Journal ArticleDOI
Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance.
Yiwen Deng,Keran Zhai,Zhen Xie,D. Yang,Xudong Zhu,Junzhong Liu,Xin Wang,Peng Qin,Yuanzhu Yang,Guomin Zhang,Qun Li,Jianfu Zhang,Shuangqing Wu,Joëlle Milazzo,Bizeng Mao,Ertao Wang,Huaan Xie,Didier Tharreau,Zuhua He,Zuhua He +19 more
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TLDR
It is reported that the rice Pigm locus contains a cluster of genes encoding nucleotide-binding leucine-rich repeat (NLR) receptors that confer durable resistance to the fungus Magnaporthe oryzae without yield penalty.Abstract:
Crop breeding aims to balance disease resistance with yield; however, single resistance (R) genes can lead to resistance breakdown, and R gene pyramiding may affect growth fitness. Here we report that the rice Pigm locus contains a cluster of genes encoding nucleotide-binding leucine-rich repeat (NLR) receptors that confer durable resistance to the fungus Magnaporthe oryzae without yield penalty. Among these NLR receptors, PigmR confers broad-spectrum resistance, whereas PigmS competitively attenuates PigmR homodimerization to suppress resistance. PigmS expression, and thus PigmR-mediated resistance, are subjected to tight epigenetic regulation. PigmS increases seed production to counteract the yield cost induced by PigmR. Therefore, our study reveals a mechanism balancing high disease resistance and yield through epigenetic regulation of paired antagonistic NLR receptors, providing a tool to develop elite crop varieties.read more
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Dynamics and function of DNA methylation in plants.
TL;DR: DNA methylation in plants mediates gene expression, transposon silencing, chromosome interactions and genome stability, and the regulation of DNA methylation is important for plant development and for plant responses to biotic and abiotic stresses.
Journal ArticleDOI
Pan-Genome of Wild and Cultivated Soybeans.
Yucheng Liu,Huilong Du,Pengcheng Li,Yanting Shen,Hua Peng,Shu-Lin Liu,Guoan Zhou,Haikuan Zhang,Zhi Liu,Miao Shi,Xuehui Huang,Yan Li,Min Zhang,Zheng Wang,Baoge Zhu,Bin Han,Chengzhi Liang,Zhixi Tian +17 more
TL;DR: The structural variations from the 2,898 accessions that were genotyped based on the graph-based genome and the RNA sequencing data from the representative 26 accessions helped to link genetic variations to candidate genes that are responsible for important traits.
Journal ArticleDOI
Mechanisms to Mitigate the Trade-Off between Growth and Defense.
TL;DR: This review focuses on how costs are generated and whether and how they can be mitigated, and examines the resistance (R) genes as a case study of how the toll of defense can be generated and ameliorated.
Journal ArticleDOI
Metabolites as regulators of insulin sensitivity and metabolism
TL;DR: A comprehensive understanding of the metabolic adaptations involved in insulin resistance may enable the identification of novel targets for improving insulin sensitivity and preventing, and treating, T2DM.
Journal ArticleDOI
NLR network mediates immunity to diverse plant pathogens.
Chih-Hang Wu,Ahmed Abd-El-Haliem,Tolga O. Bozkurt,Tolga O. Bozkurt,Khaoula Belhaj,Ryohei Terauchi,Jack H. Vossen,Sophien Kamoun +7 more
TL;DR: A complex NLR immune network is discovered in which helper NLRs in the NRC (NLR required for cell death) family are functionally redundant but display distinct specificities toward different sensor NLRs that confer immunity to oomycetes, bacteria, viruses, nematodes, and insects.
References
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Journal ArticleDOI
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
TL;DR: Bowtie extends previous Burrows-Wheeler techniques with a novel quality-aware backtracking algorithm that permits mismatches and can be used simultaneously to achieve even greater alignment speeds.
Journal ArticleDOI
The Barley Mlo Gene: A Novel Control Element of Plant Pathogen Resistance
Rainer Büschges,Karin Hollricher,Ralph Panstruga,Guus Simons,Marietta Wolter,A. Frijters,Raymond van Daelen,Theo van der Lee,Paul Johan Diergaarde,John Groenendijk,Sonja Töpsch,Pieter Vos,Francesco Salamini,Paul Schulze-Lefert +13 more
TL;DR: Analysis of mutagen-induced recessive alleles of the barley Mlo locus revealed mutations leading in each case to alterations of the deduced Mlo wild-type amino acid sequence, compatible with a dual negative control function of the Mlo protein in leaf cell death and in the onset of pathogen defense.
Journal ArticleDOI
Epigenetic Reprogramming and Small RNA Silencing of Transposable Elements in Pollen
R. K. Slotkin,Matthew W. Vaughn,Filipe Borges,Milos Tanurdzic,Jörg Becker,José A. Feijó,José A. Feijó,Robert A. Martienssen +7 more
TL;DR: A conserved role for reprogramming in germline companion cells, such as nurse cells in insects and vegetative nuclei in plants, is proposed to reveal intact TEs in the genome and regulate their activity in gametes.
Journal ArticleDOI
Pivoting the Plant Immune System from Dissection to Deployment
TL;DR: Research over the last 25 years has led to an increasingly clear conceptual understanding of the molecular components of the plant immune system, which means the means to begin development of durable (long-lasting) disease resistance beyond the limits imposed by conventional breeding and in a manner that will replace costly and unsustainable chemical controls.
Journal ArticleDOI
Firefly Luciferase Complementation Imaging Assay for Protein-Protein Interactions in Plants
TL;DR: This assay is simple, reliable, and quantitative in detection of protein-protein interactions in plants, and Mutants that are known to compromise protein- protein interactions showed little or much reduced luciferase activity.
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