Journal ArticleDOI
Effect of atenolol on cadmium-induced testicular toxicity in male rats
TLDR
It is concluded that atenolol may protect testicular androgen synthesis by inhibiting the action of noradrenaline on testicular Leydig cells and adrenocortical hyperactivity in cadmium-treated rats.About:
This article is published in Reproductive Toxicology.The article was published on 2001-11-01. It has received 77 citations till now. The article focuses on the topics: Atenolol & Corticosterone.read more
Citations
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Journal ArticleDOI
Oxidative Stress in Lead and Cadmium Toxicity and Its Amelioration
TL;DR: The present review focuses on mechanism of lead- and cadmium-induced oxidate damages and the ameliorative measures to counteract the oxidative damage and pathotoxicity with the use of supplemented antioxidants for their beneficial effects.
Journal ArticleDOI
Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan.
TL;DR: Overall this study showed that TCS decreased the synthesis of androgens followed by reduced sperm production in treated male rats which could be mediated by a decreased synthesis of LH and FSH thus involving hypothalamo-pituitary-gonadal axis.
Journal ArticleDOI
Testis response to low doses of cadmium in Wistar rats.
TL;DR: The results show that a very small difference of Cd dose causes a sudden increase in testicular damage, apparently overpowering this tissue’s natural defences.
Journal ArticleDOI
Synergistic Effects of Heavy Metals and Pesticides in Living Systems.
TL;DR: The information included in this article may be useful for different environment protection agencies and policy makers to consider the combined effects of heavy metals and pesticides on humans while designing strategies toward environmental protection and safety regulations about human health.
Journal ArticleDOI
Stress-induced increase of testosterone: contributions of social status and sympathetic reactivity.
TL;DR: It is suggested that the reason for the temporary increase of T concentration in the blood in the initial phase of stress, especially when the level of LH is relatively stable, is due to the increased sensitivity of testicles to LH.
References
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Book
Methods of Biochemical Analysis
TL;DR: The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins Immunoassay with Electrochemical Detection and Theory and Newer Technology Assays for Superoxide Dismutase are studied.
Book ChapterDOI
11 beta-Hydroxysteroid dehydrogenase.
TL;DR: Over the 10 years, 11 beta-HSD has progressed from an enzyme merely involved in the peripheral metabolism of cortisol to a crucial pre-receptor signaling pathway in the analysis of corticosteroid hormone action.
Journal ArticleDOI
A rapid, simplified procedure for simultaneous assay of norepinephrine, dopamine, and 5-hydroxytryptamine from discrete brain areas
M.Kent Shellenberger,J.H. Gordon +1 more
TL;DR: Brain, NE, DA, and 5-HT can be assayed simultaneously from discrete samples by this method, which is based upon the alumina method described by Anton and Sayre, utilizing acid extraction of tissues and a single solvent step.
Journal ArticleDOI
Fluorometric Determination of Corticosterone and Cortisol in 0.02–0.05 Milliliters of Plasma or Submilligram Samples of Adrenal Tissue1
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Direct inhibitory effect of glucocorticoids upon testicular luteinizing hormone receptor and steroidogenesis in vivo and in vitro.
TL;DR: The direct inhibitory effect of glucocorticoids on testicular LH receptor content and steroidogenesis is demonstrated, suggesting the adrenal glucocORTicoids may regulate testis functions.