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Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy

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TLDR
In this article, the authors quantify the effect of physical inactivity on these major non-communicable diseases by estimating how much disease could be averted if inactive people were to become active and to estimate gain in life expectancy at the population level.
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This article is published in The Lancet.The article was published on 2012-07-21 and is currently open access. It has received 6119 citations till now. The article focuses on the topics: Life expectancy & Population.

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Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study

TL;DR: In a large US sample, physical exercise was significantly and meaningfully associated with self-reported mental health burden in the past month, and differences as a function of exercise were large relative to other demographic variables such as education and income.
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Exercise is the Real Polypill

TL;DR: In this article, a review summarizes the current body of knowledge on the main biological mediators (ingredients) of the preventive/therapeutic effects of regular exercise, and summarizes their roles.
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The Science and Translation of Lactate Shuttle Theory

TL;DR: Clinical studies are utilizing lactate to treat pro-inflammatory conditions and to deliver optimal fuel for working muscles in sports medicine and "Lactate shuttle" concepts describe the roles of lactate in delivery of oxidative and gluconeogenic substrates as well as in cell signaling.
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Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis

TL;DR: Analyzing data from over 650,000 individuals, Dr. Steven Moore and colleagues report that greater amounts of leisure-time physical activity were associated with higher life expectancy across a wide range of activity levels and body mass index groups.
References
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Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

TL;DR: Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
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Physical Activity, All-Cause Mortality, and Longevity of College Alumni

TL;DR: With or without consideration of hypertension, cigarette smoking, extremes or gains in body weight, or early parental death, alumni mortality rates were significantly lower among the physically active than among less active men.
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Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women: A Meta-analysis

TL;DR: In this article, a systematic literature search was conducted for observational cohort studies using MEDLINE (1966 to December 31, 2008) and EMBASE (1980 to December 30, 2008), which reported associations of baseline cardiorespiratory fitness with CHD events, CVD events, or all-cause mortality in healthy participants.
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