Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
Functional properties and health benefits of bioactive peptides derived from Spirulina: a review
Claudia Anahite Ovando,Júlio Cesar de Carvalho,Gilberto Vinícius de Melo Pereira,Philippe Jacques,Vanete Thomaz Soccol,Carlos Ricardo Soccol +5 more
TL;DR: The functional properties and health benefits of bioactive peptides from Spirulina are reviewed, potential mechanisms by which bioactive components can be exploited in the development of novel foods with special health claims are presented, and recent developments in proteomics, bioactivity screening methods, and opportunities for designing future peptide-based foods are described.
Journal ArticleDOI
Rethinking food-derived bioactive peptides for antimicrobial and immunomodulatory activities
Dominic Agyei,Michael K. Danquah +1 more
TL;DR: Further insightful research on the pharmacokinetics of immunomodulatory peptides in vivo and clinical studies are needed to firmly establish their therapeutic potency.
Journal ArticleDOI
Isolation, identification and synthesis of four novel antioxidant peptides from rice residue protein hydrolyzed by multiple proteases
TL;DR: Both RRPB3 I and III showed synergistic antioxidant activity compared to each of them used alone and all four synthetic peptides showed excellent stability against simulated gastrointestinal proteases, Therefore, the peptides isolated from RRP may be used as potential antioxidants in the food and drug industries.
Journal ArticleDOI
Production of an antimicrobial peptide derived from slaughterhouse by-product and its potential application on meat as preservative.
TL;DR: The α137-141 fragment of hemoglobin, a small and hydrophilic antimicrobial peptide, contains mainly hemoglobin and inhibited the microbial growths under refrigeration during 14days, close to those of the butylated hydroxytoluene (BHT).
Journal ArticleDOI
New trends for a classical enzyme: Papain, a biotechnological success story in the food industry
TL;DR: Papain is clearly a case of industrial and commercial success over the last 40 years, and further efforts are needed in protein engineering and characterization of new mutants to reach the full potential of this enzyme.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
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