Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
NCAM Mimetic Peptides: Potential Therapeutic Target for Neurological Disorders.
TL;DR: This review focuses on recent progress in the development of NCAM mimetic peptides, in particular, on establishing C3, plannexin, and FGL as therapeutic candidates for neurological disorders.
Journal ArticleDOI
Bioactive peptides and proteases: characteristics, applications and the simultaneous production in solid-state fermentation
Paola Gouvêa Manfredini,Vítor Augusto Farina Cavanhi,Jorge Alberto Vieira Costa,Luciane Maria Colla +3 more
TL;DR: This work aimed to review the literature on the production of proteases and bioactive peptides through solid-state fermentation, including the simultaneous production of these compounds, since the fermented medium can benefit from the hydrolysis capacity of the enzymes produced by microorganisms.
Book ChapterDOI
Bioactivity Profiling of Peptides From Food Proteins
TL;DR: The diversity, bioactivities, and physicochemical properties of bioactive peptides found in food proteins are described, highlighting their applications in the interphase of food and health.
Journal ArticleDOI
Characterization of Goat Milk Hydrolyzed by Cell Envelope Proteinases from Lactobacillus plantarum LP69: Proteolytic System Optimization, Bioactivity, and Storage Stability Evaluation.
TL;DR: The contribution of CEPs from L. plantarum LP69 in goat milk is depicted, exploring a new way for the development of a functional milk product and application of a stabilizer greatly promoted milk stability.
Journal ArticleDOI
Application of Rotatable Central Composite Design in the Preparation and Optimization of Poly (Lactic-co-Glycolic Acid) Nanoparticles for Controlled Delivery of HSA
TL;DR: In this article, a rotatable central composite design (RCCD) was applied to evaluate the joint influence of three formulation variables: the duration time of homogenization, agitation speed, and volume ratio of organic solvent phase to external aqueous phase.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more