Brain (re)organisation following amputation: Implications for phantom limb pain
Tamar R. Makin,Herta Flor +1 more
TLDR
The need to consider potential contributions of additional brain mechanisms, beyond S1 remapping, and the dynamic interplay of contextual factors with brain changes for understanding and alleviating PLP is highlighted.About:
This article is published in NeuroImage.The article was published on 2020-05-16 and is currently open access. It has received 70 citations till now. The article focuses on the topics: Phantom limb & Brain activity and meditation.read more
Citations
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Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury
Thomas Elbert,Herta Flor,Niels Birbaumer,Stefan Knecht,S. Hampson,Wolfgang Larbig,Edward Taub +6 more
TL;DR: In this article, magnetic source imaging revealed that the topographic representation in the somatosensory cortex of upper extremity amputees was shifted an average of 1.5 cm toward the area that would normally receive input from the now absent nerves supplying the hand and fingers.
Journal ArticleDOI
Neural encoding of actual and imagined touch within human posterior parietal cortex
Srinivas Chivukula,Srinivas Chivukula,Carey Y. Zhang,Tyson Aflalo,Matiar Jafari,Matiar Jafari,Kelsie Pejsa,Nader Pouratian,Nader Pouratian,Richard A. Andersen +9 more
TL;DR: These results are the first neuron level evidence of touch encoding in human PPC and its cognitive engagement during tactile imagery which may reflect semantic processing, sensory anticipation, and imagined touch.
Journal ArticleDOI
Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial.
Muhammed Enes Gunduz,Muhammed Enes Gunduz,Kevin Pacheco-Barrios,Kevin Pacheco-Barrios,Kevin Pacheco-Barrios,Camila Bonin Pinto,Camila Bonin Pinto,Dante Duarte,Dante Duarte,Dante Duarte,Faddi Ghassan Saleh Velez,Faddi Ghassan Saleh Velez,Faddi Ghassan Saleh Velez,Anna Carolyna Lepesteur Gianlorenco,Anna Carolyna Lepesteur Gianlorenco,Anna Carolyna Lepesteur Gianlorenco,Paulo E P Teixeira,Paulo E P Teixeira,Stefano Giannoni-Luza,Stefano Giannoni-Luza,David Crandell,Linamara Rizzo Battistella,Marcel Simis,Felipe Fregni,Felipe Fregni +24 more
TL;DR: In this article, the effects of transcranial direct current stimulation (tDCS) and mirror therapy (MT) in patients with traumatic lower limb amputation were assessed in a factorial trial.
Journal ArticleDOI
Review of the Role of the Brain in Chemotherapy-Induced Peripheral Neuropathy.
Maryam Omran,Elizabeth Belcher,Nimish Mohile,Shelli R. Kesler,Michelle C. Janelsins,Andrea G. Hohmann,Ian R. Kleckner +6 more
TL;DR: In this paper, the role of the brain in CIPN was investigated, and the authors discussed how to leverage this knowledge for future preclinical research, clinical research, and brain-based treatments.
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Simultaneous control of natural and extra degrees of freedom by isometric force and electromyographic activity in the muscle-to-force null space
Sergio Gurgone,Daniele Borzelli,Paolo de Pasquale,Denise J. Berger,Tommaso Lisini Baldi,Nicole D'Aurizio,Domenico Prattichizzo,Andrea d’Avella +7 more
TL;DR: An information-theoretic metric, an index of difficulty defined as the sum of a spatial and a temporal term, is developed to assess individual null space control ability for both reaching and holding.
References
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Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation
Herta Flor,Thomas Elbert,Stefan Knecht,Christian Wienbruch,Christo Pantev,Niels Birbaumer,Wolfgang Larbig,Edward Taub +7 more
TL;DR: A very strong direct relationship is reported between the amount of cortical reorganization and the magnitude of phantom limb pain (but not non-painful phantom phenomena) experienced after arm amputation, indicating that phantom-limb pain is related to, and may be a consequence of, plastic changes in primary somatosensory cortex.