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Journal ArticleDOI

Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides.

Dominic Agyei, +1 more
- 01 May 2011 - 
- Vol. 29, Iss: 3, pp 272-277
TLDR
The plausibility of manufacturing pharmaceutical-grade bioactive peptides from food proteins; the challenges and some implementable strategies for overcoming those challenges are discussed.
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This article is published in Biotechnology Advances.The article was published on 2011-05-01. It has received 287 citations till now.

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Citations
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Journal ArticleDOI

The Influence of the Extent of Enzymatic Hydrolysis on Antioxidative Properties and ACE-Inhibitory Activities of Protein Hydrolysates from Goby ( Zosterisessor ophiocephalus ) Muscle

TL;DR: The obtained results revealed that antioxidant and ACE-inhibitory activities of GPHs were influenced by the degree of hydrolysis, and small peptides were essential to obtain high ACE inhibitory activity.
Journal ArticleDOI

Harnessing slaughterhouse by-products: From wastes to high-added value natural food preservative.

TL;DR: This peptide fraction was validated as a natural preservative and substitute for synthetic additives against food spoilage and fits perfectly with the concept of circular economy.
Journal ArticleDOI

Partial characterization and anticancer activities of purified glycoprotein extracted from green seaweed Codium decorticatum

TL;DR: Analysis of anticancer potential of this GLP revealed a remarkable inhibition of cell growth in breast, cervical and lung cancer cells.
Journal ArticleDOI

Bioactive peptides derived from bovine and porcine co-products: A review

TL;DR: In this paper, the potential of protein co-products for use as substrates for bioactive peptide generation with varied bioactivities including antioxidant, antimicrobial, and antihypertensive properties is discussed.
Journal ArticleDOI

Potential ACE-inhibitory activity and nanoLC-MS/MS sequencing of peptides derived from aflatoxin contaminated peanut meal

TL;DR: In this paper, a method for sequestering aflatoxin from contaminated peanut meal (PM) using commercial bentonite clays while protein is simultaneously extracted and hydrolyzed by a commercial protease was developed.
References
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Journal ArticleDOI

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.

TL;DR: The role of cationic host-defense peptides in modulating the innate immune response and boosting infection-resolving immunity while dampening potentially harmful pro-inflammatory (septic) responses gives these peptides the potential to become an entirely new therapeutic approach against bacterial infections.
Journal ArticleDOI

Bioactive peptides: Production and functionality

TL;DR: A variety of naturally formed bioactive peptides have been found in fermented dairy products, such as yoghurt, sour milk and cheese as mentioned in this paper, but the health benefits attributed to peptides in these traditional products have, so far, not been established, however.
Journal ArticleDOI

Food-derived peptides with biological activity: from research to food applications.

TL;DR: Several products are already on the market or under development by food companies that exploit the potential of food-derived bioactive peptides and which ascribe scientifically evidenced health claims to consumption of these functional foods.
Journal ArticleDOI

Development and biological activities of marine-derived bioactive peptides: A review

TL;DR: An overview of the bioactive peptides derived from marine organisms and their biological activities with potential applications in different areas is presented.
Journal ArticleDOI

Bioactive peptides and proteins from foods: indication for health effects.

TL;DR: There is evidence for the antihypertensive effects of milk products fermented with Lactobacillus helveticus containing the tripeptides IPP and VPP, which inhibit angiotensin converting enzyme, and for osteoprotective effects by milk basic protein.
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