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Chitosan-PVP-nano silver oxide wound dressing: In vitro and in vivo evaluation

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TLDR
The prepared chitosan-PVP-nano silver oxide (CPS) films were characterized for their thermal behaviour, morphological properties, mechanical properties, antibacterial properties and wound healing properties and found higher antibacterial activity.
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This article is published in International Journal of Biological Macromolecules.The article was published on 2015-02-01. It has received 283 citations till now. The article focuses on the topics: Silver Nano & Silver oxide.

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Advanced Therapeutic Dressings for Effective Wound Healing—A Review

TL;DR: In this article, the current state of wound healing and wound management products, with emphasis on the demand for more advanced forms of wound therapy and some of the current challenges and driving forces behind this demand, are reviewed.
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Chitosan based hydrogels and their applications for drug delivery in wound dressings: A review

TL;DR: Applications and structural characteristics of different types of active ingredients, such as growth factors, nanoparticles, nanostructures, and drug loaded chitosan hydrogels are summarized.
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Chitosan as a Wound Dressing Starting Material: Antimicrobial Properties and Mode of Action

TL;DR: The antimicrobial properties of chitosan are reviewed and the mechanisms of action toward microbial cells as well as the interactions with mammalian cells in terms of wound healing process are described.
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Enhanced antibacterial and wound healing activities of microporous chitosan-Ag/ZnO composite dressing

TL;DR: In vivo evaluation in mice reveals that the in vivo evaluation of the novel chitosan-Ag/ZnO composite dressing enhances the wound healing and promotes re-epithelialization and collagen deposition and strongly support the possibility of using it for wound care application.
Journal Article

The use of physical hydrogels of chitosan for skin regeneration following third-degree burns

TL;DR: The aim of the study was at assessing whether this material was totally accepted by the host organism and allowed in vivo skin reconstruction of limited area third-degree burns and showed that chitosan materials were well tolerated and promoted a good tissue regeneration.
References
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Journal ArticleDOI

The bactericidal effect of silver nanoparticles

TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.
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Antimicrobial effects of silver nanoparticles

TL;DR: The results suggest that Ag nanoparticles can be used as effective growth inhibitors in various microorganisms, making them applicable to diverse medical devices and antimicrobial control systems.
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A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus.

TL;DR: The existence of elements of silver and sulfur in the electron-dense granules and cytoplasm detected by X-ray microanalysis suggested the antibacterial mechanism of silver: DNA lost its replication ability and the protein became inactivated after Ag(+) treatment.
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Biomaterials based on chitin and chitosan in wound dressing applications

TL;DR: The purpose of this review is to take a closer look on the wound dressing applications of biomaterials based on chitin, chitosan and their derivatives in various forms in detail.
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Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties.

TL;DR: This study demonstrated for the first time, the application of polyphosphate as a hemostatic adjuvant, and developed a new chitosan-based composite with potent he mostatic and antimicrobial properties.
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