Journal ArticleDOI
Cucurbituril chemistry: a tale of supramolecular success
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TLDR
Cucurbit[n]urils have become key units in various self-organizing and stimulus-controlled assemblies, as well as in advanced materials and drug carriers.Abstract:
This review highlights the past six year advances in the blossoming field of cucurbit[n]uril chemistry. Because of their exceptional recognition properties in aqueous medium, these pumpkin-shaped macrocycles have been generating some tremendous interest in the supramolecular community. They have also become key units in various self-organizing and stimulus-controlled assemblies, as well as in advanced materials and drug carriers. The scope of this review is limited to the main family of cucurbit[n]urils (n = 5, 6, 7, 8, 10). The reader will find an overview of their preparation, their physicochemical and biological properties, as well as their recognition abilities towards various organic and inorganic guests. Detailed thermodynamic and kinetic considerations, as well as multiple applications including supramolecular catalysis are also discussed.read more
Citations
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In Search of Preferential Macrocyclic Hosts for Sulfur Mustard Sensing and Recognition: A Computational Investigation through the New Composite Method r2SCAN-3c of the Key Factors Influencing the Host-Guest Interactions
Fatine Ali Messiad,Nesrine Ammouchi,Youghourta Belhocine,Hanan Alhussain,M. G. Ghoniem,Ridha Ben Said,Fatima Adam Mohamed Ali,Seyfeddine Rahali +7 more
TL;DR: In this article , the authors investigated the interactions of sulfur mustard and its derivatives with a variety of host macrocycles through molecular docking calculations and non-covalent interaction (NCI) analysis and found that dispersion interactions contributed significantly to the overall complexation energy.
Posted Content
Ionization of Cucurbiturils as a Pathway to More Stable Host-Guest Complexes
TL;DR: It is asserted that the ionization of cucurbiturils fosters C60 – cucur Bituril binding due to significant polarization of electron density in C60, and suggests a previously unexplored pathway to additionally increase stability of the host–guest complexes.
Journal ArticleDOI
Structural Features of the Inclusion Compound Based on the trans-[Co(en)2Cl2]+ Complex and Cucurbit[8]Uril: A DFT Study
TL;DR: In this paper, structural features of the inclusion compound based on the cobalt(III) trans-[Co(en)2Cl2]+ complex and the cucurbit[8]uril macrocycle are studied within the density functional theory.
Journal ArticleDOI
Thermodynamic study of ethanol impact on gemcitabine binding to cucurbit[7]uril in aqueous solutions
TL;DR: In this article, the process of complexation of gemcitabine cation by cucurbituril Q7 was studied in an aqueous formate buffer with increasing ethanol mass fraction wEtOH using ITC calorimetric titration technique.
Journal ArticleDOI
Use of Graphene and Cucurbit[7]uril Electrodes for the Determination of Amantadine in Biological Fluids
Carmen Domínguez,Pedro Hernández +1 more
TL;DR: In this paper, a differential pulse voltammetry (DPV) method for amantadine (AT) determination was developed, where all the chemical and instrumental variables affecting the determination were optimized.
References
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Journal ArticleDOI
Complexation Thermodynamics of Cyclodextrins.
Journal ArticleDOI
The cucurbit[n]uril family
TL;DR: In 1981, the macrocyclic methylene-bridged glycoluril hexamer (CB[6]) was dubbed "cucurbituril" by Mock and co-workers because of its resemblance to the most prominent member of the cucurbitaceae family of plants--the pumpkin.
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Cucurbituril homologues and derivatives: new opportunities in supramolecular chemistry.
TL;DR: This Account is a compilation of recent literature covering the syntheses of the homologues and derivatives, and their supramolecular chemistry of cucurbituril, a synthetic receptor.
Journal ArticleDOI
New Cucurbituril Homologues: Syntheses, Isolation, Characterization, and X-ray Crystal Structures of Cucurbit[n]uril (n = 5, 7, and 8)
Jaheon Kim,In-Sun Jung,Soo Young Kim,Eunsung Lee,Jin-Koo Kang,Shigeru Sakamoto,and Kentaro Yamaguchi,Kimoon Kim +7 more
Journal ArticleDOI
Nanotechnology in Drug Delivery and Tissue Engineering: From Discovery to Applications
TL;DR: Two important aspects of nanomedicine, drug delivery and tissue engineering are discussed, highlighting the advances the authors have recently experienced, the challenges they are currently facing, and what they are likely to witness in the near future.
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