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Journal ArticleDOI

GSH‐Depleted PtCu3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy

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TLDR
PtCu3 nanocages are first reported as acting as a sonosensitizer with highly efficient ROS generation under ultrasound irradiation, and can act as horseradish peroxidase‐like nanozymes, catalyzing the decomposition of H2O2 into •OH under acidic conditions for CDT.
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This article is published in Advanced Functional Materials.The article was published on 2020-01-01. It has received 295 citations till now. The article focuses on the topics: Sonodynamic therapy & Nanocages.

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Multifunctional sonosensitizers in sonodynamic cancer therapy

TL;DR: This review article highlights the recent advances in SDT in terms of sonosensitizers and their formulations and anticancer therapeutic efficacy and the potential ofSDT in combination with other modalities to address unmet needs in precision medicine.
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Recent progress of chemodynamic therapy-induced combination cancer therapy

TL;DR: This review begins by defining CDT, then it identifies the problems faced in CDT and proposes various strategies to enhance CDT performance, primarily focusing on CDT-based combined cancer treatment.
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Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy

TL;DR: This work highlights a new type of titanium-based nanostructure with great performance for tumor SDT, PEG-TiO1+x NRs, which can be used as a sono-sensitizer and CDT agent for highly effective tumor ablation under US treatment.
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GSH-Depleted Nanozymes with Hyperthermia-Enhanced Dual Enzyme-Mimic Activities for Tumor Nanocatalytic Therapy

TL;DR: This study provides a proof of concept of hyperthermia‐augmented multi‐enzymatic activities of nanozymes for tumor ablation by taking advantage of the desirable light absorbance in the second near‐infrared (NIR‐II) window of the PEG/Ce‐Bi@DMSN nanoZymes.
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Recent Advances in Nanomaterial-Assisted Combinational Sonodynamic Cancer Therapy.

TL;DR: The design principles in achieving synergistic therapeutic effects based on nanomaterial engineering methods are highlighted and the ultimate goals are to stimulate the design of better‐quality combined sonodynamic treatment schemes and provide innovative ideas for the perspectives of SDT in promoting its future transformation to clinical application.
References
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Cancer statistics, 2016

TL;DR: Overall cancer incidence trends are stable in women, but declining by 3.1% per year in men, much of which is because of recent rapid declines in prostate cancer diagnoses, and brain cancer has surpassed leukemia as the leading cause of cancer death among children and adolescents.
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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

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TL;DR: Nanotechnology is a multidisciplinary field, which covers a vast and diverse array of devices derived from engineering, biology, physics and chemistry that can provide essential breakthroughs in the fight against cancer.
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Nanoparticles in photodynamic therapy.

TL;DR: This paper presents a meta-modelling study of the response of the immune system to chemotherapy and its applications in the context of central nervous system disorders.
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