Journal ArticleDOI
Acute toxicity of nano- and micro-scale zinc powder in healthy adult mice
Bing Wang,Weiyue Feng,Tian Cheng Wang,Guang Jia,Meng Wang,Jun Wen Shi,Fang Zhang,Yuliang Zhao,Zhifang Chai +8 more
TLDR
It is concluded that severe renal damage could occur in the N-Zn treated mice, though no significant change of blood biochemical levels occurred, which indicated that N- Zn powder could cause severe anemia.About:
This article is published in Toxicology Letters.The article was published on 2006-02-20. It has received 281 citations till now. The article focuses on the topics: Zinc toxicity & Toxicity.read more
Citations
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Journal ArticleDOI
Phytotoxicity of nanoparticles: Inhibition of seed germination and root growth
Daohui Lin,Baoshan Xing +1 more
TL;DR: Effects of five types of nanoparticles on seed germination and root growth of six higher plant species were investigated and inhibition on root growth varied greatly among nanoparticles and plants.
Journal ArticleDOI
NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials
Neenu Singh,Bella B. Manshian,Gareth J.S. Jenkins,Sioned M. Griffiths,Paul M. Williams,Thierry G.G. Maffeis,Chris J. Wright,Shareen H. Doak +7 more
TL;DR: Many of the engineered nanomaterials assessed were found to cause genotoxic responses, such as chromosomal fragmentation, DNA strand breakages, point mutations, oxidative DNA adducts and alterations in gene expression profiles.
Journal ArticleDOI
Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration.
Jiangxue Wang,Guoqiang Zhou,Chunying Chen,Hongwei Yu,Tiancheng Wang,Yongmei Ma,Guang Jia,Yuxi Gao,Bai Li,Jin Sun,Yufeng Li,Fang Jiao,Yuliang Zhao,Zhifang Chai +13 more
TL;DR: Biodistribution experiment showed that TiO(2) mainly retained in the liver, spleen, kidneys, and lung tissues, which indicated thatTiO( 2) particles could be transported to other tissues and organs after uptake by gastrointestinal tract.
Journal ArticleDOI
Review of health safety aspects of nanotechnologies in food production
Hans Bouwmeester,Susan Dekkers,M.Y. Noordam,Werner I. Hagens,A.S. Bulder,Cees de Heer,Sandra E.C.G. ten Voorde,Susan Wijnhoven,Hans J.P. Marvin,Adriënne J.A.M. Sips +9 more
TL;DR: An overview of scientific issues that need to be addressed with priority in order to improve the risk assessment of nanotechnologies and nanoparticles in food products is given.
Journal ArticleDOI
Metal-based nanoparticles and their toxicity assessment.
Amanda M. Schrand,Mohammad F. Rahman,Saber M. Hussain,John J. Schlager,David A. Smith,Ali F. Syed +5 more
TL;DR: There are many challenges to overcome before the authors can determine if the benefits outweigh the risks associated with NPs, and some metal-based NPs are showing increased toxicity, even if the same material is relatively inert in its bulk form.
References
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The potential environmental impact of engineered nanomaterials
TL;DR: With the increased presence of nanomaterials in commercial products, a growing public debate is emerging on whether the environmental and social costs of nanotechnology outweigh its many benefits.
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Fine Particulate Air Pollution and Mortality in 20 U.S. Cities, 1987–1994
TL;DR: In this article, the effects of five major outdoor-air pollutants on daily mortality rates in 20 of the largest cities and metropolitan areas in the United States from 1987 to 1994 were assessed, including PM10, ozone, carbon monoxide, sulfur dioxide, and nitrogen dioxide.
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Correlation between particle size, in vivo particle persistence, and lung injury
TL;DR: A comparison of the adverse reactions with dosimetric parameters of TiO2 in different lung compartments in the postexposure period showed a correlation of the persistence of effects in both the alveolar and interstitial space with theistence of particles in the respective compartment.
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OECD guidelines for testing of chemicals
TL;DR: This updated Test Guideline 430 provides an in vitro procedure allowing the identification of non-corrosive and corrosive substances and mixtures in accordance with UN GHS.
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Role of the alveolar macrophage in lung injury: studies with ultrafine particles.
TL;DR: In this paper, a series of experiments with ultrafine particles (approximately 20 nm) and larger particles (less than 200 nm) of "nuisance" dusts were conducted to evaluate the involvement of alveolar macrophages (AM) in particle-induced lung injury and particle translocation in rats.