Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men
Eleanor L. Watts,Paul N. Appleby,Demetrius Albanes,Amanda Black,June M. Chan,Chu Chen,Piera M. Cirillo,Barbara A. Cohn,Michael B. Cook,Jenny L Donovan,Luigi Ferrucci,Cedric F. Garland,Graham G. Giles,Graham G. Giles,Phyllis J. Goodman,Laurel A. Habel,Christopher A. Haiman,Jeffrey M P Holly,Robert N. Hoover,Rudolf Kaaks,Paul Knekt,Laurence N. Kolonel,Tatsuhiko Kubo,Loic Le Marchand,Tapio Luostarinen,Robert J. MacInnis,Robert J. MacInnis,Hanna Mäenpää,Satu Männistö,E. Jeffrey Metter,Roger L. Milne,Roger L. Milne,Abraham M. Y. Nomura,Steven E. Oliver,J. Kellogg Parsons,Petra H.M. Peeters,Petra H.M. Peeters,Elizabeth A. Platz,Elio Riboli,Fulvio Ricceri,Sabina Rinaldi,Harri Rissanen,Norie Sawada,Catherine Schaefer,Jeannette M. Schenk,Frank Z. Stanczyk,Meir J. Stampfer,Pär Stattin,Ulf-Håkan Stenman,Anne Tjønneland,Antonia Trichopoulou,Ian M. Thompson,Shoichiro Tsugane,Lars J. Vatten,Alice S. Whittemore,Regina G. Ziegler,Naomi E. Allen,Timothy J. Key,Ruth C. Travis +58 more
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TLDR
Circulating sex hormones in men are strongly associated with age and body mass index, and to a lesser extent with smoking status and alcohol consumption.Abstract:
Introduction: Sex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis ...read more
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The accelerated aging phenotype: The role of race and social determinants of health on aging
TL;DR: The early appearance and increased severity of age-associated disease among African American and low socioeconomic status (SES) individuals suggests that the factors contributing to the emergence of health disparities may also induce a phenotype of "premature aging" or "accelerated aging", which may proceed on a different trajectory than the overall population as discussed by the authors .
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Interaction between diet- and exercise-lifestyle and phthalates exposure on sex hormone levels.
Jiafei Zhang,Wenjun Yin,Pei Li,Chen Hu,Lu Wang,Tian Li,Erwei Gao,Jian Hou,Guiyang Wang,Xian Wang,Lin Wang,Zhiqiang Yu,Jing Yuan +12 more
TL;DR: High urinary mono-(2-ethyl-5-oxyhexyl) phthalate (MEOHP) levels and no exercise had an additive interaction on abnormal serum progesterone (PROG) levels in winter as well as on abnormally high serum follicle-stimulating hormone (FSH) or luteinizing hormone (LH) Levels in summer.
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Androgens and prostate cancer risk: a prospective study
TL;DR: A nested case-control study of 392 cases and 392 matched controls found no significant associations between androgen levels and risk of prostate cancer in this population-based, non-screened cohort.
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Sleep restriction and testosterone concentrations in young healthy males: randomized controlled studies of acute and chronic short sleep
TL;DR: Sleep restriction does not adversely affect plasma testosterone levels in healthy young men and confirmatory studies should be done to ascertain the influence of sleep duration and quality on testosterone concentrations in men throughout life.
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Effects of Dietary or Supplementary Micronutrients on Sex Hormones and IGF-1 in Middle and Older Age: A Systematic Review and Meta-Analysis.
Ryan Janjuha,Diane Bunn,Richard P. G. Hayhoe,Lee Hooper,Asmaa Abdelhamid,Shaan Mahmood,Joseph Hayden-Case,Will Appleyard,Sophie Morris,Ailsa A Welch +9 more
TL;DR: A systematic review of RCTs investigating effects of increasing dietary or supplemental micronutrient intake on sex hormones and IGF-1 in individuals aged 45 years or older found all trials had significant methodological limitations making effects of micronsutrient supplementation onsex hormones unclear.
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Barry S. Taylor,Nikolaus Schultz,Haley Hieronymus,Anuradha Gopalan,Yonghong Xiao,Brett S. Carver,Vivek K. Arora,Poorvi Kaushik,Ethan Cerami,Boris Reva,Yevgeniy Antipin,Nicholas Mitsiades,Thomas Landers,Igor Dolgalev,John E. Major,Manda Wilson,Nicholas D. Socci,Alex E. Lash,Adriana Heguy,James A. Eastham,Howard I. Scher,Victor E. Reuter,Peter T. Scardino,Chris Sander,Charles L. Sawyers,Charles L. Sawyers,William L. Gerald +26 more
TL;DR: Analysis of genomic and clinical outcome data from 218 prostate cancer tumors revealed that copy-number alterations robustly define clusters of low- and high-risk disease beyond that achieved by Gleason score.
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Age Trends in the Level of Serum Testosterone and Other Hormones in Middle-Aged Men: Longitudinal Results from the Massachusetts Male Aging Study
Henry A. Feldman,Christopher Longcope,Carol A. Derby,Catherine B. Johannes,Andre B. Araujo,Andrea D. Coviello,William J. Bremner,John B. McKinlay +7 more
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Transport of Steroid Hormones: Binding of 21 Endogenous Steroids to Both Testosterone-Binding Globulin and Corticosteroid-Binding Globulin in Human Plasma
TL;DR: A model of steroid transport in human plasma is described, finding that normal men, normal women during both the follicular and luteal phases of the ovarian cycle, and women during the third trimester of a normal pregnancy are candidates for steroid transport.
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