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Open AccessJournal ArticleDOI

Adhesion-induced receptor segregation and adhesion plaque formation: A model membrane study

TLDR
A model system to study the control of cell adhesion by receptor-mediated specific forces, universal interactions, and membrane elasticity is established by reconstitution of homophilic receptor proteins into solid supported membranes and into giant vesicles with the polymers forming an artificial glycocalix.
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This article is published in Biophysical Journal.The article was published on 1999-10-01 and is currently open access. It has received 155 citations till now. The article focuses on the topics: Cell adhesion & Cell adhesion molecule.

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Polymer-supported membranes as models of the cell surface

TL;DR: This work focuses on lipid-bilayer membranes supported on solid substrates, which are widely used as cell-surface models that connect biological and artificial materials and when these systems are coupled with advanced semiconductor technology.
Journal ArticleDOI

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy.

TL;DR: Measurements are focused on a glycoprotein, contact site A, as a prototype of cell-adhesion proteins, expressed in aggregating cells of Dictyostelium discoideum, which are engaged in development of a multicellular organism.
Journal ArticleDOI

Contact mechanics and the adhesion of soft solids

TL;DR: In this paper, a review of the mechanics of contact experiments that are commonly used to characterize adhesion and the materials science of adhesion of elastic and viscoelastic materials is presented.
Journal ArticleDOI

Supported membranes on soft polymer cushions: fabrication, characterization and applications

TL;DR: In this paper, the authors applied powerful surface-sensitive techniques to study protein-protein recognition processes at membranes and the control of cell adhesion by the interplay of specific 'lock-and-key' forces and universal interfacial forces.
Journal ArticleDOI

Activation-independent platelet adhesion and aggregation under elevated shear stress

TL;DR: It is found that platelet and VWF modulation by hydrodynamic force is a mechanism for activation-independent aggregation that may support thrombotic arterial occlusion in patients with stenotic coronary arteries.
References
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Journal ArticleDOI

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

U. K. Laemmli
- 01 Jan 1970 - 
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Book

Physical chemistry of surfaces

TL;DR: In this paper, the authors discuss the nature and properties of liquid interfaces, including the formation of a new phase, nucleation and crystal growth, and the contact angle of surfaces of solids.
Journal ArticleDOI

Mobility measurement by analysis of fluorescence photobleaching recovery kinetics.

TL;DR: The theoretical basis and some practical guidelines for simple, rigorous analysis of FPR experiments are presented and some model experiments on aqueous solutions of rhodamine 6G are described.
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