scispace - formally typeset
Open AccessJournal ArticleDOI

Gelatin carriers for drug and cell delivery in tissue engineering

Marco Santoro, +2 more
- 28 Sep 2014 - 
- Vol. 190, pp 210-218
TLDR
G gelatin modifications for immune system evasion, drug stabilization, and targeted delivery, as well as gelatin composite systems based on ceramics, naturally-occurring polymers, and synthetic polymers are discussed.
About: 
This article is published in Journal of Controlled Release.The article was published on 2014-09-28 and is currently open access. It has received 278 citations till now. The article focuses on the topics: Gelatin & Drug delivery.

read more

Citations
More filters
Journal ArticleDOI

Injectable hydrogels for cartilage and bone tissue engineering.

Mei Liu, +11 more
- 30 May 2017 - 
TL;DR: The selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering are described and the biology of Cartilage and the bony ECM is summarized.
Journal ArticleDOI

Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair.

Barbara J. Klotz, +5 more
- 01 May 2016 - 
TL;DR: G gelatin-methacryloyl (gelMA) hydrogels have recently gained increased attention and could be used to accelerate the development of clinically relevant applications.
Journal ArticleDOI

Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

Sepehr Talebian, +11 more
- 01 Aug 2019 - 
TL;DR: The recent progress in the development of multifunctional and self‐healable hydrogels for various tissue engineering applications is discussed in detail and their potential applications within the rapidly expanding areas of bioelectronics, cyborganics, and soft robotics are highlighted.
Journal ArticleDOI

Biopolymer-based functional composites for medical applications

Sung-Bin Park, +6 more
- 01 May 2017 - 
TL;DR: This article provides comprehensive knowledge and highlights recent research on functional biopolymer composites used in various medical applications, such as tissue engineering comprising skin, bone, cartilage, vascular graft, and other organs, implantable medical devices including stent and barrier membrane, and some delivery systems of bioactive agents.
Journal ArticleDOI

Drug delivery from gelatin-based systems

Maytal Foox, +1 more
- 12 Aug 2015 - 
TL;DR: The modification of gelatin and its combinations with other biomaterials have demonstrated the flexibility of these systems and can be employed for meeting the challenges of finding ideal carrier systems that enable specific, targeted and controlled release in response to demands in the body.
References
More filters
Journal ArticleDOI

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

Matthias P. Lutolf, +2 more
- 01 Jan 2005 - 
TL;DR: Although modern synthetic biomaterials represent oversimplified mimics of natural ECMs lacking the essential natural temporal and spatial complexity, a growing symbiosis of materials engineering and cell biology may ultimately result in synthetic materials that contain the necessary signals to recapitulate developmental processes in tissue- and organ-specific differentiation and morphogenesis.
Journal ArticleDOI

Foreign body reaction to biomaterials.

James M. Anderson, +2 more
- 01 Apr 2008 - 
TL;DR: A major focus of this review is on factors that modulate the interaction of macrophages and foreign body giant cells on synthetic surfaces where the chemical, physical, and morphological characteristics of the synthetic surface are considered to play a role in modulating cellular events.
Journal ArticleDOI

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

Katrin Knop, +4 more
- 23 Aug 2010 - 
TL;DR: PEG is the most used polymer and also the gold standard for stealth polymers in the emerging field of polymer-based drug delivery and alternative polymers will be evaluated.
Journal ArticleDOI

Design and development of polymers for gene delivery

Daniel W. Pack, +3 more
- 01 Jul 2005 - 
TL;DR: With the growing understanding of polymer gene-delivery mechanisms and continued efforts of creative polymer chemists, it is likely that polymer-based gene-Delivery systems will become an important tool for human gene therapy.
Journal ArticleDOI

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

Fabienne Danhier, +2 more
- 01 Dec 2010 - 
TL;DR: Delivery of conventional chemotherapeutic anti-cancer drugs is mainly discussed and exploitation and the understanding of these characteristics to design new drug delivery systems targeting the tumor are focused on.
Related Papers (5)

Gelatin as a delivery vehicle for the controlled release of bioactive molecules.

Simon Young, +3 more
- 05 Dec 2005 - 

Functional and bioactive properties of collagen and gelatin from alternative sources: A review

M.C. Gómez-Guillén, +3 more
- 01 Dec 2011 - 

Cell-laden microengineered gelatin methacrylate hydrogels.

Jason W. Nichol, +11 more
- 01 Jul 2010 - 

Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels

Kan Yue, +12 more
- 01 Dec 2015 - 

Alginate: properties and biomedical applications

Kuen Yong Lee, +1 more
- 01 Jan 2012 - 
Frequently Asked Questions (1)
Q1. What have the authors contributed in "Gelatin carriers for drug and cell delivery in tissue engineering" ?

In this review, the authors highlight some of the latest work being performed in these areas and comment on trends in the field. Specifically, the authors discuss gelatin modifications for immune system evasion, drug stabilization, and targeted delivery, as well as gelatin composite systems based on ceramics, naturally-occurring polymers, and synthetic polymers.