Journal ArticleDOI
Concepts in diagnosis and therapy for male reproductive impairment
TLDR
This paper reviews the hormonal assessments and specific genetic analyses that are useful additional tests, and detail other evidence-based examinations that are available to help guide therapeutic strategies.About:
This article is published in The Lancet Diabetes & Endocrinology.The article was published on 2017-07-01. It has received 95 citations till now. The article focuses on the topics: Intracytoplasmic sperm injection & Reproductive technology.read more
Citations
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Journal ArticleDOI
The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities
Christopher L.R. Barratt,Lars Björndahl,Christopher J. De Jonge,Dolores J. Lamb,Francisco Osorio Martini,Robert I McLachlan,Robert D. Oates,Sheryl van der Poel,Sheryl van der Poel,Bianca St John,Mark Sigman,Rebecca Z. Sokol,Herman Tournaye +12 more
TL;DR: The consensus guideline methodology is described, the evidence-based recommendations provided to the World Health Organization for their consideration in the development of global guidance are summarized and a narrative review of the diagnosis of male infertility as related to the eight prioritized PICO questions is presented.
Journal ArticleDOI
Clinical Management of Congenital Hypogonadotropic Hypogonadism
Jacques Young,Jacques Young,Cheng Xu,Georgios Papadakis,James S Acierno,Luigi Maione,Luigi Maione,Johanna Hietamäki,Taneli Raivio,Nelly Pitteloud +9 more
TL;DR: This review is a comprehensive synthesis of the current literature available regarding the diagnosis, patient management, and genetic foundations of CHH relative to normal reproductive development.
Journal ArticleDOI
Infectious, inflammatory and ‘autoimmune’ male factor infertility: how do rodent models inform clinical practice?
Monika Fijak,Adrian Pilatz,Mark P. Hedger,Nour Nicolas,Sudhanshu Bhushan,Vera Michel,Kenneth S. K. Tung,Hans-Christian Schuppe,Andreas Meinhardt +8 more
TL;DR: This is the first comprehensive review of rodent models of both infectious and autoimmune disease of testis/epididymis, and their clinical implications, and clear evidence that models mimicking testicular and/or epididymal inflammation and infection have been instructive in a better understanding of the mechanisms of disease initiation and progression.
Journal ArticleDOI
Sperm recovery and ICSI outcomes in men with non-obstructive azoospermia: a systematic review and meta-analysis
Giovanni Corona,Suks Minhas,Aleksander Giwercman,Carlo Bettocchi,Marij Dinkelman-Smit,Gert R. Dohle,Ferdinando Fusco,Ates Kadioglou,Sabine Kliesch,Zsolt Kopa,Csilla Krausz,Fiore Pelliccione,Alessandro Pizzocaro,Jens Rassweiler,Paolo Verze,Linda Vignozzi,Wolfgang Weidner,Mario Maggi,Nikolaos Sofikitis +18 more
TL;DR: Meta-regression analysis demonstrated that SRR per cycle was independent of age and hormonal parameters at enrolment, but the SRR increased as a function of testis volume, while micro-TESE/mTESE in subjects with NOA results in SRRs of up to 50%, with no differences when cTESE was compared to mTESE.
Journal ArticleDOI
Disorders of spermatogenesis: Perspectives for novel genetic diagnostics after 20 years of unchanged routine.
TL;DR: Significant breakthroughs concerning the genetics of male infertility will be achieved in the near future and will translate into clinical routine to improve patient/couple care, according to the authors.
References
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Journal ArticleDOI
Reproductive Technologies and the Risk of Birth Defects
Michael J. Davies,Vivienne M. Moore,Kristyn Willson,Phillipa Van Essen,Kevin Priest,Heather Scott,Eric Haan,Annabelle Chan +7 more
TL;DR: The increased risk of birth defects associated with IVF was no longer significant after adjustment for parental factors, and the risk of ICSI remained increased after multivariate adjustment, although the possibility of residual confounding cannot be excluded.
Journal ArticleDOI
Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment
Ulrich Boehm,Pierre Bouloux,Mehul T. Dattani,Nicolas de Roux,Catherine Dodé,Leo Dunkel,Andrew A. Dwyer,Paolo Giacobini,J.-P. Hardelin,Anders Juul,Mohamad Maghnie,Nelly Pitteloud,Vincent Prevot,Taneli Raivio,Manuel Tena-Sempere,Richard Quinton,Jacques Young +16 more
TL;DR: A timely diagnosis and treatment to induce puberty can be beneficial for sexual, bone and metabolic health, and might help minimize some the psychological effects of CHH.
Book
WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Male
TL;DR: The manual for the standardized investigation and diagnosis of the infertile couple is one of the literary work in this world in suitable to be reading material and will show the amazing benefits of reading a book.
Journal ArticleDOI
Antioxidants for male subfertility
Marian Showell,Rebecca Mackenzie-Proctor,Julie Brown,Anusch Yazdani,Marcin T Stankiewicz,Roger Hart +5 more
TL;DR: This Cochrane review aimed to evaluate the effectiveness and safety of oral supplementation with antioxidants for subfertile male partners in couples seeking fertility assistance with a placebo, no treatment or another antioxidant.