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Robert J. MacInnis
Researcher at Cancer Council Victoria
Publications - 210
Citations - 16343
Robert J. MacInnis is an academic researcher from Cancer Council Victoria. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 52, co-authored 190 publications receiving 12107 citations. Previous affiliations of Robert J. MacInnis include Royal Melbourne Hospital & University of Western Australia.
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Journal ArticleDOI
Body-Mass Index and Mortality among 1.46 Million White Adults
Amy Berrington de Gonzalez,Patricia Hartge,James R. Cerhan,Alan J. Flint,Lindsay M. Hannan,Robert J. MacInnis,Robert J. MacInnis,Steven C. Moore,Geoffrey S. Tobias,Hoda Anton-Culver,Laura E. Beane Freeman,W. Lawrence Beeson,Sandra Clipp,Dallas R. English,Aaron R. Folsom,D. Michal Freedman,Graham G. Giles,Niclas Håkansson,Katherine D. Henderson,Judith Hoffman-Bolton,Jane A. Hoppin,Karen L. Koenig,I. Min Lee,Martha S. Linet,Yikyung Park,Gaia Pocobelli,Arthur Schatzkin,Howard D. Sesso,Elisabete Weiderpass,Bradley J. Willcox,Alicja Wolk,Anne Zeleniuch-Jacquotte,Walter C. Willett,Michael J. Thun +33 more
TL;DR: In white adults, overweight and obesity (and possibly underweight) are associated with increased all-cause mortality and the hazard ratios for the men were similar.
Journal ArticleDOI
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants
Nilah M. Ioannidis,Joseph H. Rothstein,Joseph H. Rothstein,Vikas Pejaver,Sumit Middha,Shannon K. McDonnell,Saurabh Baheti,Anthony M. Musolf,Qing Li,Emily R. Holzinger,Danielle M. Karyadi,Lisa A. Cannon-Albright,Craig C. Teerlink,Janet L. Stanford,William B. Isaacs,Jianfeng Xu,Kathleen A. Cooney,Kathleen A. Cooney,Ethan M. Lange,Johanna Schleutker,John D. Carpten,Isaac J. Powell,Olivier Cussenot,Geraldine Cancel-Tassin,Graham G. Giles,Graham G. Giles,Robert J. MacInnis,Robert J. MacInnis,Christiane Maier,Chih-Lin Hsieh,Fredrik Wiklund,William J. Catalona,William D. Foulkes,Diptasri Mandal,Rosalind A. Eeles,Zsofia Kote-Jarai,Carlos Bustamante,Daniel J. Schaid,Trevor Hastie,Elaine A. Ostrander,Joan E. Bailey-Wilson,Predrag Radivojac,Stephen N. Thibodeau,Alice S. Whittemore,Weiva Sieh,Weiva Sieh +45 more
TL;DR: This work developed REVEL (rare exome variant ensemble learner), an ensemble method for predicting the pathogenicity of missense variants on the basis of individual tools: MutPred, FATHMM, VEST, PolyPhen, SIFT, PROVEAN, MutationAssessor, LRT, GERP, SiPhy, phyloP, and phastCons.
Journal ArticleDOI
Association analysis identifies 65 new breast cancer risk loci
Kyriaki Michailidou,Kyriaki Michailidou,Sara Lindström,Sara Lindström,Joe Dennis,Jonathan Beesley,Shirley Hui,Siddhartha Kar,Audrey Lemaçon,Penny Soucy,Dylan M. Glubb,Asha Rostamianfar,Manjeet K. Bolla,Qin Wang,Jonathan Tyrer,Ed Dicks,Andy C. H. Lee,Zhaoming Wang,Jamie Allen,Renske Keeman,Ursula Eilber,Juliet D. French,Xiaoqing Chen,Laura Fachal,Karen McCue,Amy E. McCart Reed,Maya Ghoussaini,Jason S. Carroll,Xia Jiang,Hilary K. Finucane,Hilary K. Finucane,Marcia Adams,Muriel A. Adank,Habibul Ahsan,Kristiina Aittomäki,Hoda Anton-Culver,Natalia Antonenkova,Volker Arndt,Kristan J. Aronson,Banu Arun,Paul L. Auer,Paul L. Auer,Francois Bacot,Myrto Barrdahl,Caroline Baynes,Matthias W. Beckmann,Sabine Behrens,Javier Benitez,Marina Bermisheva,Leslie Bernstein,Carl Blomqvist,Natalia Bogdanova,Stig E. Bojesen,Stig E. Bojesen,Bernardo Bonanni,Anne Lise Børresen-Dale,Judith S. Brand,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Paul Brennan,Hermann Brenner,Louise A. Brinton,Per Broberg,Ian W. Brock,Annegien Broeks,Angela Brooks-Wilson,Angela Brooks-Wilson,Sara Y. Brucker,Thomas Brüning,Barbara Burwinkel,Barbara Burwinkel,Katja Butterbach,Qiuyin Cai,Hui Cai,Trinidad Caldés,Federico Canzian,Angel Carracedo,Brian D. Carter,Jose E. Castelao,Tsun Leung Chan,Tongguang Cheng,Kee Seng Chia,Ji Yeob Choi,Hans Christiansen,Christine L. Clarke,Margriet Collée,Don M. Conroy,Emilie Cordina-Duverger,Sten Cornelissen,David G. Cox,David G. Cox,Angela Cox,Simon S. Cross,Julie M. Cunningham,Kamila Czene,Mary B. Daly,Peter Devilee,Kimberly F. Doheny,Thilo Dörk,Isabel dos-Santos-Silva,Martine Dumont,Lorraine Durcan,Miriam Dwek,Diana Eccles,Arif B. Ekici,A. Heather Eliassen,A. Heather Eliassen,Carolina Ellberg,Mingajeva Elvira,Christoph Engel,Mikael Eriksson,Peter A. Fasching,Peter A. Fasching,Jonine D. Figueroa,Dieter Flesch-Janys,Olivia Fletcher,Henrik Flyger,Lin Fritschi,Valerie Gaborieau,Marike Gabrielson,Manuela Gago-Dominguez,Yu Tang Gao,Susan M. Gapstur,José A. García-Sáenz,Mia M. Gaudet,Vassilios Georgoulias,Graham G. Giles,Graham G. Giles,Gord Glendon,Mark S. Goldberg,David E. Goldgar,Anna González-Neira,Grethe I. Grenaker Alnæs,Mervi Grip,Jacek Gronwald,Anne Grundy,Pascal Guénel,Lothar Haeberle,Eric Hahnen,Christopher A. Haiman,Niclas Håkansson,Ute Hamann,N Hamel,Susan E. Hankinson,Patricia Harrington,Steven N. Hart,Jaana M. Hartikainen,Mikael Hartman,Mikael Hartman,Alexander Hein,Jane Heyworth,Belynda Hicks,Peter Hillemanns,Dona N. Ho,Antoinette Hollestelle,Maartje J. Hooning,Robert N. Hoover,John L. Hopper,Ming-Feng Hou,Chia-Ni Hsiung,Guanmengqian Huang,Keith Humphreys,Junko Ishiguro,Hidemi Ito,Motoki Iwasaki,Hiroji Iwata,Anna Jakubowska,Wolfgang Janni,Esther M. John,Esther M. John,Nichola Johnson,Kristine Jones,Michael Jones,Arja Jukkola-Vuorinen,Rudolf Kaaks,Maria Kabisch,Katarzyna Kaczmarek,Daehee Kang,Daehee Kang,Yoshio Kasuga,Michael J. Kerin,Sofia Khan,Elza Khusnutdinova,Elza Khusnutdinova,Johanna I. Kiiski,Sung-Won Kim,Julia A. Knight,Julia A. Knight,Veli-Matti Kosma,Vessela N. Kristensen,Vessela N. Kristensen,Ute Krüger,Ava Kwong,Diether Lambrechts,Loic Le Marchand,Eunjung Lee,Min Hyuk Lee,Jong Won Lee,Chuen Neng Lee,Flavio Lejbkowicz,Jingmei Li,Jenna Lilyquist,Annika Lindblom,Jolanta Lissowska,Wing-Yee Lo,Wing-Yee Lo,Sibylle Loibl,Jirong Long,Artitaya Lophatananon,Artitaya Lophatananon,Jan Lubinski,Craig Luccarini,Michael P. Lux,Edmond S. K. Ma,Robert J. MacInnis,Robert J. MacInnis,Tom Maishman,Enes Makalic,Kathleen E. Malone,Ivana Maleva Kostovska,Arto Mannermaa,Siranoush Manoukian,JoAnn E. Manson,JoAnn E. Manson,Sara Margolin,Shivaani Mariapun,Maria Elena Martinez,Keitaro Matsuo,Dimitrios Mavroudis,James McKay,Catriona McLean,Hanne Meijers-Heijboer,Alfons Meindl,Primitiva Menéndez,Usha Menon,J.-P. Meyer,Hui Miao,Nicola Miller,Nur Aishah Taib,Kenneth Muir,Kenneth Muir,Anna Marie Mulligan,Anna Marie Mulligan,Claire Mulot,Susan L. Neuhausen,Heli Nevanlinna,Patrick Neven,Sune F. Nielsen,Dong-Young Noh,Børge G. Nordestgaard,Børge G. Nordestgaard,Aaron D. Norman,Olufunmilayo I. Olopade,Janet E. Olson,Håkan Olsson,Curtis Olswold,Nick Orr,V. Shane Pankratz,Sue K. Park,Sue K. Park,Tjoung-Won Park-Simon,Rachel Lloyd,Jose Ignacio Arias Perez,Paolo Peterlongo,Julian Peto,Kelly-Anne Phillips,Mila Pinchev,Dijana Plaseska-Karanfilska,Ross L. Prentice,Nadege Presneau,Darya Prokofyeva,Elizabeth W. Pugh,Katri Pylkäs,Brigitte Rack,Paolo Radice,Nazneen Rahman,Gadi Rennert,Hedy S. Rennert,Valerie Rhenius,Atocha Romero,Jane Romm,Kathryn J. Ruddy,Thomas Rüdiger,Anja Rudolph,Matthias Ruebner,Emiel J. Th. Rutgers,Emmanouil Saloustros,Dale P. Sandler,Suleeporn Sangrajrang,Elinor J. Sawyer,Daniel F. Schmidt,Rita K. Schmutzler,Andreas Schneeweiss,Minouk J. Schoemaker,Fredrick R. Schumacher,Peter Schürmann,Rodney J. Scott,Rodney J. Scott,Christopher G. Scott,Sheila Seal,Caroline Seynaeve,Mitul Shah,Priyanka Sharma,Chen-Yang Shen,Chen-Yang Shen,Grace Sheng,Mark E. Sherman,Martha J. Shrubsole,Xiao-Ou Shu,Ann Smeets,Christof Sohn,Melissa C. Southey,John J. Spinelli,John J. Spinelli,Christa Stegmaier,Sarah Stewart-Brown,Jennifer Stone,Jennifer Stone,Daniel O. Stram,Harald Surowy,Harald Surowy,Anthony J. Swerdlow,Rulla M. Tamimi,Rulla M. Tamimi,Jack A. Taylor,Maria Tengström,Soo Hwang Teo,Mary Beth Terry,Daniel C. Tessier,Somchai Thanasitthichai,Kathrin Thöne,Rob A. E. M. Tollenaar,Ian Tomlinson,Ling Tong,Diana Torres,Diana Torres,Thérèse Truong,Chiu-Chen Tseng,Shoichiro Tsugane,Hans-Ulrich Ulmer,Giske Ursin,Michael Untch,Celine M. Vachon,Christi J. van Asperen,David Van Den Berg,Ans M.W. van den Ouweland,Lizet E. van der Kolk,Rob B. van der Luijt,Daniel Vincent,Jason Vollenweider,Quinten Waisfisz,Shan Wang-Gohrke,Clarice R. Weinberg,Camilla Wendt,Alice S. Whittemore,Hans Wildiers,Walter C. Willett,Robert Winqvist,Alicja Wolk,Anna H. Wu,Lucy Xia,Taiki Yamaji,Xiaohong R. Yang,Cheng Har Yip,Keun-Young Yoo,Jyh-Cherng Yu,Wei Zheng,Ying Zheng,Bin Zhu,Argyrios Ziogas,Elad Ziv,Sunil R. Lakhani,Sunil R. Lakhani,Antonis C. Antoniou,Arnaud Droit,Irene L. Andrulis,Irene L. Andrulis,Christopher I. Amos,Fergus J. Couch,Paul D.P. Pharoah,Jenny Chang-Claude,Jenny Chang-Claude,Per Hall,David J. Hunter,Roger L. Milne,Roger L. Milne,Montserrat Garcia-Closas,Marjanka K. Schmidt,Stephen J. Chanock,Alison M. Dunning,Stacey L. Edwards,Gary D. Bader,Georgia Chenevix-Trench,Jacques Simard,Peter Kraft,Douglas F. Easton +396 more
TL;DR: A genome-wide association study of breast cancer in 122,977 cases and 105,974 controls of European ancestry and 14,068 cases and 13,104 controls of East Asian ancestry finds that heritability of Breast cancer due to all single-nucleotide polymorphisms in regulatory features was 2–5-fold enriched relative to the genome- wide average.
Journal ArticleDOI
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Nasim Mavaddat,Kyriaki Michailidou,Kyriaki Michailidou,Joe Dennis,Michael Lush,Laura Fachal,Andrew Lee,Jonathan Tyrer,Ting Huei Chen,Qin Wang,Manjeet K. Bolla,Xin Yang,Muriel A. Adank,Thomas U. Ahearn,Kristiina Aittomäki,Jamie Allen,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Natalia Antonenkova,Volker Arndt,Kristan J. Aronson,Paul L. Auer,Paul L. Auer,Päivi Auvinen,Myrto Barrdahl,Laura E. Beane Freeman,Matthias W. Beckmann,Sabine Behrens,Javier Benitez,Marina Bermisheva,Leslie Bernstein,Carl Blomqvist,Carl Blomqvist,Natalia Bogdanova,Stig E. Bojesen,Stig E. Bojesen,Bernardo Bonanni,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale,Hiltrud Brauch,Hiltrud Brauch,Hiltrud Brauch,Michael Bremer,Hermann Brenner,Adam R. Brentnall,Ian W. Brock,Angela Brooks-Wilson,Angela Brooks-Wilson,Sara Y. Brucker,Thomas Brüning,Barbara Burwinkel,Barbara Burwinkel,Daniele Campa,Daniele Campa,Brian D. Carter,Jose E. Castelao,Stephen J. Chanock,Rowan T. Chlebowski,Hans Christiansen,Christine L. Clarke,J. Margriet Collée,Emilie Cordina-Duverger,Sten Cornelissen,Fergus J. Couch,Angela Cox,Simon S. Cross,Kamila Czene,Mary B. Daly,Peter Devilee,Thilo Dörk,Isabel dos-Santos-Silva,Martine Dumont,Lorraine Durcan,Miriam Dwek,Diana Eccles,Arif B. Ekici,A. Heather Eliassen,A. Heather Eliassen,Carolina Ellberg,Christoph Engel,Mikael Eriksson,D. Gareth Evans,Peter A. Fasching,Peter A. Fasching,Jonine D. Figueroa,Jonine D. Figueroa,Olivia Fletcher,Henrik Flyger,Asta Försti,Asta Försti,Lin Fritschi,Marike Gabrielson,Manuela Gago-Dominguez,Susan M. Gapstur,José A. García-Sáenz,Mia M. Gaudet,Vassilios Georgoulias,Graham G. Giles,Graham G. Giles,Graham G. Giles,I. R. Gilyazova,I. R. Gilyazova,Gord Glendon,Mark S. Goldberg,David E. Goldgar,Anna González-Neira,Grethe I. Grenaker Alnæs,Mervi Grip,Jacek Gronwald,Anne Grundy,Pascal Guénel,Lothar Haeberle,Eric Hahnen,Christopher A. Haiman,Niclas Håkansson,Ute Hamann,Susan E. Hankinson,Elaine F. Harkness,Elaine F. Harkness,Steven N. Hart,Wei He,Alexander Hein,Jane Heyworth,Peter Hillemanns,Antoinette Hollestelle,Maartje J. Hooning,Robert N. Hoover,John L. Hopper,Anthony Howell,Guanmengqian Huang,Keith Humphreys,David J. Hunter,David J. Hunter,Milena Jakimovska,Anna Jakubowska,Anna Jakubowska,Wolfgang Janni,Esther M. John,Nichola Johnson,Michael Jones,Arja Jukkola-Vuorinen,Audrey Y. Jung,Rudolf Kaaks,Katarzyna Kaczmarek,Vesa Kataja,Renske Keeman,Michael J. Kerin,Elza Khusnutdinova,Elza Khusnutdinova,Johanna I. Kiiski,Julia A. Knight,Julia A. Knight,Yon-Dschun Ko,Veli-Matti Kosma,Stella Koutros,Vessela N. Kristensen,Vessela N. Kristensen,Ute Krüger,Tabea Kühl,Diether Lambrechts,Loic Le Marchand,Eunjung Lee,Flavio Lejbkowicz,Jenna Lilyquist,Annika Lindblom,Sara Lindström,Sara Lindström,Jolanta Lissowska,Wing-Yee Lo,Wing-Yee Lo,Sibylle Loibl,Jirong Long,Jan Lubinski,Michael P. Lux,Robert J. MacInnis,Robert J. MacInnis,Tom Maishman,Enes Makalic,Ivana Maleva Kostovska,Arto Mannermaa,Siranoush Manoukian,Sara Margolin,John W.M. Martens,Maria Elena Martinez,Dimitrios Mavroudis,Catriona McLean,Alfons Meindl,Usha Menon,Pooja Middha,Pooja Middha,Nicola Miller,Fernando Salvador Moreno,Anna Marie Mulligan,Anna Marie Mulligan,Claire Mulot,Victor Muñoz-Garzón,Susan L. Neuhausen,Heli Nevanlinna,Patrick Neven,William G. Newman,Sune F. Nielsen,Børge G. Nordestgaard,Børge G. Nordestgaard,Aaron D. Norman,Kenneth Offit,Janet E. Olson,Håkan Olsson,Nick Orr,V. Shane Pankratz,Tjoung-Won Park-Simon,Jose Ignacio Arias Perez,Clara Pérez-Barrios,Paolo Peterlongo,Julian Peto,Mila Pinchev,Dijana Plaseska-Karanfilska,Eric C. Polley,Ross L. Prentice,Nadege Presneau,Darya Prokofyeva,Kristen S. Purrington,Katri Pylkäs,Brigitte Rack,Paolo Radice,Rohini Rau-Murthy,Gad Rennert,Hedy S. Rennert,Valerie Rhenius,Mark E. Robson,Atocha Romero,Kathryn J. Ruddy,Matthias Ruebner,Emmanouil Saloustros,Dale P. Sandler,Elinor J. Sawyer,Daniel F. Schmidt,Daniel F. Schmidt,Rita K. Schmutzler,Andreas Schneeweiss,Minouk J. Schoemaker,Fredrick R. Schumacher,Peter Schürmann,Lukas Schwentner,Christopher G. Scott,Rodney J. Scott,Rodney J. Scott,Caroline Seynaeve,Mitul Shah,Mark E. Sherman,Martha J. Shrubsole,Xiao-Ou Shu,Susan L. Slager,Ann Smeets,Christof Sohn,Penny Soucy,Melissa C. Southey,Melissa C. Southey,John J. Spinelli,Christa Stegmaier,Jennifer Stone,Jennifer Stone,Anthony J. Swerdlow,Rulla M. Tamimi,Rulla M. Tamimi,William J. Tapper,Jack A. Taylor,Mary Beth Terry,Kathrin Thöne,Rob A. E. M. Tollenaar,Ian Tomlinson,Ian Tomlinson,Thérèse Truong,Maria Tzardi,Hans-Ulrich Ulmer,Michael Untch,Celine M. Vachon,Elke M van Veen,Joseph Vijai,Clarice R. Weinberg,Camilla Wendt,Alice S. Whittemore,Hans Wildiers,Walter C. Willett,Walter C. Willett,Robert Winqvist,Alicja Wolk,Alicja Wolk,Xiaohong R. Yang,Drakoulis Yannoukakos,Yan Zhang,Wei Zheng,Argyrios Ziogas,Alison M. Dunning,Deborah J. Thompson,Georgia Chenevix-Trench,Jenny Chang-Claude,Jenny Chang-Claude,Marjanka K. Schmidt,Per Hall,Roger L. Milne,Roger L. Milne,Roger L. Milne,Paul D.P. Pharoah,Antonis C. Antoniou,Nilanjan Chatterjee,Nilanjan Chatterjee,Peter Kraft,Montserrat Garcia-Closas,Jacques Simard,Douglas F. Easton +310 more
TL;DR: This PRS, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset is developed and empirically validated and is a powerful and reliable predictor of breast cancer risk that may improve breast cancer prevention programs.
Journal ArticleDOI
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
Fredrick R. Schumacher,Ali Amin Al Olama,Sonja I. Berndt,Sara Benlloch,Mahbubl Ahmed,Edward J. Saunders,Tokhir Dadaev,Daniel Leongamornlert,Ezequiel Anokian,Clara Cieza-Borrella,Chee Goh,Mark N. Brook,Xin Sheng,Laura Fachal,Joe Dennis,Jonathan Tyrer,Kenneth Muir,Kenneth Muir,Artitaya Lophatananon,Artitaya Lophatananon,Victoria L. Stevens,Susan M. Gapstur,Brian D. Carter,Catherine M. Tangen,Phyllis J. Goodman,Ian M. Thompson,Jyotsna Batra,Jyotsna Batra,Suzanne K. Chambers,Suzanne K. Chambers,Leire Moya,Leire Moya,Judith A. Clements,Judith A. Clements,Lisa G. Horvath,Wayne D. Tilley,Gail P. Risbridger,Gail P. Risbridger,Henrik Grönberg,Markus Aly,Tobias Nordström,Paul D.P. Pharoah,Nora Pashayan,Johanna Schleutker,Teuvo L.J. Tammela,Csilla Sipeky,Anssi Auvinen,Demetrius Albanes,Stephanie J. Weinstein,Alicja Wolk,Alicja Wolk,Niclas Håkansson,Catharine M L West,Alison M. Dunning,Neil G. Burnet,Lorelei A. Mucci,Edward Giovannucci,Gerald L. Andriole,Olivier Cussenot,Geraldine Cancel-Tassin,Stella Koutros,Laura E. Beane Freeman,Karina Dalsgaard Sørensen,Torben F. Ørntoft,Michael Borre,Lovise Maehle,Eli Marie Grindedal,David E. Neal,David E. Neal,David E. Neal,Jenny L Donovan,Freddie C. Hamdy,Richard M. Martin,Ruth C. Travis,Timothy J. Key,Robert J. Hamilton,Neil E. Fleshner,Antonio Finelli,Sue A. Ingles,Mariana C. Stern,Barry S. Rosenstein,Sarah L. Kerns,Harry Ostrer,Yong-Jie Lu,Hongwei Zhang,Ninghan Feng,Xueying Mao,Xin Guo,Guomin Wang,Zan Sun,Graham G. Giles,Melissa C. Southey,Robert J. MacInnis,Robert J. MacInnis,Liesel M. FitzGerald,Liesel M. FitzGerald,Adam S. Kibel,Bettina F. Drake,Ana Vega,Antonio Gómez-Caamaño,Robert Szulkin,Martin Eklund,Manolis Kogevinas,Javier Llorca,Gemma Castaño-Vinyals,Kathryn L. Penney,Meir J. Stampfer,Jong Y. Park,Thomas A. Sellers,Hui Yi Lin,Janet L. Stanford,Janet L. Stanford,Cezary Cybulski,Dominika Wokołorczyk,Jan Lubinski,Elaine A. Ostrander,Milan S. Geybels,Børge G. Nordestgaard,Sune F. Nielsen,Maren Weischer,Rasmus Bisbjerg,Martin Andreas Røder,Peter Iversen,Hermann Brenner,Katarina Cuk,Bernd Holleczek,Christiane Maier,Manuel Luedeke,Thomas J. Schnoeller,Jeri Kim,Christopher J. Logothetis,Esther M. John,Esther M. John,Manuel R. Teixeira,Manuel R. Teixeira,Paula Paulo,Marta Cardoso,Susan L. Neuhausen,Linda Steele,Yuan Chun Ding,Kim De Ruyck,Gert De Meerleer,Piet Ost,Azad Hassan Abdul Razack,Jasmine Lim,Soo Hwang Teo,Daniel W. Lin,Daniel W. Lin,Lisa F. Newcomb,Lisa F. Newcomb,Davor Lessel,Marija Gamulin,Tomislav Kuliš,Radka Kaneva,Nawaid Usmani,Nawaid Usmani,Sandeep Singhal,Sandeep Singhal,Chavdar Slavov,Vanio Mitev,Matthew Parliament,Matthew Parliament,Frank Claessens,Steven Joniau,Thomas Van den Broeck,Samantha E.T. Larkin,Paul A. Townsend,Claire Aukim-Hastie,Manuela Gago Dominguez,Jose Esteban Castelao,Maria Elena Martinez,Monique J. Roobol,Guido Jenster,Ron H.N. van Schaik,Florence Menegaux,Thérèse Truong,Yves Akoli Koudou,Jianfeng Xu,Kay-Tee Khaw,Lisa A. Cannon-Albright,Lisa A. Cannon-Albright,Hardev Pandha,Agnieszka Michael,Stephen N. Thibodeau,Shannon K. McDonnell,Daniel J. Schaid,Sara Lindström,Constance Turman,Jing Ma,David J. Hunter,Elio Riboli,A. Siddiq,Federico Canzian,Laurence N. Kolonel,Loic Le Marchand,Robert N. Hoover,Mitchell J. Machiela,Zuxi Cui,Peter Kraft,Christopher I. Amos,David V. Conti,Douglas F. Easton,Fredrik Wiklund,Stephen J. Chanock,Brian E. Henderson,Zsofia Kote-Jarai,Christopher A. Haiman,Rosalind A. Eeles +207 more
TL;DR: A large meta-analysis combining genome-wide and custom high-density genotyping array data identifies 63 new susceptibility loci for prostate cancer, enhancing fine-mapping efforts and providing insights into the underlying biology of PrCa1.