Bioavailability of the polyphenols: status and controversies.
TLDR
In the present review, a critical overview on the difficulties and the controversies of the studies on the bioavailability of the polyphenols is discussed.Abstract:
The current interest in polyphenols has been driven primarily by epidemiological studies. However, to establish conclusive evidence for the effectiveness of dietary polyphenols in disease prevention, it is useful to better define the bioavailability of the polyphenols, so that their biological activity can be evaluated. The bioavailability appears to differ greatly among the various phenolic compounds, and the most abundant ones in our diet are not necessarily those that have the best bioavailability profile. In the present review, we focus on the factors influencing the bioavailability of the polyphenols. Moreover, a critical overview on the difficulties and the controversies of the studies on the bioavailability is discussed.read more
Citations
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Phenolic compounds in Brassica vegetables.
TL;DR: The significance of phenolic compounds as a source of beneficial compounds for human health and the influence of environmental conditions and processing mechanisms on the phenolic composition of Brassica vegetables are reviewed.
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Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties
TL;DR: This paper revises and discusses these antimicrobial activities of dietary polyphenols and their relevance for human health, shedding light on the importance of polyphenol structure recognition by specific enzymes produced by intestinal microbial taxa.
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Resources and biological activities of natural polyphenols.
TL;DR: This review summarizes current knowledge of natural polyphenols, including resource, bioactivities, bioavailability and potential toxicity.
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Phenolic compounds in fruits – an overview
Charles Windson Isidoro Haminiuk,Giselle Maria Maciel,Manuel Salvador Vicente Plata-Oviedo,Rosane Marina Peralta +3 more
TL;DR: In this paper, the most recent articles dealing with polyphenols in fruits are reviewed, focusing on their occurrence, main methods of extraction, quantification and antioxidant assays, and the health benefits and bioaccessibility/bioavailability of phenolic compounds in fruits.
Journal ArticleDOI
Dietary factors affecting polyphenol bioavailability
TL;DR: Increased knowledge of the factors affecting polyphenol bioavailability, including dietary factors, is paramount and polyphenols may act synergistically due to their influence on efflux transporters such as p-glycoprotein.
References
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Journal ArticleDOI
Polyphenols: food sources and bioavailability
TL;DR: The nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed, and bioavailability appears to differ greatly between the variousPolyphenols, and the most abundantpolyphenols in the authors' diet are not necessarily those that have the best bioavailability profile.
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Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
TL;DR: Gallic acid and isoflavones are the most well-absorbed polyphenols, followed by catechins, flavanones, and quercetin glucosides, but with different kinetics, and the least well- absorption polyphenol are the proanthocyanidins, the galloylated tea catech ins, andThe anthocyanins.
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Dietary Intake and Bioavailability of Polyphenols
TL;DR: Both chemical and biochemical factors that affect the absorption and metabolism of polyphenols are reviewed, with particular emphasis on flavonoid glycosides.
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Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study.
Michael G. L. Hertog,Daan Kromhout,Christ Aravanis,Henry Blackburn,Ratko Buzina,Flaminio Fidanza,Simona Giampaoli,Annemarie Jansen,Alessandro Menotti,Alessandro Menotti,Srecko Nedeljkovic,Maija Pekkarinen,Bozidar S. Simic,Hironori Toshima,Edith J. M. Feskens,Peter C. H. Hollman,Martijn B. Katan +16 more
TL;DR: Average flavonoid intake may partly contribute to differences in coronary heart disease mortality across populations, but it does not seem to be an important determinant of cancer mortality.
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Polyphenols and disease risk in epidemiologic studies
TL;DR: A review of available epidemiologic data on the health effects of polyphenols, focusing on the flavonoid subclasses of flavonols, flavones, and catechins and on lignans, is presented in this paper.