Genetics of ecological divergence during speciation
Matthew E. Arnegard,Matthew D. McGee,Blake Matthews,Kerry B. Marchinko,Gina L. Conte,Sahriar Kabir,Nicole L. Bedford,Sara Bergek,Yingguang Frank Chan,Felicity C. Jones,David M. Kingsley,Catherine L. Peichel,Dolph Schluter +12 more
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It is shown that multiple, unlinked loci act largely additively to determine position along the major niche axis separating these recently diverged species and it is found that functional mismatch between phenotypic traits reduces the growth of some stickleback hybrids beyond that expected from an intermediate phenotype.Abstract:
Ecological differences often evolve early in speciation as divergent natural selection drives adaptation to distinct ecological niches, leading ultimately to reproductive isolation. Although this process is a major generator of biodiversity, its genetic basis is still poorly understood. Here we investigate the genetic architecture of niche differentiation in a sympatric species pair of threespine stickleback fish by mapping the environment-dependent effects of phenotypic traits on hybrid feeding and performance under semi-natural conditions. We show that multiple, unlinked loci act largely additively to determine position along the major niche axis separating these recently diverged species. We also find that functional mismatch between phenotypic traits reduces the growth of some stickleback hybrids beyond that expected from an intermediate phenotype, suggesting a role for epistasis between the underlying genes. This functional mismatch might lead to hybrid incompatibilities that are analogous to those underlying intrinsic reproductive isolation but depend on the ecological context.read more
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Journal ArticleDOI
Subset Selection in Regression
TL;DR: Chapman and Miller as mentioned in this paper, Subset Selection in Regression (Monographs on Statistics and Applied Probability, no. 40, 1990) and Section 5.8.
Journal ArticleDOI
Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow.
Mark Ravinet,Mark Ravinet,Rui Faria,Rui Faria,Rui Faria,Roger K. Butlin,Roger K. Butlin,Juan Galindo,Nicolas Bierne,Marina Rafajlović,Mohamed A. F. Noor,Bernhard Mehlig,Anja M. Westram +12 more
TL;DR: It is argued that the availability of promising technical and analytical methods will shed further light on the important roles that gene flow and divergent selection have in shaping the genomic landscape of speciation and proposes a road map for future speciation research.
Journal ArticleDOI
Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake.
Milan Malinsky,Milan Malinsky,Richard Challis,Alexandra M. Tyers,Stephan Schiffels,Yohey Terai,Benjamin P. Ngatunga,Eric A. Miska,Eric A. Miska,Richard Durbin,Martin J. Genner,George F. Turner +11 more
TL;DR: The discovery and detailed characterization of early-stage adaptive divergence of two cichlid fish ecomorphs in a small crater lake in Tanzania are reported and mechanisms and genomic regions that may play a role in the closely related mega-radiation of Lake Malawi are suggested.
Journal ArticleDOI
Natural selection interacts with recombination to shape the evolution of hybrid genomes
Molly Schumer,Chenling Xu,Daniel L. Powell,Arun Durvasula,Laurits Skov,Chris Holland,John C. Blazier,Sriram Sankararaman,Peter Andolfatto,Gil G. Rosenthal,Molly Przeworski +10 more
TL;DR: Three replicate hybrid populations that formed naturally between two swordtail fish species are studied, estimating their fine-scale genetic map and inferring ancestry along the genomes of 690 individuals and indicate that selection on swordtail hybrids stems predominantly from deleterious combinations of epistatically interacting alleles.
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