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Open AccessJournal ArticleDOI

Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

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TLDR
In this article, the authors quantify the effect of physical inactivity on these major non-communicable diseases by estimating how much disease could be averted if inactive people were to become active and to estimate gain in life expectancy at the population level.
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This article is published in The Lancet.The article was published on 2012-07-21 and is currently open access. It has received 6119 citations till now. The article focuses on the topics: Life expectancy & Population.

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Journal ArticleDOI

Impact of Physical Activity in Cardiovascular and Musculoskeletal Health: Can Motion Be Medicine?

TL;DR: Assessment of the effect of various levels of physical activity on cardiovascular and musculoskeletal health revealed that physical activity may decrease cardiovascular disease and improve OA symptoms, and therefore, motion can be considered a “medicine”.
Journal ArticleDOI

If my muscle could talk: Myokines as a biomarker of frailty.

TL;DR: The rationale to support the use of myokines as biomarkers of frailty in older adults, a set of cytokines, small proteins and proteoglycan peptides that are synthetized, expressed and released by skeletal myocytes in response to muscular contractions is discussed.
Book ChapterDOI

Exercise and cerebrovascular plasticity.

TL;DR: To understand the beneficial effects of exercise on the cerebral vasculature, the issue of changes in cerebral blood flow and its regulation during acute bouts of exercise is discussed and how regular exercise improves cerebrovascular plasticity will be discussed.
References
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Journal ArticleDOI

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

TL;DR: Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
Journal ArticleDOI

Physical Activity, All-Cause Mortality, and Longevity of College Alumni

TL;DR: With or without consideration of hypertension, cigarette smoking, extremes or gains in body weight, or early parental death, alumni mortality rates were significantly lower among the physically active than among less active men.
Journal ArticleDOI

Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women: A Meta-analysis

TL;DR: In this article, a systematic literature search was conducted for observational cohort studies using MEDLINE (1966 to December 31, 2008) and EMBASE (1980 to December 30, 2008), which reported associations of baseline cardiorespiratory fitness with CHD events, CVD events, or all-cause mortality in healthy participants.
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