Journal ArticleDOI
Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.
Dominic Agyei,Michael K. Danquah +1 more
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.About:
This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.read more
Citations
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Journal ArticleDOI
Impact of conductivity on the performances of electro-acidification and enzymatic hydrolysis phases of bovine hemoglobin by electrodialysis with bipolar membranes for the production of bioactive peptides
TL;DR: In this paper, two different conductivity levels (0.9 and 4.5 mS/cm) were investigated in bipolar/monopolar (anionic and cationic) configuration and compared to conventional hydrolysis in the same conductivity conditions as well as using a buffer solution.
Book ChapterDOI
Peptides for biopharmaceutical applications
TL;DR: With these drivers, peptides are anticipated to occupy an increased share of use in the treatment of health conditions, as well as in performance on the therapeutics market.
Journal ArticleDOI
Encapsulation of dairy protein hydrolysates: Recent trends and future prospects
Maiara Giroldi,Isabel Marie Grambusch,Daniel Neutzling Lehn,Claucia Fernanda Volken de Souza +3 more
TL;DR: Some characteristics of dairy protein hydrolysates affect their acceptance by consumers, such as bitter taste, high hygroscopicity, low solubility, and physiochemical instability as mentioned in this paper.
Book ChapterDOI
Bioactive peptides: Synthesis, functions and biotechnological applications
Vivek Chauhan,Shamsher S. Kanwar +1 more
TL;DR: The present chapter will highlight about bioactive peptides, their sources, production techniques, major uses and biotechnological applications, which contribute significantly toward human health by affecting the cardiovascular, digestive, immune, nervous and endocrine systems.
Journal ArticleDOI
Development of a pilot-scale process to sequester aflatoxin and release bioactive peptides from highly contaminated peanut meal
Brittany L. White,Aaron J. Oakes,Xiaolei Shi,Kristin M. Price,Marshall C. Lamb,Victor S. Sobolev,Timothy H. Sanders,Jack P. Davis +7 more
TL;DR: In this paper, a pilot-scale extraction of protein and sequestration of aflatoxin from peanut meal was evaluated, where aqueous PM dispersions were mixed with two commercial bentonite clays and Alcalase in a jacketed mixer, hydrolysed for 1-h, heated to inactivate protease, and then separated using a decanter.
References
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Journal ArticleDOI
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.
TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI
Bioactive peptides: Production and functionality
TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI
Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more
TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI
Development and biological activities of marine-derived bioactive peptides: A review
Se-Kwon Kim,Isuru Wijesekara +1 more
TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI
Bioactive peptides and proteins from foods: indication for health effects.
TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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Food-derived peptides with biological activity: from research to food applications.
Rainer Hartmann,Hans Meisel +1 more