Effects of 4- and 6-h Time-Restricted Feeding on Weight and Cardiometabolic Health: A Randomized Controlled Trial in Adults with Obesity.
Sofia Cienfuegos,Kelsey Gabel,Faiza Kalam,Mark Ezpeleta,Eric Wiseman,Vasiliki Pavlou,Shuhao Lin,Manoela Lima Oliveira,Krista A. Varady +8 more
TLDR
It is suggested that 4- and 6-h TRF induce mild reductions in body weight over 8 weeks and show promise as interventions for weight loss and may also improve some aspects of cardiometabolic health.About:
This article is published in Cell Metabolism.The article was published on 2020-09-01 and is currently open access. It has received 221 citations till now. The article focuses on the topics: Weight loss.read more
Citations
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Calorie Restriction with or without Time-Restricted Eating in Weight Loss
TL;DR: In this article , the authors randomly assigned 139 patients with obesity to time-restricted eating (eating only between 8:00 a.m. and 4:00 p.m.) with calorie restriction or daily calorie restriction alone.
Journal ArticleDOI
Calorie Restriction with or without Time-Restricted Eating in Weight Loss.
Deying Liu,Yan Huang,Chensihan Huang,Shunyu Yang,Xue-Dong Wei,Peizhen Zhang,Dan Guo,Jiayang Lin,Bin-Bin Xu,Changwei Li,Hua He,Jiang He,Shiqun Liu,Linna Shi,Yaoming Xue,Huijie Zhang +15 more
TL;DR: Among patients with obesity, a regimen of time-restricted eating was not more beneficial with regard to reduction in body weight, body fat, or metabolic risk factors than daily calorie restriction.
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Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care.
TL;DR: In this paper, a review explores the latest work and emerging ideas related to genetic and environmental factors influencing metabolism and highlights translational research and clinical applications, including the impact of the COVID-19 pandemic.
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Current Concepts, Opportunities, and Challenges of Gut Microbiome-Based Personalized Medicine in Nonalcoholic Fatty Liver Disease.
TL;DR: It is highlighted how the current knowledge of the gut-liver axis in NAFLD may be leveraged to develop gut microbiome-based personalized approaches for disease management, including its use as a non-invasive biomarker for diagnosis and staging, as a target for therapeutic modulation, and as a marker of drug response.
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Intermittent and periodic fasting, longevity and disease
TL;DR: The different fasting methods are described and their effect on longevity in organisms ranging from yeast to humans, linking them to the major nutrient-sensing signaling pathways and focusing on the benefits of the fasting and the refeeding periods.
References
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Reactive oxygen species have a causal role in multiple forms of insulin resistance.
TL;DR: A genomic analysis of two cellular models of insulin resistance, one induced by treatment with the cytokine tumour-necrosis factor-α and the other with the glucocorticoid dexamethasone, suggests that reactive oxygen species levels are increased in both models, and increased ROS levels are an important trigger for insulin resistance in numerous settings.
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Adverse metabolic and cardiovascular consequences of circadian misalignment
TL;DR: The findings demonstrate the adverse cardiometabolic implications of circadian misalignment, as occurs acutely with jet lag and chronically with shift work, on metabolic, autonomic, and endocrine predictors of obesity, diabetes, and cardiovascular risk.
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Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial.
TL;DR: Overall dietary adherence rates were low, although increased adherence was associated with greater weight loss and cardiac risk factor reductions for each diet group, and each popular diet modestly reduced body weight and several cardiac risk factors at 1 year.
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Oxidative stress, insulin signaling, and diabetes.
Justin L. Rains,Sushil K. Jain +1 more
TL;DR: Overall, this review outlines various mechanisms that lead to the development of oxidative stress and intervention and therapy that alter or disrupt these mechanisms may serve to reduce the risk of insulin resistance and theDevelopment of diabetes.
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Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes.
Elizabeth F. Sutton,Robbie A. Beyl,Kate S. Early,William T. Cefalu,William T. Cefalu,Eric Ravussin,Courtney M. Peterson,Courtney M. Peterson +7 more
TL;DR: It is demonstrated for the first time in humans that eTRF improves some aspects of cardiometabolic health and that IF's effects are not solely due to weight loss.