Journal ArticleDOI
Cucurbituril chemistry: a tale of supramolecular success
Reads0
Chats0
TLDR
Cucurbit[n]urils have become key units in various self-organizing and stimulus-controlled assemblies, as well as in advanced materials and drug carriers.Abstract:
This review highlights the past six year advances in the blossoming field of cucurbit[n]uril chemistry. Because of their exceptional recognition properties in aqueous medium, these pumpkin-shaped macrocycles have been generating some tremendous interest in the supramolecular community. They have also become key units in various self-organizing and stimulus-controlled assemblies, as well as in advanced materials and drug carriers. The scope of this review is limited to the main family of cucurbit[n]urils (n = 5, 6, 7, 8, 10). The reader will find an overview of their preparation, their physicochemical and biological properties, as well as their recognition abilities towards various organic and inorganic guests. Detailed thermodynamic and kinetic considerations, as well as multiple applications including supramolecular catalysis are also discussed.read more
Citations
More filters
Journal ArticleDOI
Cucurbit[7]uril complexations of bis(isoquinolinium)alkane dications in aqueous solution
TL;DR: In this article, the 1:1 and 2:1 host-guest complexation of a series of 1,n-bis(isoquinolinium)alkane dications (Iq(CH2)nIq2+, n = 2, 4, 5, 6, 8, 9, 10 and 12) in aqueous solution has been investigated by 1H NMR spectroscopy and ESI mass spectrometry.
Journal ArticleDOI
A General Picture of Cucurbit[8]uril Host-Guest Binding: Recalibrating Bonded Interactions.
TL;DR: In this article , a thorough evaluation of the remaining parts of classical force fields, i.e., the bonded interactions, was performed, and two widely used fixed-charge models for drug-like molecules were investigated and compared in great detail, aiming at providing guidelines in choosing an appropriate charge scheme in host-guest modelling.
Journal ArticleDOI
Synthesis of 2-Methylresorcinol-Based Deepened Cavitands with Chiral Inlet Bearing Steroidal Moieties on the Upper Rim
Journal ArticleDOI
Anion control in the complexation of cucurbit[6]uril with Cu(II) salts
TL;DR: Based on the coordination ability of SCN−, Cl− and NO3, three coordination complexes were synthesized through the reaction of cucurbit[6]uril (Q[6]) with transition metal ion Cu(II) at different anion conditions.
Book ChapterDOI
Advances in the Development of Supramolecular Polymeric Biomaterials
TL;DR: It is proposed that supramolecular materials that are composed of macromers and oligomers which are held together via noncovalent interactions are perfectly suitable to meet requirements to closely mimic the ECM in a synthetic fashion.
References
More filters
Journal ArticleDOI
Complexation Thermodynamics of Cyclodextrins.
Journal ArticleDOI
The cucurbit[n]uril family
TL;DR: In 1981, the macrocyclic methylene-bridged glycoluril hexamer (CB[6]) was dubbed "cucurbituril" by Mock and co-workers because of its resemblance to the most prominent member of the cucurbitaceae family of plants--the pumpkin.
Journal ArticleDOI
Cucurbituril homologues and derivatives: new opportunities in supramolecular chemistry.
TL;DR: This Account is a compilation of recent literature covering the syntheses of the homologues and derivatives, and their supramolecular chemistry of cucurbituril, a synthetic receptor.
Journal ArticleDOI
New Cucurbituril Homologues: Syntheses, Isolation, Characterization, and X-ray Crystal Structures of Cucurbit[n]uril (n = 5, 7, and 8)
Jaheon Kim,In-Sun Jung,Soo Young Kim,Eunsung Lee,Jin-Koo Kang,Shigeru Sakamoto,and Kentaro Yamaguchi,Kimoon Kim +7 more
Journal ArticleDOI
Nanotechnology in Drug Delivery and Tissue Engineering: From Discovery to Applications
TL;DR: Two important aspects of nanomedicine, drug delivery and tissue engineering are discussed, highlighting the advances the authors have recently experienced, the challenges they are currently facing, and what they are likely to witness in the near future.
Related Papers (5)
Cucurbiturils: from synthesis to high-affinity binding and catalysis
Khaleel I. Assaf,Werner M. Nau +1 more