Highly Stretchable, Adhesive, Biocompatible, and Antibacterial Hydrogel Dressings for Wound Healing
Yang Zifeng,Rongkang Huang,Bingna Zheng,Guo Wentai,Chuangkun Li,Wenyi He,Yingqi Wei,Yang Du,Huaiming Wang,Dingcai Wu,Hui Wang +10 more
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TLDR
In this paper, cationic polyelectrolyte brushes grafted from bacterial cellulose (BC) nanofibers are introduced into polydopamine/polyacrylamide hydrogels.Abstract:
Treatment of wounds in special areas is challenging due to inevitable movements and difficult fixation. Common cotton gauze suffers from incomplete joint surface coverage, confinement of joint movement, lack of antibacterial function, and frequent replacements. Hydrogels have been considered as good candidates for wound dressing because of their good flexibility and biocompatibility. Nevertheless, the adhesive, mechanical, and antibacterial properties of conventional hydrogels are not satisfactory. Herein, cationic polyelectrolyte brushes grafted from bacterial cellulose (BC) nanofibers are introduced into polydopamine/polyacrylamide hydrogels. The 1D polymer brushes have rigid BC backbones to enhance mechanical property of hydrogels, realizing high tensile strength (21-51 kPa), large tensile strain (899-1047%), and ideal compressive property. Positively charged quaternary ammonium groups of tethered polymer brushes provide long-lasting antibacterial property to hydrogels and promote crawling and proliferation of negatively charged epidermis cells. Moreover, the hydrogels are rich in catechol groups and capable of adhering to various surfaces, meeting adhesive demand of large movement for special areas. With the above merits, the hydrogels demonstrate less inflammatory response and faster healing speed for in vivo wound healing on rats. Therefore, the multifunctional hydrogels show stable covering, little displacement, long-lasting antibacteria, and fast wound healing, demonstrating promise in wound dressing.read more
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Carboxymethyl cellulose-based injectable hydrogel loaded with a composite of melatonin and γ-cyclodextrin with antioxidant property for diabetic wound repair
Yamei Wang,Dongdong Xiao,Yang Tang,Yezhong Xia,Yi Zhong,Linping Zhang,Xiaofeng Sui,Bijia Wang,Xueling Feng,Hong Xu,Zhiping Mao +10 more
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Charge‐Transfer Polymeric Hydrogels with Self‐Healing, Injectable, Thermosensitive, Adhesive, and Antibacterial Properties for Diabetic Wound Healing
Ru Zhang,Cuiwen Liu,Cheng Kun Wei,Jingtao Huang,Xiaohui Zou,Yanxian Feng,Song Ang,Suqin Guo,Jinqing Qu,Ning Qing,Chengcheng Tang,Xiaoqing Zhou,Min Chen,Liuyan Tang +13 more
TL;DR: In this paper , a series of hydrogels with charge transfer (CT) complexes are designed and synthesized for diabetic wound healing, which have good biocompatibility and long-term stability in both ambient and aqueous environments.
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Microgel Assembly Powder Improves Acute Hemostasis, Antibacterial, and Wound Healing via In Situ Co‐Assembly of Erythrocyte and Microgel
TL;DR: In this article , a multi-functional microgel assembly powder (MAP) composed of oxidized dextran/methacrylate gelatin (ODex/GelMA) microgel powder and long-chain alkyl quaternized chitosan (LQCS) crosslinker powder is reported for acute hemostasis, antibacterial, and wound healing.
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Mesoporous TiO2 Coatings Regulate ZnO Nanoparticle Loading and Zn2+ Release on Titanium Dental Implants for Sustained Osteogenic and Antibacterial Activity.
TL;DR: In this article , a potential dental implant modification was creatively developed as ZnO nanoparticle-loaded mesoporous TiO2 coatings (nZnO/MTC-Ti) via the evaporation-induced self-assembly method (EISA) and one-step spin coating.
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Fully rubbery Schottky diode and integrated devices
TL;DR: In this paper , a fully rubbery Schottky diode constructed all based on stretchable electronic materials, including a liquid metal cathode, a rubbery semiconductor, and a stretchable anode, was presented.
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