Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN').
Kim Solez,Robert B. Colvin,Lorraine C. Racusen,Banu Sis,Philip F. Halloran,Patricia E. Birk,Patricia Campbell,Marilia Cascalho,A. B. Collins,Anthony J. Demetris,Cinthia B. Drachenberg,Ian W. Gibson,Paul C. Grimm,Mark Haas,Evelyne Lerut,Helen Liapis,Roslyn B. Mannon,P. B. Marcus,Michael Mengel,Michael J. Mihatsch,Brian J. Nankivell,Volker Nickeleit,John C. Papadimitriou,Jeffrey L. Platt,Parmjeet Randhawa,Ian Roberts,L. Salinas-Madriga,Daniel R. Salomon,Daniel Serón,M. Sheaff,Jan J. Weening +30 more
TLDR
The 8th Banff Conference on Allograft Pathology was held in Edmonton, Canada, 15–21 July 2005, and major outcomes included the elimination of the non‐specific term ‘chronic allograft nephropathy’ (CAN) and the recognition of the entity of chronic antibody‐mediated rejection.About:
This article is published in American Journal of Transplantation.The article was published on 2007-03-01 and is currently open access. It has received 1036 citations till now. The article focuses on the topics: Chronic allograft nephropathy & Transplant glomerulopathy.read more
Citations
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Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions
Kim Solez,Robert B. Colvin,Lorraine C. Racusen,Mark Haas,Banu Sis,Michael Mengel,Philip F. Halloran,William M. Baldwin,G. Banfi,A. B. Collins,Fernando G. Cosio,D. S. R. David,Cinthia B. Drachenberg,Gunilla Einecke,Agnes B. Fogo,Ian W. Gibson,Denis Glotz,Samy S. Iskandar,Edward S. Kraus,Evelyne Lerut,Roslyn B. Mannon,Michael J. Mihatsch,Brian J. Nankivell,Volker Nickeleit,John C. Papadimitriou,Parmjeet Randhawa,Heinz Regele,Karine Renaudin,Ian S.D. Roberts,Daniel Serón,Rex Neal Smith,Marialuisa Valente +31 more
TL;DR: Emerging research data led to the establishment of collaborative working groups addressing issues like isolated ‘v’ lesion and incorporation of omics‐technologies, paving the way for future combination of graft biopsy and molecular parameters within the Banff process.
Journal ArticleDOI
Calcineurin Inhibitor Nephrotoxicity
TL;DR: The authors critically review the current evidence relating systemic blood levels of cyclosporine and tacrolimus to calcineurin inhibitor nephrotoxicity, and summarize the data suggesting that local exposure to cycloporine or tacolimus could be more important than systemic exposure.
Journal ArticleDOI
Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence.
Joana Sellarés,D. G. de Freitas,Michael Mengel,Jeff Reeve,Gunilla Einecke,Banu Sis,Luis G. Hidalgo,Konrad S. Famulski,Arthur J. Matas,Philip F. Halloran +9 more
TL;DR: This prospective cohort indicates that many actual failures after indication biopsies manifest phenotypic features of antibody‐mediated or mixed rejection and also underscores the major role of nonadherence.
Journal ArticleDOI
Identifying Specific Causes of Kidney Allograft Loss
Ziad M. El-Zoghby,Mark D. Stegall,Donna J. Lager,Walter K. Kremers,Hatem Amer,James M. Gloor,Fernando G. Cosio +6 more
TL;DR: Targets for investigation and intervention are identified that may result in improved kidney transplantation outcomes and alloinmunity remains the most common mechanism leading to failure.
Journal ArticleDOI
Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation.
Brian D. Tait,Caner Süsal,Howard M. Gebel,Peter Nickerson,Andrea A. Zachary,Frans H.J. Claas,Elaine F. Reed,Robert A. Bray,Patricia Campbell,Jeremy R. Chapman,P. Toby Coates,Robert B. Colvin,Emanuele Cozzi,Ilias I.N. Doxiadis,Susan V. Fuggle,John S. Gill,Denis Glotz,Nils Lachmann,Thalachallour Mohanakumar,Nicole Suciu-Foca,Suchitra Sumitran-Holgersson,Kazunari Tanabe,Craig J. Taylor,Dolly B. Tyan,Angela C Webster,Adriana Zeevi,Gerhard Opelz +26 more
TL;DR: A group of laboratory and clinical experts in the field of transplantation was convened to prepare a consensus report and make recommendations on the use of this new technology based on both published evidence and expert opinion.
References
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Journal ArticleDOI
The Banff 97 working classification of renal allograft pathology
Lorraine C. Racusen,Kim Solez,Robert B. Colvin,Stephen M. Bonsib,Maria Castro,Tito Cavallo,Byron P. Croker,A. Jake Demetris,Cynthia B. Drachenberg,Agnes B. Fogo,Peter N. Furness,Lillian W. Gaber,Ian W. Gibson,Dennis Glotz,J. Goldberg,Joseph P. Grande,Philip F. Halloran,H.E. Hansen,Barry Hartley,Pekka Hayry,Claire M. Hill,Ernesto O. Hoffman,Lawrence G. Hunsicker,Anne S. Lindblad,Niels Marcussen,M. J. Mihatsch,Tibor Nadasdy,Peter Nickerson,T. Steen Olsen,John C. Papadimitriou,Parmjeet Randhawa,David C. Rayner,Ian S.D. Roberts,Stephen Rose,D. Rush,Luis Salinas-Madrigal,Daniel R. Salomon,Stale Sund,Eero Taskinen,Kiril Trpkov,Yutaka Yamaguchi +40 more
TL;DR: Major changes include the following: rejection with vasculitis is separated from tubulointerstitial rejection; severe rejection requires transmural changes in arteries; "borderline" rejection can only be interpreted in a clinical context; antibody-mediated rejection is further defined, and lesion scoring focuses on most severely involved structures.
Journal ArticleDOI
Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection.
Lorraine C. Racusen,Robert B. Colvin,Kim Solez,Michael J. Mihatsch,Philip F. Halloran,Patricia Campbell,Michael Cecka,Jean Pierre Cosyns,Anthony J. Demetris,Michael C. Fishbein,Agnes B. Fogo,Peter N. Furness,Ian W. Gibson,Denis Glotz,Pekka Häyry,Lawrence Hunsickern,Michael Kashgarian,Ronald H. Kerman,Alex J. Magil,Robert A. Montgomery,Kunio Morozumi,Volker Nickeleit,Parmjeet Randhawa,Heinz Regele,Daniel Serón,Surya V. Seshan,Stale Sund,Kiril Trpkov +27 more
TL;DR: This article presents international consensus criteria for and classification of AbAR developed based on discussions held at the Sixth Banff Conference on Allograft Pathology in 2001, to be revisited as additional data accumulate in this important area of renal transplantation.
Journal ArticleDOI
Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling.
Minnie M. Sarwal,Mei-Sze Chua,Neeraja Kambham,Szu-Chuan Hsieh,Thomas Satterwhite,Marilyn Masek,Oscar Salvatierra +6 more
TL;DR: Systematic analysis of gene-expression patterns provides a window on the biology and pathogenesis of renal allograft rejection, and reveals a striking association between dense CD20+ B-cell infiltrates and both clinical glucocorticoid resistance and graft loss.
Journal ArticleDOI
Chronic Humoral Rejection: Identification of Antibody-Mediated Chronic Renal Allograft Rejection by C4d Deposits in Peritubular Capillaries
Shamila Mauiyyedi,Patricia Della Pelle,Susan L. Saidman,A. Bernard Collins,Manuel Pascual,Nina Tolkoff-Rubin,Winfred W. Williams,A. Benedict Cosimi,Eveline E. Schneeberger,Robert B. Colvin +9 more
TL;DR: C4d can be used to separate this group of CR from the nonspecific category of chronic allograft nephropathy and may have the potential to guide successful therapeutic intervention and support the hypothesis that a substantial fraction of CR is mediated by antibody (immunologically active).
Journal ArticleDOI
Antibody-mediated organ-allograft rejection
Robert B. Colvin,R. Neal Smith +1 more
TL;DR: Antibody induces rejection acutely through the fixation of complement, resulting in tissue injury and coagulation, and complement activation recruits macrophages and neutrophils, causing additional endothelial injury.
Related Papers (5)
The Banff 97 working classification of renal allograft pathology
Lorraine C. Racusen,Kim Solez,Robert B. Colvin,Stephen M. Bonsib,Maria Castro,Tito Cavallo,Byron P. Croker,A. Jake Demetris,Cynthia B. Drachenberg,Agnes B. Fogo,Peter N. Furness,Lillian W. Gaber,Ian W. Gibson,Dennis Glotz,J. Goldberg,Joseph P. Grande,Philip F. Halloran,H.E. Hansen,Barry Hartley,Pekka Hayry,Claire M. Hill,Ernesto O. Hoffman,Lawrence G. Hunsicker,Anne S. Lindblad,Niels Marcussen,M. J. Mihatsch,Tibor Nadasdy,Peter Nickerson,T. Steen Olsen,John C. Papadimitriou,Parmjeet Randhawa,David C. Rayner,Ian S.D. Roberts,Stephen Rose,D. Rush,Luis Salinas-Madrigal,Daniel R. Salomon,Stale Sund,Eero Taskinen,Kiril Trpkov,Yutaka Yamaguchi +40 more
Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions
Kim Solez,Robert B. Colvin,Lorraine C. Racusen,Mark Haas,Banu Sis,Michael Mengel,Philip F. Halloran,William M. Baldwin,G. Banfi,A. B. Collins,Fernando G. Cosio,D. S. R. David,Cinthia B. Drachenberg,Gunilla Einecke,Agnes B. Fogo,Ian W. Gibson,Denis Glotz,Samy S. Iskandar,Edward S. Kraus,Evelyne Lerut,Roslyn B. Mannon,Michael J. Mihatsch,Brian J. Nankivell,Volker Nickeleit,John C. Papadimitriou,Parmjeet Randhawa,Heinz Regele,Karine Renaudin,Ian S.D. Roberts,Daniel Serón,Rex Neal Smith,Marialuisa Valente +31 more
Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection.
Lorraine C. Racusen,Robert B. Colvin,Kim Solez,Michael J. Mihatsch,Philip F. Halloran,Patricia Campbell,Michael Cecka,Jean Pierre Cosyns,Anthony J. Demetris,Michael C. Fishbein,Agnes B. Fogo,Peter N. Furness,Ian W. Gibson,Denis Glotz,Pekka Häyry,Lawrence Hunsickern,Michael Kashgarian,Ronald H. Kerman,Alex J. Magil,Robert A. Montgomery,Kunio Morozumi,Volker Nickeleit,Parmjeet Randhawa,Heinz Regele,Daniel Serón,Surya V. Seshan,Stale Sund,Kiril Trpkov +27 more
International standardization of criteria for the histologic diagnosis of renal allograft rejection : the Banff working classification of kidney transplant pathology
Kim Solez,Roy A. Axelsen,Hallgrimur Benediktsson,James F. Burdick,Arthur H. Cohen,Robert B. Colvin,Byron P. Croker,Dominique Droz,Michael S. Dunnill,Philip F. Halloran,Pekka Häyry,J. Charles Jennette,Paul Keown,Niels Marcussen,Michael J. Mihatsch,Kunio Morozumi,Bryan D. Myers,Cynthia C. Nast,Steen Olsen,Lorraine C. Racusen,E L Ramos,Seymour Rosen,David H. Sachs,Daniel R. Salomon,Fred Sanfilippo,Regina R. Verani,Eeva von Willebrand,Yutaka Yamaguchi +27 more