaspole,Martin Kolb,Kerri A. Johannson,Christopher J. Ryerson,Elisabeth Bendstrup,António Morais,Maria Molina Molina,Wim A. Wuyts,Juergen Behr,Michael Kreuter,Katerina M. Antoniou,Athol U. Wells,George Margaritopoulos,Maria Kokosi,Vasilis Kouranos,Eoin P. Judge +41 more
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TLDR
In this article, the authors conducted an international study of interstitial lung disease diagnosis among a large group of physicians and compared their diagnostic performance to a panel of experts (n=34).Abstract:
Methods: We conducted an international study of IPF diagnosis among a large group of physicians and compared their diagnostic performance to a panel of IPF experts (n=34). Participants evaluated 60 consecutive cases of interstitial lung disease. Diagnostic agreement was measured using weighted kappa coefficient (κw). Outcome distinctions between IPF and other diffuse lung diseases were used to validate diagnostic accuracy for first-choice diagnoses of IPF and were compared using the C-index. Results: 404 physicians completed the study. Agreement for IPF diagnosis was higher among expert physicians (κw =0.65 [IQR 0.53-0.72], P 20 years experience and MDT meeting attendance independently predicted prognostic accuracy of IPF diagnosis. The prognostic accuracy of academic physicians with >20 years experience (C-index=0.72, [IQR 0.0-0.73], p=0.229)) and non-university hospital physicians with more than 20 years experience, attending weekly MDT meetings (C-index=0.72, [IQR 0.70-0.72], p=0.052), did not differ significantly (p=0.229 and p=0.052 respectively) from the expert panel (C-index=0.74 [IQR 0.72-0.75]. Conclusion: Experienced respiratory physicians working at university-based institutions make diagnoses of IPF with similar prognostic accuracy to an international panel of IPF experts. Regular MDT meeting attendance improves the prognostic accuracy of experienced non-university practitioners to levels achieved by IPF experts.read more
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Journal ArticleDOI
Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry.
Michael Kreuter,Jeffrey J. Swigris,David Pittrow,S Geier,Jens Klotsche,Antje Prasse,Antje Prasse,Hubert Wirtz,Dirk Koschel,Stefan Andreas,Martin Claussen,Christian Grohé,H Wilkens,Lars Hagmeyer,Dirk Skowasch,Joachim F. Meyer,Joachim Kirschner,Sven Gläser,Felix J.F. Herth,Tobias Welte,Claus Neurohr,Martin Schwaiblmair,Matthias Held,Thomas Bahmer,Marion Frankenberger,Jürgen Behr +25 more
TL;DR: Overall, IPF patients under real-life conditions have lower QoL compared to those in clinical studies, andMultivariate analyses showed a significant association between QOL and IPF duration, FVC, age, NYHA class and indication for long-term oxygen treatment.
Journal ArticleDOI
European Respiratory Society International Congress 2017: highlights from the Clinical Assembly.
Nicolas Kahn,Evgeni Mekov,Laura Fregonese,Vasileios Andrianopoulos,Frits M.E. Franssen,Aleksandar Grgic,Johan Coolen,Peter I. Bonta,Daniela Gompelmann,Jouke T. Annema,Paola Faverio,Francesco Bonella,Luke Daines,H Pinnock,Janwillem W. H. Kocks,Felix J.F. Herth +15 more
TL;DR: In this comprehensive review, the newest research and actual data as well as award-winning abstracts and highlight sessions will be discussed.
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