Hormone-sensitive cholesterol ester hydrolase of bovine adrenal cortex: identification of the enzyme protein.
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TLDR
Evidence strongly suggests that the activity of cholesterol ester hydrolase is regulated by covalent phosphorylation, but proof of this requires that the enzyme protein be identified and phosphate shown to be incorporated into the protein.About:
This article is published in FEBS Letters.The article was published on 1981-09-14 and is currently open access. It has received 35 citations till now. The article focuses on the topics: Cholesterol 7 alpha-hydroxylase & Cholesterol side-chain cleavage enzyme.read more
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Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis.
TL;DR: A model is discussed whereby perilipin serves as a dynamic scaffold to coordinate the access of enzymes to the lipid droplet in a manner that is responsive to the metabolic status of the adipocyte.
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Hormone-sensitive lipase - new roles for an old enzyme
TL;DR: It is now clear that HSL (hormone-sensitive lipase) is expressed in multiple tissues and plays a number of roles in lipid metabolism, including that of a neutral cholesteryl ester hydrolase.
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Hormone-sensitive lipase--a multipurpose enzyme in lipid metabolism.
TL;DR: Revue generale traitant de la lipase hormone sensible, presente dans les tissus adipeux de bovin et de rat, analyse des modifications biochimiques, de la regulation, de the distribution tissulaire de l'enzyme.
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Perilipin A and the control of triacylglycerol metabolism
TL;DR: It is hypothesized that perilipin A binds accessory proteins to provide assistance in carrying out these functions for maximal lipolysis and hormone-sensitive lipase access to lipid substrates.
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Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes.
TL;DR: It is shown for the first time the relative contributions of ATGL, HSL, and Peri A on determination of LD size in the absence of PKA stimulation and in the experimental model system that in the basal state, LD size, triglyceride storage, and fatty acid release are mainly influenced by the expression of AT GL.
References
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Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Maturation of the head of bacteriophage T4. I. DNA packaging events.
Ulrich K. Laemmli,M Favre +1 more
TL;DR: Pulse-chase experiments in wild-type and mutant phage-infected cells provide evidence that the following particles called prohead I, II and III are successive precursors to the mature heads as discussed by the authors.
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Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate
TL;DR: Sodium salicylate has been found to serve as a satisfactory fluor for enhanced detection of radioactivity in polyacrylamide gels and gives linearity and sensitivity comparable to diphenyl oxazole.
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Purification and Control of Bovine Adrenal Cortical Cholesterol Ester Hydrolase and Evidence for the Activation of the Enzyme by a Phosphorylation
TL;DR: It is suggested that bovine adrenal cortex cholesterol ester hydrolase is activated by a phosphorylation catalysed by a cyclic-AMP-dependent protein kinase, dependent on magnesium or calcium ions.
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