Embryonic cleavage cycles: how is a mouse like a fly?
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TLDR
It is proposed that comparison to the rapid peri-gastrulation cycles is more appropriate and suggested that these cycles are related by evolutionary descent to the early cleavage stages of embryos such as those of frog and fly.About:
This article is published in Current Biology.The article was published on 2004-01-06 and is currently open access. It has received 204 citations till now. The article focuses on the topics: Embryonic cleavage.read more
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Genetic and Epigenetic Regulators of Pluripotency
TL;DR: Genetic and epigenetic mechanisms regulate the transition from the totipotent zygote to pluripotent primitive ectoderm cells in the inner cell mass of mouse blastocysts, and increasing knowledge of key underlying mechanisms heightens prospects for creating pluripresent cells directly from adult somatic cells.
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Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response
TL;DR: The results demonstrate the existence of a p53-dependent checkpoint mechanism that senses changes in the fidelity of the translational machinery to prevent aberrant cell division or eliminate defective T cells in vivo.
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Expression of engrailed proteins in arthropods, annelids and chordates
TL;DR: A monoclonal antibody is described that recognizes a conserved epitope in the homeodomain of engrailed proteins of a number of different arthropods, annelids, and chordates; this antibody is used to isolate the grasshopperEngrailed gene, a homeobox gene that has an important role in Drosophila segmentation.
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Stochastic patterning in the mouse pre-implantation embryo.
TL;DR: In this paper, the distribution of the transcription factors Oct4 (Pou5f1), Cdx2 and Nanog at precisely defined stages in pre-implantation development was identified, leading to the divergence of TE, EPI and epiblast lineages.
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The Maternal-Zygotic Transition: Death and Birth of RNAs
TL;DR: Maternal gene products drive early development when the newly formed embryo is transcriptionally inactive, and during the maternal-zygotic transition, embryonic transcription is initiated and many maternal RNAs are degraded.
References
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Book
The Genetics and biology of Drosophila
TL;DR: This is the first attempt since 1925 to publish a comprehensive account of the biology and genetics of Drosophila and it aims to collate the dauntingly large literature on the subject and to make more accessible the private language ot the Dosophilist.
Book
Biology of Spiders
TL;DR: An updated translation of the definitive text on spider biology by the author of the second German-language edition from Thieme Verlag, with greater emphasis on ecology and systematics.
Journal ArticleDOI
Cell Cycle Checkpoints: Preventing an Identity Crisis
TL;DR: Signal transduction pathways that transmit checkpoint signals in response to DNA damage, replication blocks, and spindle damage are revealed, underscoring the conservation of cell cycle regulatory machinery.
Book
Drosophila: A Laboratory Handbook
TL;DR: This manual covers three approaches to the field: analysis of neural development, recording and imaging activities in the nervous system, and analysis of behavior.
Related Papers (5)
A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage
DNA-replication checkpoint control at the Drosophila midblastula transition
Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis
V.E. Foe,B.M. Alberts +1 more