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Journal ArticleDOI

In situ gelling hydrogels for pharmaceutical and biomedical applications.

Sophie R. Van Tomme, +2 more
- 01 May 2008 - 
- Vol. 355, Iss: 1, pp 1-18
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TLDR
An overview of in situ gelling systems and their potential in biomedical applications, both photopolymerizable as well as self-assembling hydrogels, based on either chemical crosslinks or physical interactions will be addressed.
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This article is published in International Journal of Pharmaceutics.The article was published on 2008-05-01. It has received 571 citations till now. The article focuses on the topics: Self-healing hydrogels.

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Citations
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy

TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Controlled drug delivery vehicles for cancer treatment and their performance.

TL;DR: The different types of materials used as delivery vehicles for chemotherapeutic agents and their structural characteristics that improve the therapeutic efficacy of their drugs are discussed and recent scientific advances in the area of chemotherapy are described.
Journal ArticleDOI

Hydrogels in a historical perspective: from simple networks to smart materials.

TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
Journal ArticleDOI

Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering

TL;DR: Recent exciting developments in click hydrogels, microgels and nanogels, as well as their biomedical applications such as controlled protein and drug release, tissue engineering, and regenerative medicine are presented and discussed.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
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Biological interactions between polysaccharides and divalent cations: The egg‐box model

TL;DR: It is shown that spedfic binding of divalent cations to a polysaechafide polyelectro]ym, leading firm cohesion between the chains, can cause characteristic effects in the c~rcutar diehroism spectrum which are understandabb in terms of modem theo~, [ l ].
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Hydrophilic Gels for Biological Use

TL;DR: In this article, the structural similarity with the tissue has not been emphasized although physiologically unfavourable effects were observed in most cases of application of normal type plastics in permanent contact with living tissues.
Journal ArticleDOI

Thermosensitive sol-gel reversible hydrogels.

TL;DR: It is timely to summarize the polymeric systems that undergo sol-gel transitions, particularly due to temperature, with emphasis on the underlying transition mechanisms and potential delivery aspects.
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